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Specialty: Cardiology

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Total 24457 results found since Jan 2013.

Multimodal investigation reveals the neuroprotective mechanism of Angong Niuhuang pill for intracerebral hemorrhage: Converging bioinformatics, network pharmacology, and experimental validation
CONCLUSION: The results of the study combined with virtual screening and experimental validation showed that ANP has an important contribution in protecting the brain from neuronal damage by regulating the pathways of inflammation and pyroptosis, laying the foundation and innovative ideas for future studies.PMID:37633621 | DOI:10.1016/j.jep.2023.117045
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Jiawei Zhou Tianlin Jiang Jiahua Wang Weilan Wu Xiaochun Duan Huiyun Jiang Zhiyun Jiao Xiaohong Wang Source Type: research

Imaging Carotid Plaque Inflammation Using Positron Emission Tomography: Emerging Role in Clinical Stroke Care, Research Applications, and Future Directions
Cells. 2023 Aug 15;12(16):2073. doi: 10.3390/cells12162073.ABSTRACTAtherosclerosis is a chronic systemic inflammatory condition of the vasculature and a leading cause of stroke. Luminal stenosis severity is an important factor in determining vascular risk. Conventional imaging modalities, such as angiography or duplex ultrasonography, are used to quantify stenosis severity and inform clinical care but provide limited information on plaque biology. Inflammatory processes are central to atherosclerotic plaque progression and destabilization. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a validated techn...
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: John J McCabe Nicholas R Evans Sarah Gorey Shiv Bhakta James H F Rudd Peter J Kelly Source Type: research

The Role of the Low-Density Lipoprotein/High-Density Lipoprotein Cholesterol Ratio as an Atherogenic Risk Factor in Young Adults with Ischemic Stroke: A Case-Control Study
This study investigated the TC/HDL-C ratio and the LDL-C/HDL-C ratio, which may be more specific and common lipid parameters in young patients with ischemic stroke. This study aimed to demonstrate the sensitivity and specificity of TC/HDL-C and LDL-C/HDL-C ratios as atherogenic markers for young adult ischemic strokes. This trial was conducted as a retrospective case-control study. A total of 123 patients (patient group) and 86 healthy individuals (control group) aged 18-50 years were randomly selected from four different hospitals. Lipid parameters and TC/HDL-C and LDL-C/HDL-C ratios were compared between these two groups...
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Sibel Ciplak Ahmet Adiguzel Yusuf Ziya Deniz Melike Aba Unal Ozturk Source Type: research

Insulin resistance estimated by estimated glucose disposal rate predicts outcomes in acute ischemic stroke patients
In this study, we...
Source: Cardiovascular Diabetology - August 26, 2023 Category: Cardiology Authors: Zhengzhao Lu, Yunyun Xiong, Xueyan Feng, Kaixuan Yang, Hongqiu Gu, Xingquan Zhao, Xia Meng and Yongjun Wang Tags: Research Source Type: research

Prevalence and Outcomes of Patients With Acute Ischemic Stroke and Concomitant Non –ST-Elevation Myocardial Infarction (Results from the National Inpatient Sample 2016 to 2019)
We examined hospitalized patients with acute ischemic stroke and a concomitant NSTEMI diagnosis who were included in the National Inpatient Sample 2016 to 2019. Acute ischemic stroke and NSTEMI were defined by using the Inter national Classification of Diseases, Tenth Revision codes. Patients with ST-elevation MI were excluded.
Source: The American Journal of Cardiology - August 26, 2023 Category: Cardiology Authors: Shivani Mehta, Roxana Mehran, Shahzad Hassan, Jasmeet Kaur, Anupam Sule, Camelia Arsene, Geetha Krishnamoorthy, Moyses Szklo Source Type: research

Outcomes of Concomitant Coronary Artery Bypass Grafting in Patients With Infective Endocarditis: A Systematic Review and Meta-Analysis
It is current practice to perform concomitant coronary artery bypass grafting (CABG) in patients with infective endocarditis who have relevant coronary artery disease. However, CABG may add complexity to the operation. We performed a systematic review and a meta-analysis of studies that presented outcomes from patients who underwent valve surgery because of infective endocarditis with or without concomitant CABG. Three databases were assessed. Perioperative mortality was the primary outcome. Long-term mortality and postoperative stroke were the secondary outcomes.
Source: The American Journal of Cardiology - August 26, 2023 Category: Cardiology Authors: Tulio Caldonazo, Hristo Kirov, Torsten Doenst, Panagiotis Tasoudis, Alexandros Moschovas, Gloria Faerber, Ricardo E. Treml, Michel Pompeu S á, Murat Mukharyamov, Mahmoud Diab Source Type: research

Long-term Incidence of Ischemic Stroke Following Transient Ischemic Attack: A Nationwide Study During 2014-2020
Conclusions: Patients with first-time TIA had an ischemic stroke incidence of 6.1% during the 5-year follow-up period. Following adjustment for relevant comorbidities, this incidence was approximately five-fold higher than what was found for controls in the background population, and 40% lower than for patients with recurrent ischemic stroke.PMID:37622531 | DOI:10.1161/CIRCULATIONAHA.123.065446
Source: Circulation - August 25, 2023 Category: Cardiology Authors: Naja Emborg Vinding Jawad H Butt Marie Dam Lauridsen S øren Lund Kristensen S øren Paaske Johnsen Johanna Kr øll Peter L Graversen Christina Kruuse Christian Torp-Pedersen Lars K øber Emil L Fosb øl Source Type: research

Ischaemic stroke despite antiplatelet therapy: Causes and outcomes
CONCLUSIONS: One-third of ischaemic strokes occurred despite APT and 20% of patients with a history of ischaemic stroke had no antithrombotic therapy when having stroke recurrence. Aetiology of breakthrough strokes despite APT is heterogeneous and these patients are at increased risk of recurrent stroke.PMID:37622482 | DOI:10.1177/23969873231174942
Source: Atherosclerosis - August 25, 2023 Category: Cardiology Authors: Norbert Silimon Boudewijn Drop Leander Cl énin Krassen Nedeltchev Timo Kahles Alexander A Tarnutzer Mira Katan Leo Bonati Stephan Salmen Sylvan Albert Alexander Salerno Emmanuel Carrera Christian Berger Nils Peters Friedrich Medlin Carlo Cereda Manuel Bo Source Type: research

Long-term Incidence of Ischemic Stroke Following Transient Ischemic Attack: A Nationwide Study During 2014-2020
Conclusions: Patients with first-time TIA had an ischemic stroke incidence of 6.1% during the 5-year follow-up period. Following adjustment for relevant comorbidities, this incidence was approximately five-fold higher than what was found for controls in the background population, and 40% lower than for patients with recurrent ischemic stroke.PMID:37622531 | DOI:10.1161/CIRCULATIONAHA.123.065446
Source: Circulation - August 25, 2023 Category: Cardiology Authors: Naja Emborg Vinding Jawad H Butt Marie Dam Lauridsen S øren Lund Kristensen S øren Paaske Johnsen Johanna Kr øll Peter L Graversen Christina Kruuse Christian Torp-Pedersen Lars K øber Emil L Fosb øl Source Type: research

GDF ‐15 at admission predicts cardiovascular death, heart failure, and bleeding outcomes in patients with CAD
ConclusionsIn patients with CAD, admission levels of GDF-15 were associated with an increased 1  year risk of CV death, HF, and bleeding outcomes, but not with thrombotic events. GDF-15 may be a prognostic biomarker for CV death, HF, and bleeding outcomes and could be used to refine the risk assessment of these specific clinical outcomes.Trial Registration:ClinicalTrials.gov Identifier: NCT04044066
Source: ESC Heart Failure - August 25, 2023 Category: Cardiology Authors: Jiali Wang, Tao Zhang, Feng Xu, Wei Gao, Ming Chen, Huadong Zhu, Jun Xu, Xinxin Yin, Jiaojiao Pang, Song Zhang, Mengke Wei, Jiahao Chen, Ying Liu, Xuezhong Yu, Derek P. Chew, Yuguo Chen Tags: Original Article Source Type: research

Cardiovascular Complications in Pregnancy
AbstractPurpose of reviewWe review the epidemiology, risk factors, presentation, pathophysiology, diagnosis, peripartum management, and postpartum follow-up of chronic hypertension, hyperlipidemia, acute myocardial infarction, stroke, heart failure, pulmonary embolism, and atrial fibrillation.Recent findingsWe discuss pathophysiology and evidence-based management for chronic hypertension, hyperlipidemia, acute myocardial infarction, stroke, heart failure, pulmonary embolism, and atrial fibrillation.SummaryIt is essential for providers and patients to understand how cardiovascular diseases cause complications in pregnancy a...
Source: Current Treatment Options in Cardiovascular Medicine - August 25, 2023 Category: Cardiology Source Type: research

Angiotensin Receptor-Neprilysin Inhibitor Effects on Atherosclerotic Cardiovascular Disease Events: A Meta-Analysis of Randomized Controlled Trials
In conclusion, this meta-analysis found no association between ARNI therapy and improved ASCVD events in patients with HF.PMID:37619492 | DOI:10.1016/j.amjcard.2023.07.154
Source: Atherosclerosis - August 24, 2023 Category: Cardiology Authors: Lis Victoria Ravani Douglas Mesadri Gewehr Pedro Calomeni Mateus de Miranda Gauza Jussara Pereira Rhanderson Cardoso Henrique Barbosa Ribeiro Edimar Bocchi Source Type: research

Decreasing national trends in diabetic complications hide regional differences: a prospective population-based study using health care registers in Finland
Conclusions. The decrease in the incidence of first cardiovascular events among patients with diabetes continued from 2010 to 2017 in Finland. However, the declining national incidence rates hide regional differences which should be a target for improvement.PMID:37614115 | DOI:10.1080/14017431.2023.2247190
Source: Scandinavian Cardiovascular Journal - August 24, 2023 Category: Cardiology Authors: Klas Winell Martti Arffman Veikko Salomaa Source Type: research