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Total 206 results found since Jan 2013.

Adiposity and risk of ischaemic and haemorrhagic stroke in 0·5 million Chinese men and women: a prospective cohort study
Publication date: June 2018Source: The Lancet Global Health, Volume 6, Issue 6Author(s): Zhengming Chen, Andri Iona, Sarah Parish, Yiping Chen, Yu Guo, Fiona Bragg, Ling Yang, Zheng Bian, Michael V Holmes, Sarah Lewington, Ben Lacey, Ruqin Gao, Fang Liu, Zengzhi Zhang, Junshi Chen, Robin G Walters, Rory Collins, Robert Clarke, Richard Peto, Liming LiSummaryBackgroundChina has high stroke rates despite the population being relatively lean. Uncertainty persists about the relevance of adiposity to risk of stroke types. We aimed to assess the associations of adiposity with incidence of stroke types and effect mediation by bloo...
Source: The Lancet Global Health - July 5, 2018 Category: International Medicine & Public Health Source Type: research

Association between insomnia and type 2 diabetes mellitus in Han Chinese individuals in Shandong Province, China.
CONCLUSIONS: This study suggests that insomnia is independently and significantly associated with diabetes mellitus in the northern Chinese population, especially in the 40-59-year-old age group and in males. PMID: 29961182 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - June 30, 2018 Category: Sleep Medicine Authors: Zhang Y, Lin Y, Zhang J, Li L, Liu X, Wang T, Gao Z Tags: Sleep Breath Source Type: research

Association between insomnia and type 2 diabetes mellitus in Han Chinese individuals in Shandong Province, China
ConclusionsThis study suggests that insomnia is independently and significantly associated with diabetes mellitus in the northern Chinese population, especially in the 40 –59-year-old age group and in males.
Source: Sleep and Breathing - June 30, 2018 Category: Respiratory Medicine Source Type: research

Twenty-year epidemiologic study on LDL-C levels in relation to the risks of atherosclerotic event, hemorrhagic stroke, and cancer death among young and middle-aged population in China
Lowering elevated low-density lipoprotein cholesterol (LDL-C) levels is a key strategy in primary prevention of atherosclerotic cardiovascular disease (ASCVD), but the optimal LDL-C level is not well established in Chinese.
Source: Journal of Clinical Lipidology - June 26, 2018 Category: Lipidology Authors: Xingguang Zhang, Jing Liu, Miao Wang, Yue Qi, Jiayi Sun, Jun Liu, Ying Wang, Yongchen Hao, Yan Li, Mengge Zhou, Dong Zhao Tags: Original Article Source Type: research

Twenty-year epidemiologic study on LDL cholesterol levels in relation to the risks of atherosclerotic event, hemorrhagic stroke, and cancer death among young and middle-aged population in China
Lowering elevated low-density lipoprotein cholesterol (LDL-C) level is a key strategy in primary prevention of atherosclerotic cardiovascular disease (ASCVD), but the optimal LDL-C level is not well established in Chinese.
Source: Journal of Clinical Lipidology - June 26, 2018 Category: Lipidology Authors: Xingguang Zhang, Jing Liu, Miao Wang, Yue Qi, Jiayi Sun, Jun Liu, Ying Wang, Yongchen Hao, Yan Li, Mengge Zhou, Dong Zhao Tags: Original Research Source Type: research

Unique MicroRNAs Signature of Lymphocyte of Yang and Yin Syndromes in Acute Ischemic Stroke Patients
ConclusionThese results offered insight into the molecular basis underlying the different pathogenesis of yang or yin syndrome, providing clues for the individualized therapeutic strategies of acute ischemic stroke.
Source: Chinese Journal of Integrative Medicine - June 20, 2018 Category: Internal Medicine Source Type: research

Ambient air pollution of particles and gas pollutants, and the predicted health risks from long-term exposure to PM2.5 in Zhejiang province, China.
Abstract In recent years, ambient air has been severely contaminated by particulate matters (PMs) and some gas pollutants (nitrogen dioxide (NO2) and sulfur dioxide (SO2)) in China, and many studies have demonstrated that exposure to these pollutants can induce great adverse impacts on human health. The concentrations of the pollutants were much higher in winter than those in summer, and the average concentrations in this studied area were lower than those in northern China. In the comparison between high-resolution emission inventory and spatial distribution of PM2.5, significant positive linear correlation was f...
Source: Environmental Science and Pollution Research International - June 6, 2018 Category: Environmental Health Authors: Chen Y, Zang L, Du W, Xu D, Shen G, Zhang Q, Zou Q, Chen J, Zhao M, Yao D Tags: Environ Sci Pollut Res Int Source Type: research

An Egg A Day Might Reduce Your Risk Of Heart Disease, Study Says
In this study however, they didn’t assess the risk of developing diabetes, which may be because diabetes is a newer disease in the Chinese population and there is not good documentation of who has it,” Richard said. Still, she noted, “this will be very important data for helping develop dietary prevention guidelines in China.” Cardiovascular disease, which takes the lives of 17.7 million people every year, is the leading cause of death and disability worldwide, according to the World Health Organization. Cardiovascular disease causes nearly a third — 31% — of all global deaths each year....
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 22, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Eggs Heart Disease Local TV Source Type: news

Characteristics of Ventricular Function in Pulmonary Hypertension Patients 
with Different Shape of Interventricular Septum:
Preliminary Study with Cardiac Magnetic Resonance Imaging
Background and objective To study the characteristics of ventricular function in Pulmonary Hypertension (PH) Patients with different shape of Interventricular Septum (IVS) by cardiac magnetic resonance (CMR). Methods 36 PH patients diagnosed by right heart catheterization accepted CMR. According to the morphology of IVS, the patients were divided into two groups: the non-deformation group (10 patients) and the deformation group (26 patients). The ventricular function parameters were as follows: RV and LV end-diastolic volume index (EDVI), end-systolic volume index (ESVI), stroke volume index (SVI), cardiac index (CI), ejec...
Source: Chinese Journal of Lung Cancer - May 16, 2018 Category: Cancer & Oncology Source Type: research

Adiposity and risk of ischaemic and haemorrhagic stroke in 0 ·5 million Chinese men and women: a prospective cohort study
Publication date: June 2018 Source:The Lancet Global Health, Volume 6, Issue 6 Author(s): Zhengming Chen, Andri Iona, Sarah Parish, Yiping Chen, Yu Guo, Fiona Bragg, Ling Yang, Zheng Bian, Michael V Holmes, Sarah Lewington, Ben Lacey, Ruqin Gao, Fang Liu, Zengzhi Zhang, Junshi Chen, Robin G Walters, Rory Collins, Robert Clarke, Richard Peto, Liming Li Background China has high stroke rates despite the population being relatively lean. Uncertainty persists about the relevance of adiposity to risk of stroke types. We aimed to assess the associations of adiposity with incidence of stroke types and effect mediation by blood p...
Source: The Lancet Global Health - May 15, 2018 Category: International Medicine & Public Health Source Type: research

Age-specific association between blood pressure and vascular and non-vascular chronic diseases in 0 ·5 million adults in China: a prospective cohort study
Publication date: June 2018 Source:The Lancet Global Health, Volume 6, Issue 6 Author(s): Ben Lacey, Sarah Lewington, Robert Clarke, Xiang Ling Kong, Yiping Chen, Yu Guo, Ling Yang, Derrick Bennett, Fiona Bragg, Zheng Bian, Shaojie Wang, Hua Zhang, Junshi Chen, Robin G Walters, Rory Collins, Richard Peto, Liming Li, Zhengming Chen Background The age-specific association between blood pressure and vascular disease has been studied mostly in high-income countries, and before the widespread use of brain imaging for diagnosis of the main stroke types (ischaemic stroke and intracerebral haemorrhage). We aimed to investigate th...
Source: The Lancet Global Health - May 15, 2018 Category: International Medicine & Public Health Source Type: research

High SBP trajectories are associated with risk of all-cause death in general Chinese population
Conclusion: High SBP trajectories are independent risk factors for all-cause death. Our findings suggest increasing SBP trajectories within the currently designated ‘normal’ range may still increase risk of all-cause death.
Source: Journal of Hypertension - May 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research

Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China
Objectives: We aimed to prospectively examine the associations of total, domain-specific, and intensity-specific physical activity with all-cause and cardiovascular mortality among Chinese hypertensive adults. Methods: We performed a prospective cohort study in 150 391 hypertensive participants aged 30–79 years from the China Kadoorie Biobank study of 512 891 participants recruited from 10 diverse areas across China during 2004–2008. Participants with heart disease, stroke, chronic obstructive pulmonary disease, and cancer at baseline were excluded. Results: During 1069 863 person-years of follow-up (medi...
Source: Journal of Hypertension - March 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Lifestyle Source Type: research

Pure mechanistic analysis of additive neuroprotective effects between baicalin and jasminoidin in ischemic stroke mice.
In this study we used transcriptome analysis to explore the pure therapeutic mechanisms of BA, JA and their combination (BJ) contributing to phenotype variation and reversal of pathological processes. Mice with middle cerebral artery obstruction were treated with BA, JA, their combination (BJ), or concha margaritifera (CM). Cerebral infarct volume was examined to determine the effect of these compounds on phenotype. Using the hippocampus microarray and ingenuity pathway analysis (IPA) software, we exacted the differentially expressed genes, networks, pathways, and functions in positive-phenotype groups (BA, JA and BJ) by c...
Source: Acta Pharmacologica Sinica - January 18, 2018 Category: Drugs & Pharmacology Authors: Wang PQ, Liu Q, Xu WJ, Yu YN, Zhang YY, Li B, Liu J, Wang Z Tags: Acta Pharmacol Sin Source Type: research

Prospective Study of Fasting Blood Glucose and Intracerebral Hemorrhagic Risk Clinical Sciences
The objective of the current study was to examine the potential impact of long-term fasting blood glucose concentration on subsequent risk of ICH.Methods—This prospective study included 96 110 participants of the Kailuan study, living in Kailuan community, Tangshan city, China, who were free of cardiovascular diseases and cancer at baseline (2006). Fasting blood glucose concentration was measured in 2006, 2008, 2010, and 2012. Updated cumulative average fasting blood glucose concentration was used as primary exposure of the current study. Incident ICH from 2006 to 2015 was confirmed by review of medical records.Results...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Cheng Jin, Guohong Li, Kathryn M. Rexrode, Mahmut E. Gurol, Xiaodong Yuan, Ying Hui, Chunyu Ruan, Anand Vaidya, Yanxiu Wang, Shouling Wu, Xiang Gao Tags: Cardiovascular Disease, Diabetes, Type 2, Epidemiology, Risk Factors, Intracranial Hemorrhage Original Contributions Source Type: research