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Condition: Endocarditis

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Total 767 results found since Jan 2013.

Heartbeat: knowledge gaps for non-bacterial thrombotic endocarditis
Non-bacterial thrombotic endocarditis (NBTE) contributes to adverse outcomes in patients with systemic inflammatory conditions, antiphospholipid syndrome or advanced malignancy (figure 1). Diagnosis is challenging and there is little data to guide prevention of adverse events, particularly stroke. In this issue of Heart, Quintero-Martinez and colleagues1 report the clinical characteristics and outcomes in 48 adults with NBTE identified at the Mayo Clinic over a 7 year period. Most patients (75%) were women with a mean age of 60 years and most cases were associated with malignancy (52%) or a systemic inflammatory disease (3...
Source: Heart - September 26, 2022 Category: Cardiology Authors: Otto, C. M. Tags: Highlights from this issue Source Type: research

Contemporary demographics, diagnostics and outcomes in non-bacterial thrombotic endocarditis
Conclusions NBTE was more prevalent in females and embolic complications were the most frequent clinical finding. Overall, patients with NBTE had a poor prognosis, particularly in those with lung cancer or metastatic tumours. Further studies in patients with NBTE are needed given its morbidity and mortality.
Source: Heart - September 26, 2022 Category: Cardiology Authors: Quintero-Martinez, J. A., Hindy, J.-R., El Zein, S., Michelena, H. I., Nkomo, V. T., DeSimone, D. C., Baddour, L. M. Tags: Valvular heart disease, Editor's choice Source Type: research

Thrombectomy in special populations: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee
Background The purpose of this guideline is to summarize the data available for performing mechanical thrombectomy (MT) for emergent large vessel occlusion (ELVO) stroke in special populations not typically included in large randomized controlled clinical trials, including children, the elderly, pregnant women, patients who have recently undergone surgery, and patients with thrombocytopenia, collagen vascular disorders, and endocarditis. Methods We performed a literature review for studies examining the indications, efficacy, and outcomes for patients undergoing MT for ischemic stroke aged <18 years and >80 years, p...
Source: Journal of NeuroInterventional Surgery - September 14, 2022 Category: Neurosurgery Authors: Al-Mufti, F., Schirmer, C. M., Starke, R. M., Chaudhary, N., De Leacy, R., Tjoumakaris, S. I., Haranhalli, N., Abecassis, I. J., Amuluru, K., Bulsara, K. R., Hetts, S. W., On behalf of the SNIS Standards and Guidelines Committee and SNIS Board of Director Tags: Standards Source Type: research

Temporal trends in incidence, patient characteristics, microbiology and in-hospital mortality in patients with infective endocarditis: a contemporary analysis of 86,469 cases between 2007 and 2019
ConclusionsIn this contemporary cohort, incidence of IE increased over time and in-hospital mortality remained high (~  15%). Whilestaphylococcus andstreptococcus were the predominant microorganisms, bacteremia withstaphylococcus and Gram-negative pathogens were associated with higher likelihood of in-hospital mortality. Our results highlight the need for new preventive strategies and interventions in patients with IE.Graphical abstractInfective endocarditis in Germany.BCNIE blood culture-negative infective endocarditis,IE infective endocarditis
Source: Clinical Research in Cardiology - September 12, 2022 Category: Cardiology Source Type: research

A Cryptogenic Stroke Associated With Infective Endocarditis and Antiphospholipid Antibody Syndrome: Case Report and Literature Review
ConclusionA considerable challenge for physicians is evaluating all the signs suggestive of embolic sources in acute stroke and identifying the primary etiology when there are multiple causes. Early diagnosis and surgical intervention for bicuspid aortic valve (BAV) vegetation complicated by acute stroke may yield favorable clinical results.
Source: Frontiers in Neurology - July 25, 2022 Category: Neurology Source Type: research

E-124 Timing surgery and hemorrhagic complications in endocarditis with concomitant cerebral complications
ConclusionsPatients with radiographic evidence of ischemic stroke from septic emboli can safely undergo valvular surgery for IE without increased risk of symptomatic hemorrhage. We advocate for baseline CTA screening to evaluate for IIA in patients who present with a primary diagnosis of IE and propose a management algorithm.Disclosures B. Lucke-Wold: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Lucke-Wold, B. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-136 Morphology of mycotic aneurysms and outcomes
ConclusionPatients with secured mycotic aneurysms are less likely to have in-hospital mortality from postoperative hemorrhage and more likely to have better outcomes upon discharge. This snapshot study warrants further investigation to determine the optimal safe timing between securing IIAs to valvular surgery.Disclosures N. Krothapalli: None. M. Tsikvadze: None. N. Akram: None. A. Elmashad: None. N. Desai: None. A. Tunguturi: None. T. Mehta: None. S. Patel: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Krothapalli, N., Tsikvadze, M., Akram, N., Elmashad, A., Desai, N., Tunguturi, A., Mehta, T., Patel, S. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-164 Recurrent strokes as the initial presentation of colorectal adenocarcinoma
ConclusionCryptogenic strokes in patients with cancer are cardioembolic manifestations of cancer-mediated hypercoagulability such as NBTE, which consists of sterile, platelet-fibrin vegetations on cardiac valves. The mechanism of thromboembolism in patients with cancer is based on the interaction between tumor cells and leukocytes, which creates a thrombogenic vascular lining and induces the release of substances that activate the coagulation cascade. The diagnosis of NBTE should depend on the distribution of occluded vessels, identification of thrombus, and exclusion of other possible causes such as infective endocarditis...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Babici, D., Phillip Johansen, P., Rodriguez-Hernandez, A., Sommerville, S., Snelling, B., Miller, T. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Causes of ischemic stroke in young adults versus non-young adults: A multicenter hospital-based observational study
CONCLUSIONS: Certain embolic sources and uncommon causes may be etiologically important causes of ischemic stroke in young adults. However, the contribution of conventional vascular risk factors and lifestyle-related risk factors is not negligible with advancing age, even in young adults.PMID:35830430 | DOI:10.1371/journal.pone.0268481
Source: Atherosclerosis - July 13, 2022 Category: Cardiology Authors: Yuichiro Ohya Ryu Matsuo Noriko Sato Fumi Irie Kuniyuki Nakamura Yoshinobu Wakisaka Tetsuro Ago Masahiro Kamouchi Takanari Kitazono Investigators for Fukuoka Stroke Registry Source Type: research

Neurological Complications and Clinical Outcomes of Infective Endocarditis
The aim of this study is to explore the clinical features associated with neurological complications of infective endocarditis (IE) and to assess the impact of neurological complications on clinical outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - July 4, 2022 Category: Neurology Authors: Alvin S. Das, Morgan McKeown, Stephanie A. Jordan, Karen Li, Robert W. Regenhardt, Steven K. Feske Source Type: research

Severe Libman –Sacks endocarditis complicating antiphospholipid syndrome: a retrospective analysis of 23 operated cases
ConclusionSevere HVD leading to surgery was strongly associated with thrombotic APS, especially arterial phenotypes. Half of the reported patients presented cerebral stroke complicating the HVD. Valvular surgery carried a significant risk of CAPS.
Source: Rheumatology - June 10, 2022 Category: Rheumatology Source Type: research

Ten-Year Long-Term Analysis of Mechanical and Biological Aortic Valve Replacement
CONCLUSION: After isolated AVR with MP and BP, 10-year long-term outcomes were comparable in the reported single-center cohort. MP can still be implanted safely without a disadvantage as regards long-term survival.PMID:35667381 | DOI:10.1055/s-0042-1744477
Source: The Thoracic and Cardiovascular Surgeon - June 6, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Kaveh Eghbalzadeh Elmar W Kuhn Stephen Gerfer Ilija Djordjevic Parwis Rahmanian Navid Mader Thorsten C W Wahlers Source Type: research