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Cardiovascular Outcomes Post Percutaneous Coronary Intervention in Patients with Obstructive Sleep Apnea and Type  2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
ConclusionOSA was associated with a significant increase in all-cause mortality and MACEs post PCI in these patients with T2DM. Therefore, special care and continuous follow-up might be required for patients with T2DM with associated OSA after PCI. However, as a result of the limited number of participants, further larger studies would be required to confirm these hypotheses.
Source: Diabetes Therapy - June 25, 2020 Category: Endocrinology Source Type: research

Obstructive sleep apnea is associated with increased coronary plaque instability: an optical frequency domain imaging study
AbstractObstructive sleep apnea (OSA) is associated with coronary artery disease (CAD) and with an increased risk for myocardial infarction, stroke or death due to cardiovascular disease. Optical frequency-domain imaging (OFDI) is a useful modality for evaluating the characteristics of atherosclerotic plaque. The purpose of the study was to use OFDI to investigate the association of OSA with coronary plaque characteristics in patients undergoing percutaneous coronary intervention (PCI). We retrospectively analyzed OFDI data for coronary artery plaques from 15 patients with OSA and 35 non –OSA patients treated between Oct...
Source: Heart and Vessels - July 10, 2019 Category: Cardiology Source Type: research

Association of obstructive sleep apnea with cardiovascular outcomes after percutaneous coronary intervention: A systematic review and meta-analysis
The relationship between obstructive sleep apnea (OSA) and adverse cardiovascular outcomes in patients undergoing percutaneous coronary intervention (PCI) remains unclear. We performed a systematic review and meta-analysis to assess the impact of OSA on subsequent cardiovascular events after PCI. We searched the PubMed, EMBASE, and Cochrane library from their inceptions to August 5, 2017. We included cohort studies that described the association between OSA (based on apnea-hypopnea index) and cardiovascular outcomes after PCI with stenting. The primary endpoint was major adverse cardiovascular event (MACE), including all-...
Source: Medicine - April 1, 2018 Category: Internal Medicine Tags: Research Article: Meta-Analysis of Observ Studies in Epidemiology Source Type: research

Obstructive sleep apnea increases the risk of cardiac events after percutaneous coronary intervention: a meta-analysis of prospective cohort studies
ConclusionsIn patients after PCI, OSA appears to increase the risk of cardiac death, non-fatal MI, and coronary revascularization.
Source: Sleep and Breathing - April 18, 2017 Category: Respiratory Medicine Source Type: research

Obstructive sleep apnea increases the risk of cardiac events after percutaneous coronary intervention: a meta-analysis of prospective cohort studies.
CONCLUSIONS: In patients after PCI, OSA appears to increase the risk of cardiac death, non-fatal MI, and coronary revascularization. PMID: 28421375 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - April 18, 2017 Category: Sleep Medicine Authors: Qu H, Guo M, Zhang Y, Shi DZ Tags: Sleep Breath Source Type: research

Obstructive Sleep Apnea and Cardiovascular Events After Percutaneous Coronary Intervention.
CONCLUSIONS: -OSA is independently associated with subsequent MACCE in patients undergoing PCI. Evaluation of therapeutic approaches to mitigate OSA-associated risk is warranted. Clinical Trial Registration Information-ClinicalTrials.gov. Identifier: NCT01306526. PMID: 27178625 [PubMed - as supplied by publisher]
Source: Circulation - May 12, 2016 Category: Cardiology Authors: Lee CH, Sethi R, Li R, Ho HH, Hein T, Jim MH, Loo G, Koo CY, Gao XF, Chandra S, Yang XX, Furlan SF, Ge Z, Mundhekar A, Zhang WW, Uchôa CH, Kharwar RB, Chan PF, Chen SL, Chan MY, Richards A, Tan HC, Ong TH, Roldan G, Tai BC, Drager LF, Zhang JJ Tags: Circulation Source Type: research

Prognostic implication of obstructive sleep apnea diagnosed by post-discharge sleep study in patients presenting with acute coronary syndrome
Conclusion: OSA diagnosed in patients treated with percutaneous coronary intervention for ACS by post-discharge sleep studies conducted 2weeks after percutaneous coronary intervention was independently associated with MACCEs at 24-month follow-up.
Source: Sleep Medicine - April 14, 2014 Category: Sleep Medicine Authors: Germaine Loo, Adeline Y. Tan, Chieh-Yang Koo, Bee-Choo Tai, Mark Richards, Chi-Hang Lee Tags: Original Articles Source Type: research

Impact of Obstructive Sleep Apnea on Cardiovascular Outcomes in Patients Treated With Percutaneous Coronary Intervention: Rationale and Design of the Sleep and Stent Study
ABSTRACT Elucidating the effects of obstructive sleep apnea (OSA) on cardiovascular outcomes is crucial in risk assessments and therapeutic recommendations for affected individuals. The Sleep and Stent Study is a multicenter observational study investigating the relationships between OSA and cardiovascular outcomes in patients treated with percutaneous coronary intervention (PCI). Eight centers in 5 countries (Singapore, China and Hong Kong, India, Myanmar, and Brazil) are participating in the study, and the recruitment target is 1600 patients. Adult patients age 18 to 80 years who have undergone successful PCI are eligibl...
Source: Clinical Cardiology - February 22, 2014 Category: Cardiology Authors: Germaine Loo, Chieh‐Yang Koo, Junjie Zhang, Ruogu Li, Rithi Sethi, Thun‐How Ong, Bee‐Choo Tai, Chi‐Hang Lee Tags: Trial Designs Source Type: research