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Condition: Thrombocytopenia
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Total 366 results found since Jan 2013.
Safety of COVID-19 Vaccines among Patients with Type 2 Diabetes Mellitus: Real-World Data Analysis
CONCLUSION: Careful monitoring of severe AEs in patients with T2DM may be necessary, especially for those related to thrombotic events and neurological dysfunctions after COVID-19 vaccination.PMID:36872064 | DOI:10.4093/dmj.2022.0129
Source: Diabetes and Metabolism Journal - March 5, 2023 Category: Endocrinology Authors: Hye Jun Kim Sang Jun Lee Soonok Sa Jung Ho Bae Gyuseon Song Chae Won Lee Ju Hee Kim Sung Ryul Shim Myunghee Hong Hyun Wook Han Source Type: research
Investigation of Neurological Complications after COVID-19 Vaccination: Report of the Clinical Scenarios and Review of the Literature
Vaccines (Basel). 2023 Feb 13;11(2):425. doi: 10.3390/vaccines11020425.ABSTRACTCoronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in 2019 and became a pandemic in 2020. Since then, vaccines have been approved to prevent severe illness. However, vaccines are associated with the risk of neurological complications ranging from mild to severe. Severe complications such as vaccine-induced immune thrombotic thrombocytopenia (VITT) associated with acute ischaemic stroke have been reported as rare complications post-COVID-19 vaccination. During the pandemic era, V...
Source: Herpes - February 28, 2023 Category: Infectious Diseases Authors: Wei-Ping Chen Ming-Hua Chen Shih-Ta Shang Yung-Hsi Kao Kuo-An Wu Wen-Fang Chiang Jenq-Shyong Chan Hann-Yeh Shyu Po-Jen Hsiao Source Type: research
Thrombocytopenia Following Perceval Sutureless Aortic Valve Replacement in Asian Patients
CONCLUSIONS: Thrombocytopenia was common after Perceval sutureless AVR, although its impact was not significant. Although Perceval sutureless AVR was found to be a safe and effective option, preoperative assessment of potential bleeding should be performed and the Perceval valve should not be used for patients with a high bleeding risk.PMID:36709983 | DOI:10.1253/circj.CJ-22-0587
Source: Circulation Journal - January 29, 2023 Category: Cardiology Authors: Taisuke Nakayama Yoshitsugu Nakamura Fumiaki Shikata Masaki Ushijima Yuto Yasumoto Daiki Yoshiyama Miho Kuroda Shintaro Sawa Ryo Tsuruta Akira Furutachi Takuya Narita Yujiro Ito Source Type: research
Early high-dose intravenous immunoglobulin for refractory heparin-induced thrombocytopenia with stroke: Two case reports
Heparin-induced thrombocytopenia (HIT) is a drug reaction caused by anti-platelet factor 4 (PF4)/heparin antibodies of the IgG class that activate through Fc γ receptors on platelets and monocytes. They consume platelets and increase thrombin generation.1 HIT occurs 5 to 14 days after the start of heparinization.2 Management of HIT involves discontinuing heparin and switching to an alternative anticoagulant to prevent thrombosis and normalize platelet l evels.3–5 Autoimmune HIT (aHIT), which maintains marked heparin-independent platelet activation even after discontinuing heparin, has recently attracted attention.
Source: Journal of Stroke and Cerebrovascular Diseases - January 24, 2023 Category: Neurology Authors: Naoki Makita, Tomoyuki Ohara, Yukiko Tsuji, Tetsuhiro Ueda, Takuma Nakamura, Toshiki Mizuno, Masahiro Makino Tags: Case Report Source Type: research
A case of ischemic stroke and transient thrombocytopenia in a young female following adenoviral vector-based COVID-19 vaccination: Was the association incidental or causal?
We report a 23-year-old healthy female who developed seizures, altered sensorium, and left hemiparesis, 20 days after receiving the first dose of adenoviral vector-based COVID-19 vaccine "Covishield™." The patient had transient thrombocytopenia. The D-dimer level was 2460 ng/mL. Magnetic resonance imaging (MRI) demonstrated occlusion of M2 segment of the middle cerebral artery and cerebral infarction. Platelet factor-4 antibodies level was normal. Treatment with aspirin and antiepileptic drugs resulted in a remarkable recovery. This is the first Indian case report of ischemic stroke and transient thrombocytopenia followi...
Source: Primary Care - January 9, 2023 Category: Primary Care Authors: Shweta Pandey Ravindra Kumar Garg Pooja Tripathi Hardeep S Malhotra Neeraj Kumar Source Type: research
Challenging Cases in Cerebrovascular Disease
We present four cases of stroke of uncommon cause and remind clinicians to be open minded to the many possible causes of stroke, in particular because early recognition and treatment is often critical. Case 1 discusses a patient with inflammatory cerebral amyloid angiopathy. The presentation, ability to recur, and current treatment considerations are reviewed. Case 2 discusses microangiopathic thrombotic angiopathy. Diagnosis and treatment are considered. An association with interferon therapy and the evolving terminology of this and related conditions are discussed. Case 3 discusses intracranial hemorrhage secondary to ac...
Source: Seminars in Neurology - January 9, 2023 Category: Neurology Authors: Kelly, Michael A. Singh, Jasmine Balabanov, Alexandra Wadina, Adam Dasovic, Braden Tags: Review Article Source Type: research
Large vessel stroke and isolated thrombocytopenia as presenting features of thrombotic thrombocytopenic purpura
Source: Neurological Sciences - December 13, 2022 Category: Neurology Source Type: research
Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study
Fatal complications have occurred after vaccination with ChAdOx1 nCoV-19, a vaccine against Covid-19. Vaccine-induced immune thrombotic thrombocytopenia (VITT) with severe outcome is characterized by venous thrombosis, predominantly in cerebral veins, thrombocytopenia and anti-PF4/polyanion antibodies. Prolonged headaches and cutaneous hemorrhages, frequently observed after the ChAdOx1 nCoV-19 vaccine, have therefore caused anxiety among vaccinees. We investigated whether these symptoms represent a mild form of VITT, with a potential for aggravation, e.g.
Source: Journal of Stroke and Cerebrovascular Diseases - November 17, 2022 Category: Neurology Authors: Nina Haagenrud Schultz, Arne Vasli Lund S øraas, Ingvild Hausberg Sørvoll, Çigdem Akalin Akkök, Annette Vetlesen, Jagjit Singh Bhamra, Maria Therese Ahlen, Pål Andre Holme, Anne-Hege Aamodt, Karolina Skagen, Thor Håkon Skattør, Mona Skjelland, Mark Source Type: research
A post-marketing safety assessment of COVID-19 mRNA vaccination for serious adverse outcomes using administrative claims data linked with vaccination registry in a city of Japan
CONCLUSION: The findings suggested that the COVID-19 mRNA vaccine was generally safe, whilst a signal of pulmonary embolism following the first dose of the COVID-19 mRNA vaccine was observed.PMID:36371366 | DOI:10.1016/j.vaccine.2022.10.088
Source: Vaccine - November 12, 2022 Category: Allergy & Immunology Authors: Yoshinori Takeuchi Masao Iwagami Sachiko Ono Nobuaki Michihata Kohei Uemura Hideo Yasunaga Source Type: research
