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Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach
AbstractDue to the reactive medical approach applied to disease management, stroke has reached an epidemic scale worldwide. In 2019, the global stroke prevalence was 101.5 million people, wherefrom 77.2 million (about 76%) suffered from ischemic stroke; 20.7 and 8.4 million suffered from intracerebral and subarachnoid haemorrhage, respectively. Globally in the year 2019 — 3.3, 2.9 and 0.4 million individuals died of ischemic stroke, intracerebral and subarachnoid haemorrhage, respectively. During the last three decades, the absolute number of cases increased substantially. The current prevalence of stroke is 110 million ...
Source: EPMA Journal - November 17, 2022 Category: International Medicine & Public Health Source Type: research

Focused ultrasound opening brain to previously impossible treatments
(University of Virginia Health System) Focused ultrasound, the researchers hope, could revolutionize treatment for conditions from Alzheimer's to epilepsy to brain tumors -- and even help repair the devastating damage caused by stroke.
Source: EurekAlert! - Medicine and Health - May 6, 2020 Category: International Medicine & Public Health Source Type: news

Stroke: Macrophages migrate from the blood
(University of Bonn) Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center (USA) succeeded in visualizing macrophages that were formed in the bone marrow. This technology enabled to observe that shortly after a stroke, numerous macrophages that had migrated from the blood begin to attack dead and adjacent healthy brain tissue.
Source: EurekAlert! - Medicine and Health - February 11, 2020 Category: International Medicine & Public Health Source Type: news

Age-specific association between blood pressure and vascular and non-vascular chronic diseases in 0·5 million adults in China: a prospective cohort study
Publication date: June 2018Source: The Lancet Global Health, Volume 6, Issue 6Author(s): Ben Lacey, Sarah Lewington, Robert Clarke, Xiang Ling Kong, Yiping Chen, Yu Guo, Ling Yang, Derrick Bennett, Fiona Bragg, Zheng Bian, Shaojie Wang, Hua Zhang, Junshi Chen, Robin G Walters, Rory Collins, Richard Peto, Liming Li, Zhengming Chen, Junshi Chen, Zhengming ChenSummaryBackgroundThe age-specific association between blood pressure and vascular disease has been studied mostly in high-income countries, and before the widespread use of brain imaging for diagnosis of the main stroke types (ischaemic stroke and intracerebral haemorrh...
Source: The Lancet Global Health - July 10, 2018 Category: International Medicine & Public Health Source Type: research

Age-specific association between blood pressure and vascular and non-vascular chronic diseases in 0 ·5 million adults in China: a prospective cohort study
Publication date: June 2018 Source:The Lancet Global Health, Volume 6, Issue 6 Author(s): Ben Lacey, Sarah Lewington, Robert Clarke, Xiang Ling Kong, Yiping Chen, Yu Guo, Ling Yang, Derrick Bennett, Fiona Bragg, Zheng Bian, Shaojie Wang, Hua Zhang, Junshi Chen, Robin G Walters, Rory Collins, Richard Peto, Liming Li, Zhengming Chen Background The age-specific association between blood pressure and vascular disease has been studied mostly in high-income countries, and before the widespread use of brain imaging for diagnosis of the main stroke types (ischaemic stroke and intracerebral haemorrhage). We aimed to investigate th...
Source: The Lancet Global Health - May 15, 2018 Category: International Medicine & Public Health Source Type: research

Mortality Disparities in Racial/Ethnic Minority Groups in the Veterans Health Administration: An Evidence Review and Map.
CONCLUSIONS: Although the VHA's equal access health care system has reduced many racial/ethnic mortality disparities present in the private sector, our review identified mortality disparities that have persisted mainly for Black veterans in several clinical areas. However, because most mortality disparities were supported by single studies with imprecise findings, we could not draw strong conclusions about this evidence. More disparities research is needed for American Indian and Alaska Native, Asian, and Hispanic veterans overall and for more of the largest life expectancy gaps. Public Health Implications. Because of the ...
Source: American Journal of Public Health - February 9, 2018 Category: International Medicine & Public Health Authors: Peterson K, Anderson J, Boundy E, Ferguson L, McCleery E, Waldrip K Tags: Am J Public Health Source Type: research

Profiles of executive function across children with distinct brain disorders: traumatic brain injury, stroke, and brain tumor - Araujo GC, Antonini TN, Anderson V, Vannatta KA, Salley CG, Bigler ED, Taylor HG, Gerhardt C, Rubin K, Dennis M, Lo W, Mackay MT, Gordon A, Hajek Koterba C, Gomes A, Greenham M, Owen Yeates K.
This study examined whether children with distinct brain disorders show different profiles of strengths and weaknesses in executive functions, and differ from children without brain disorder. METHODS: Participants were children with tra...
Source: SafetyLit - May 19, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Evaluating overweight and obesity prevalence in survivors of childhood brain tumors: a systematic review protocol
The objective of this systematic review is to examine the prevalence of overweight and obesity in SCBT. The secondary aim of this review is to evaluate whether SCBT have higher adiposity compared to the general population.MethodsSearches will be conducted in MEDLINE, CINAHL, EMBASE, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, PubMed, and Database of Abstracts of Reviews of Effect. For gray literature, we will search ProQuest Dissertations and Theses A&I and Web of Science. Two reviewers will independently screen all articles against predetermined eligibility criteria and com...
Source: Systematic Reviews - March 2, 2017 Category: Global & Universal Source Type: research

Intra-hospital correlations among 30-day mortality rates in 18 different clinical and surgical settings
Conclusions</div>The variability in 30-day mortality rates at hospital level and the correlation between risk mortality rates suggest that there may be common hospital-wide factors influencing short-term mortality.</span>
Source: International Journal for Quality in Health Care - January 31, 2017 Category: Global & Universal Source Type: research

Toxic Air – The ‘Invisible Killer’ that Stifles 300 Million Children
On 24 October 2016 in Yenagoa, Bayelsa State, Nigeria, children pass in front of a flame fed by waste and rubber materials in order to make Kanda, a type of smoked meat, at an abattoir. Photo: UNICEF/Tanya BindraBy Baher KamalROME, Nov 1 2016 (IPS)About 300 million children in the world are living in areas with outdoor air so toxic – six or more times higher than international pollution guidelines – that it can cause serious health damage, including harming their brain development. This shocking finding has just been revealed by the United Nations Children’s Fund (UNICEF), in a new report — ‘Clear the...
Source: IPS Inter Press Service - Health - November 1, 2016 Category: Global & Universal Authors: Baher Kamal Tags: Climate Change Featured Global Headlines Health Humanitarian Emergencies IPS UN: Inside the Glasshouse Poverty & SDGs Source Type: news

Men with nonapnea sleep disorders have a high risk of developing subsequent epilepsy: A nationwide population-based cohort study
Conclusion This study indicated that patients with NSDs have a higher risk of developing epilepsy and that the risk is much higher among men and older patients. These findings suggest that NSDs constitute a predisposing, possibly independent factor for developing subsequent epilepsy in adulthood.
Source: Preventive Medicine - August 28, 2016 Category: Global & Universal Source Type: research

Current status of biomarker research in neurology
Abstract Neurology is one of the typical disciplines where personalized medicine has been recently becoming an important part of clinical practice. In this article, the brief overview and a number of examples of the use of biomarkers and personalized medicine in neurology are described. The various issues in neurology are described in relation to the personalized medicine and diagnostic, prognostic as well as predictive blood and cerebrospinal fluid biomarkers. Such neurological domains discussed in this work are neuro-oncology and primary brain tumors glioblastoma and oligodendroglioma, cerebrovascular diseases ...
Source: EPMA Journal - July 3, 2016 Category: Global & Universal Source Type: research

EPMA-World Congress 2015
Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of ...
Source: EPMA Journal - May 8, 2016 Category: Global & Universal Source Type: research

Neurosurgery researchers receive NIH grants to study Parkinson's, stroke, & brain cancer
(University Hospitals Case Medical Center) Researchers from the Department of Neurological Surgery at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center recently received multi-year, multi-million dollar grants from the National Institutes of Health for studies in Parkinson's disease, stroke, and brain cancer.
Source: EurekAlert! - Medicine and Health - December 7, 2015 Category: Global & Universal Source Type: news

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