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Condition: Chronic Obstructive Pulmonary

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Total 1274 results found since Jan 2013.

Importance of Considering Competing Risks in Time-to-Event Analyses: Application to Stroke Risk in a Retrospective Cohort Study of Elderly Patients With Atrial Fibrillation Original Articles
Conclusions: The incidence of death without stroke was 9-fold higher than that of stroke, leading to biased estimates of stroke risk with traditional time-to-event methods. Statistical methods that appropriately account for competing risks should be used to mitigate this bias.
Source: Circulation: Cardiovascular Quality and Outcomes - July 11, 2018 Category: Cardiology Authors: Abdel-Qadir, H., Fang, J., Lee, D. S., Tu, J. V., Amir, E., Austin, P. C., Anderson, G. M. Tags: Atrial Fibrillation, Epidemiology, Primary Prevention, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Cerebrovascular Accidents During Mechanical Circulatory Support Clinical Sciences
Conclusions—Stroke is a major cause of morbidity and mortality in patients on LVAD support. Chronic obstructive pulmonary disease increases the risk of ischemic stroke, whereas dialysis may increase the risk of hemorrhagic stroke. Although any stroke increases mortality, post-LVAD hemorrhagic stroke was associated with higher mortality compared with ischemic stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Saef Izzy, Daniel B. Rubin, Firas S. Ahmed, Feras Akbik, Simone Renault, Katelyn W. Sylvester, Henrikas Vaitkevicius, Jennifer A. Smallwood, Michael M. Givertz, Steven K. Feske Tags: Heart Failure, Complications, Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Lifetime direct costs of stroke for indigenous patients adjusted for comorbidities
Conclusions: The costs of stroke for indigenous people and patients with different comorbidities are substantial and an integrated prevention strategy is needed.
Source: Neurology - July 31, 2016 Category: Neurology Authors: Zhao, Y., Condon, J., Lawton, P., He, V., Cadilhac, D. A. Tags: Cost effectiveness/economic, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Increasing comorbidity and health services utilization in older adults with prior stroke
Conclusions: Our findings demonstrate the importance of community-based patient-centered care strategies for stroke survivors that address their range of health needs and prevent more costly acute care use.
Source: Neurology - November 13, 2016 Category: Neurology Authors: Gruneir, A., Griffith, L. E., Fisher, K., Panjwani, D., Gandhi, S., Sheng, L., Patterson, C., Gafni, A., Ploeg, J., Markle-Reid, M. Tags: All Health Services Research, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

A Phase IIB Clinical Trial of Normobaric Oxygen Therapy (NBO) in Acute Ischemic Stroke (AIS) (S02.001)
CONCLUSIONS: NBO did not affect NIHSS or infarct growth in this trial. The observed imbalance in deaths remains unexplained, but appears unrelated to NBO. Further studies are warranted.Supported by: NIH-NINDS.Disclosure: Dr. Singhal has received personal compensation as an expert witness in medicolegal cases involving stroke in young adults. Dr. Singhal's wife is an employee of Vertex Pharmaceuticals, Inc. Dr. Singhal has received research support from Pfizer and Photothera, Inc. Dr. On Behalf of Partners SPOTRIAS Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Singhal, A., on Behalf of Partners SPOTRIAS Investigators, Tags: S02 Acute Stroke Therapy Source Type: research

Right Heart Failure as a Risk for Stroke in Patients with Chronic Obstructive Pulmonary Disease: A Case-Control Study
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition characterized by complex lesions of the lungs and other organs as well as a progressive obstruction of the airway. In COPD patients, heart failure (HF) is associated with worse conditions such as inflammation, arterial stiffness, and increased risk mortality. However, the association of HF, COPD, and stroke are unclear; the examination of the role of HF, especially right HF, about increased risk of stroke in COPD patients has not been studied.
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2017 Category: Neurology Authors: Arturo Orea-Tejeda, Katya Bozada-Guti érrez, Juan Pineda-Juárez, Dulce González-Islas, Brenda Santellano-Juárez, Candace Keirns-Davies, Viridiana Peláez-Hernández, Rafael Hernández-Zenteno, Rocio Sánchez-Santillán, Carlos Cintora-Martínez Source Type: research

Long-term mortality in ischemic stroke patients with concomitant chronic obstructive pulmonary disease
This study aimed to compare long-term all-cause mortality in ischemic stroke patients with and without COPD.
Source: Journal of Stroke and Cerebrovascular Diseases - September 4, 2022 Category: Neurology Authors: Shreya Bavishi, Durgesh Chaudhary, Jiang Li, Sreelatha Naik, Vida Abedi, Ramin Zand Source Type: research

Chronic Obstructive Pulmonary Disease and the Risk of Stroke: the Rotterdam Study.
CONCLUSION: Our cohort study demonstrated a higher risk of both ischemic and hemorrhagic stroke in subjects with COPD, and revealed the importance of smoking as a shared risk factor. PMID: 26414484 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - September 28, 2015 Category: Respiratory Medicine Authors: Portegies ML, Lahousse L, Joos GF, Hofman A, Koudstaal PJ, Stricker BH, Brusselle GG, Ikram MA Tags: Am J Respir Crit Care Med Source Type: research

Assessing improvements in survival for stroke patients in the Northern Territory 1992?2013: a marginal structural analysis.
Conclusions Stroke survival has improved in the NT over the past two decades. The marginal structural models provide a powerful methodological tool that can be applied to hospital administrative data to assess changes in quality of care and the impact of interventions. What is known about the topic? Stroke-related mortality has fallen in the past 30 years in Australia. Indigenous Australians have much worse health outcomes than other Australians, including higher stroke incidence and mortality, but it is not known whether stroke survival has improved for Indigenous stroke patients. What does this paper add? This study meas...
Source: Australian Health Review - February 23, 2015 Category: Hospital Management Authors: Zhao Y, Condon J, You J, Guthridge S, He V Tags: Aust Health Rev Source Type: research

Impact of chronic inflammatory airway disease on stroke severity and long-term survival after ischemic stroke - a retrospective analysis
Conclusion: Co-existing CIAD showed no significant association with stroke severity at hospital admission and early mortality after ischemic stroke. CIAD was negatively associated with long-term survival after ischemic stroke.
Source: BMC Neurology - September 8, 2015 Category: Neurology Authors: Karl HaeuslerJuliane HermMaria KoniecznyUlrike GrittnerMitja LainscakMatthias EndresWolfram Doehner Source Type: research

Does CHA2DS2-VASc score predict ischaemic stroke in chronic obstructive pulmonary disease?
Chronic obstructive pulmonary disease (COPD) is associated with a high risk of ischaemic stroke.1 CHA2DS2-VASc score is recommended and is widely used for stroke risk stratification in atrial fibrillation (AF) patients,2 but it has been shown to be an independent predictor of thrombo-embolic events in patients without AF, as well.3 In this issue ofEuropace, Huet al. performed a retrospective cohort study in a very big case sample (1492 COPD patients with AF and 50  343 COPD patients without AF), and reported that COPD patients with a higher CHA2DS2-VASc score were more likely to develop ischaemic stroke whether or not AF...
Source: Europace - October 17, 2017 Category: Cardiology Source Type: research

Incidence of stroke and stroke subtypes in chronic obstructive pulmonary disease
Abstract It is uncertain whether the incidence of stroke is increased in patients with chronic obstructive pulmonary disease (COPD), and whether COPD is associated with all subtypes of stroke (i.e. ischemic stroke, intracerebral haemorrhage and subarachnoid haemorrhage). We evaluated the association between COPD and incidence of stroke in a nation-wide cohort study. All individuals between 40 and 84 years of age, hospitalised for COPD between 1987 and 2003 in Sweden were identified in the Swedish hospital discharge register. For each COPD patient (n = 103,419), one reference individual was randomly selected fro...
Source: European Journal of Epidemiology - December 28, 2015 Category: Epidemiology Source Type: research

Do We Need to Distinguish Thrombolysis and Nonthrombolysis Patients When Applying Stroke-Associated Pneumonia Predicting Scores? An External Validation from a 2-Center Database.
CONCLUSIONS The AIS-APS had the highest AUC and goodness of fit in our population. All 4 scores can be applied regardless of whether thrombolysis has been performed on patients. PMID: 32921786 [PubMed - in process]
Source: Medical Science Monitor - September 15, 2020 Category: Research Tags: Med Sci Monit Source Type: research

Intraoperative hypotension and perioperative acute ischemic stroke in patients having major elective non-cardiovascular non-neurological surgery
ConclusionOur analysis suggests that when MAP is less than 60  mmHg for more than 20 min, there is increased odds of acute ischemic stroke. Further studies are needed to determine what MAP should be targeted during surgery to optimize cerebral perfusion and limit ischemic stroke risk.
Source: Journal of Anesthesia - February 9, 2021 Category: Anesthesiology Source Type: research

Higher Mortality of Ischaemic Stroke Patients Hospitalized with COVID-19 Compared to Historical Controls
Conclusions: Ischaemic stroke patients with COVID-19 had significantly higher 60-day all-cause mortality compared to propensity score-matched historical controls (ischaemic stroke patients without COVID-19).Cerebrovasc Dis
Source: Cerebrovascular Diseases - March 26, 2021 Category: Neurology Source Type: research