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Fatal Staphylococcus Aureus Endocarditis Misdiagnosed as Multisystem Inflammatory Syndrome in Children
We present a case of a 10-year-old male with Staphylococcus aureus mitral endocarditis who was initially misdiagnosed with multisystem inflammatory syndrome associated with coronavirus disease 2019, with eventual fatal outcome due to brain hemorrhage after cardiac intervention. Our case differs from recent studies, in which microbleeds did not increase the risk of hemorrhagic stroke or global mortality risk.
Source: The Pediatric Infectious Disease Journal - January 19, 2022 Category: Infectious Diseases Tags: Brief Reports Source Type: research

Lactobacillus Endocarditis Complicated by Presumed Vertebral Osteomyelitis and Embolic Stroke
In this report, we describe a case in which a 47-year old man with no past medical history develops native aortic valve endocarditis complicated by embolic stroke and presumed lumbar vertebral osteomyelitis.
Source: Infectious Diseases in Clinical Practice - November 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Silent but Deadly: Legionella maceachernii: Causing Culture-Negative Bioprosthetic Mitral Valve Endocarditis Complicated by Stroke
We report the first case of bioprosthetic valve endocarditis due to Legionella maceachernii. This case highlights the importance of the use of DNA target sequencing to identify the cause of culture-negative endocarditis, as standard empiric therapy would not have covered the identified organism.
Source: Infectious Diseases in Clinical Practice - August 26, 2020 Category: Infectious Diseases Tags: Case Reports Source Type: research

A rare cause of infective endocarditis and stroke: filamentous vegetation due to Granulicatella adiacens
Source: International Journal of Infectious Diseases - June 2, 2020 Category: Infectious Diseases Authors: Christoffel J. Opperman, Jens Hitzeroth Tags: Medical Imagery Source Type: research

A Complicated Case of Haemophilus influenzae Endocarditis in an Adult
Bacterial causes for infective endocarditis have changed over the years, with Staphylococcus aureus now being the most common pathogen isolated. With the advent of routine childhood vaccinations, invasive infections caused by Haemophilus influenzae have become rare. We wish to report a case of infective endocarditis caused by H. influenzae that was complicated by meningitis, septic arthritis, and stroke.
Source: Infectious Diseases in Clinical Practice - April 24, 2020 Category: Infectious Diseases Tags: Case Reports Source Type: research

Infections causing stroke or stroke-like syndromes
ConclusionsStroke or stroke-like syndrome of infectious origin can be observed in an important proportion of case presenting with sensory-motor deficit of unknown origin; their accurate diagnosis has a considerable impact in terms of treatment choices and outcome.
Source: Infection - March 31, 2020 Category: Infectious Diseases Source Type: research

Left-sided infective endocarditis in persons who inject drugs
ConclusionsLSIE in PWID is not uncommon. Compared to non-LSIE in PWID, valve surgery is more common and mortality is higher. For reasons that are unclear, stroke is more frequent in LSIE in PWID than in non-PWID with LSIE but mortality is no different.
Source: Infection - February 24, 2020 Category: Infectious Diseases Source Type: research

A classic and fatal case of Streptococcus mutans subacute bacterial endocarditis; A now potentially underappreciated disease
We describe a patient found to have Streptococcus mutans subacute bacterial endocarditis, who presented with classic risk factors and findings, and who died shortly after presentation due to hemorrhagic conversion of an embolic stroke in the setting of anticoagulation. It is critical that all cases of streptococcal bacteremia be appropriately evaluated and treated, and that Streptococcus spp. not ever be routinely considered a blood culture ‘contaminant’.
Source: IDCases - January 12, 2020 Category: Infectious Diseases Source Type: research

Aspergillus fumigatus endocarditis in a splenectomized patient with no risk factors
Publication date: Available online 9 January 2020Source: IDCasesAuthor(s): Abhimanyu Aggarwal,, Karen Hogan,, Armando Paez,AbstractAspergillus endocarditis is a rare cause of culture-negative fungal endocarditis, after Candida endocarditis. Typical risk factors include intravenous drug use, immunosuppression, prior cardiac surgery or presence of prosthetic heart valves, hematopoietic stem cell or solid organ transplantation. Common presentations include signs and symptoms consistent with endocarditis but with negative bacterial blood cultures. Here, we present a case report of a 49-year-old male without known risk factors ...
Source: IDCases - January 9, 2020 Category: Infectious Diseases Source Type: research

Infectious causes of stroke
Purpose of review Stroke continuous to be a leading cause of debility in the world. Infections have been associated with stroke, but are not considered as directly causal, and so they are not often included in the traditional stroke workup and management. They are especially important in patients with stroke of undetermined etiology, and in certain patient populations, such as young patients without traditional risk factors, and immunocompromised patients. Recent findings There has been strong evidence for infectious conditions, such as endocarditis, and pathogens, such as varicella zoster in stroke causation, and mor...
Source: Current Opinion in Infectious Diseases - April 26, 2019 Category: Infectious Diseases Tags: CNS INFECTIONS: Edited by Adarsh Bhimraj Source Type: research

Fatal Neisseria macacae infective endocarditis: first report
We present here the first case ofN. macacae infective endocarditis in a 65-year-old man with a native aortic valve infection complicated by a peri-aortic abscess. N. macacae was isolated from blood culture and was found on the cardiac valve using 16S rDNA detection. Despite an appropriate antibiotic therapy, and aortic homograft replacement, and mitral repair, the patient died 4  days after surgery from a massive hemorrhagic stroke.
Source: Infection - January 27, 2017 Category: Infectious Diseases Source Type: research

HACEK endocarditis: a review.
Authors: Sharara SL, Tayyar R, Kanafani ZA, Kanj SS Abstract The HACEK group referring to Haemophilus spp., Aggregatibacter actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella kingae, is a rare cause of infective endocarditis. It causes the majority of Gram-negative endocarditis cases. It has a higher risk of embolization and stroke and tends to affect younger individuals when compared to non-HACEK endocarditis. The modified Duke criteria for diagnosing infective endocarditis apply to HACEK endocarditis but the HACEK group tends to have larger vegetations on echocardiography. Furthermo...
Source: Expert Review of Anti-Infective Therapy - April 30, 2016 Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research

Native Valve Emphysematous Endocarditis Caused by Finegoldia magna in a Novel Pathogenic Role
We describe a case of native valve emphysematous endocarditis presenting with stroke and ultimately leading to left ventricular rupture and the patient's untimely death. Premortem blood cultures and postmortem pathologic and histologic examination yielded Finegoldia magna (formerly Peptostreptococcus magnus) in a novel pathogenic role. As detection methods continue to improve for Finegoldia magna, it is important to increase awareness of the pathogenic role of this organism.
Source: Infectious Diseases in Clinical Practice - December 28, 2015 Category: Infectious Diseases Tags: Case Reports Source Type: research

Profile of infective endocarditis observed from 2003 - 2010 in a single center in Italy
Conclusion: S. aureus emerged as the leading causative organism of IE in a University hospital in northern Italy. Our study confirmed the high in-hospital mortality of IE, particularly if health-care associated, and the protective role of surgery.
Source: BMC Infectious Diseases - November 15, 2013 Category: Infectious Diseases Authors: Laurenzia FerrarisLaura MilazzoDavide RicaboniCristina MazzaliGiovanna OrlandoGiuliano RizzardiniMarco CicardiFerdinando RaimondiLoredana TocalliAlessandro CialfiPaolo VanelliMassimo GalliCarlo AntonaSpinello Antinori Source Type: research