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Total 12111 results found since Jan 2013.
Mitochondrial dysfunction and oxidative stress contribute to cross-generational toxicity of benzo(a)pyrene in Danio rerio
This study evaluated the role of mitochondria, which are maternally inherited, in the cross-generational toxicity of benzo(a)pyrene (BaP), a model PAH and known mitochondrial toxicant. Mature female zebrafish (F0) were fed diets containing 0, 12.5, 125, or 1250 μg BaP/g at a feed rate of 1% body weight twice/day for 21 days. These females were bred with unexposed males, and the embryos (F1) were collected for subsequent analyses. Maternally-exposed embryos exhibited altered mitochondrial function and metabolic partitioning (i.e. the portion of respiration attributable to different cellular processes), as evidenced by in v...
Source: Aquatic Toxicology - September 18, 2023 Category: Toxicology Authors: Jordan S Kozal Nishad Jayasundara Andrey Massarsky Casey D Lindberg Anthony N Oliveri Ellen M Cooper Edward D Levin Joel N Meyer Richard T Di Giulio Source Type: research
Uncovering associations between gender nonconformity, psychosocial factors, and mental health in adolescents: a birth cohort study
CONCLUSIONS: Persistent gender nonconformity during adolescence is associated with subsequent mental health. Psychosocial factors play a vital mediating role in this association, highlighting the essential need for social intervention and change to reduce stigmatization and ameliorate mental health challenges.PMID:37721216 | DOI:10.1017/S0033291723002623
Source: Psychological Medicine - September 18, 2023 Category: Psychiatry Authors: Zui Narita Jordan DeVylder Syudo Yamasaki Shuntaro Ando Kaori Endo Mitsuhiro Miyashita Satoshi Yamaguchi Satoshi Usami Daniel Stanyon Gemma Knowles Mariko Hiraiwa-Hasegawa Toshiaki A Furukawa Kiyoto Kasai Atsushi Nishida Source Type: research
Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study
CONCLUSION: Pandemic-associated restrictions led to fewer primary care consultations and relative increases in analgesic prescribing, including strong opioids, for RMDs in the UK. Policymakers must consider the impact of these changes in future healthcare resource planning.PMID:37722859 | DOI:10.3399/BJGP.2022.0648
Source: The British Journal of General Practice - September 18, 2023 Category: Primary Care Authors: Victoria K Welsh Kayleigh J Mason James Bailey Ram Bajpai Kelvin P Jordan Christian D Mallen Claire Burton Source Type: research
Performance Validity Testing on the NIH Toolbox Cognition Battery: Base Rates of Failed Embedded Validity Indicators in the Adult Normative Sample
CONCLUSIONS: Multivariable EVIs requiring ≥ 4 failures using liberal cutoffs or ≥ 3 failures using conservative cutoffs had acceptable false-positive rates (i.e., < 10%) using both age-adjusted standard scores and demographically adjusted T-scores. These multivariable EVIs could be applied to large data sets with NIHTB-CB data to screen for potentially invalid test performances.PMID:37718664 | DOI:10.1093/arclin/acad071
Source: Archives of Clinical Neuropsychology - September 18, 2023 Category: Psychiatry & Psychology Authors: Justin E Karr Cristina N Pinheiro Jordan P Harp Source Type: research
Google Ad NFL Kickoff Eyes New Lens For Search
Fashion comes to life in the new Google spot, New Ways to Search: Tunnel Fits, that showcases searches with the Google app through Lens. The focus is on visual and creative with Search Generative Experience (SGE), as Stefon Diggs, DeVonta Smith, Derwin James, Cam Jordan, and Aaron Donald — some of…#google #lens #sge #stefondiggs #devontasmith #derwinjames #camjordan #aarondonald #nfl #nbcfootballnight
Source: Reuters: Health - September 16, 2023 Category: Consumer Health News Source Type: news
Canadian Blood Services traceback investigation of a suspected case of transfusion-transmitted malaria
CONCLUSION: This was a probable transfusion-transmitted malaria (TTM) case from an eligible donor who in retrospect was found to have unrecognized, asymptomatic, semi-immune malaria infection, and who was potentially infectious. Blood donor lack of recall of prior malaria infection does not negate the risk of TTM from those who have lived in malaria-endemic countries.PMID:37715564 | DOI:10.1111/trf.17549
Source: Transfusion - September 16, 2023 Category: Hematology Authors: Bryan Tordon Steven J Drews Francine Flahr Kathleen Bennett Teresa Gaziano Danielle Anderson Susan Nahirniak Hanan Gerges Gregory J Tyrrell Jordan Mah Momar Ndao Mark Bigham Matthew Seftel Source Type: research
Genetic dissection of root architecture in Ethiopian sorghum landraces
This study quantified genetic variation in root system architecture (root number, angle, length and dry mass) within a diversity panel of 1771 Ethiopian sorghum landraces and identified 22 genomic regions associated with the root variations. The root system architecture (RSA) of crop plants influences adaptation to water-limited conditions and determines the capacity of a plant to access soil water and nutrients. Four key root traits (number, angle, length and dry mass) were evaluated in a diversity panel of 1771 Ethiopian sorghum landraces using purpose-built root chambers. Significant genetic variation was observed in al...
Source: TAG. Theoretical and Applied Genetics - September 16, 2023 Category: Genetics & Stem Cells Authors: Temesgen Menamo Andrew K Borrell Emma Mace David R Jordan Yongfu Tao Colleen Hunt Bantte Kassahun Source Type: research
Canadian Blood Services traceback investigation of a suspected case of transfusion-transmitted malaria
CONCLUSION: This was a probable transfusion-transmitted malaria (TTM) case from an eligible donor who in retrospect was found to have unrecognized, asymptomatic, semi-immune malaria infection, and who was potentially infectious. Blood donor lack of recall of prior malaria infection does not negate the risk of TTM from those who have lived in malaria-endemic countries.PMID:37715564 | DOI:10.1111/trf.17549
Source: Transfusion - September 16, 2023 Category: Hematology Authors: Bryan Tordon Steven J Drews Francine Flahr Kathleen Bennett Teresa Gaziano Danielle Anderson Susan Nahirniak Hanan Gerges Gregory J Tyrrell Jordan Mah Momar Ndao Mark Bigham Matthew Seftel Source Type: research
Genetic dissection of root architecture in Ethiopian sorghum landraces
This study quantified genetic variation in root system architecture (root number, angle, length and dry mass) within a diversity panel of 1771 Ethiopian sorghum landraces and identified 22 genomic regions associated with the root variations. The root system architecture (RSA) of crop plants influences adaptation to water-limited conditions and determines the capacity of a plant to access soil water and nutrients. Four key root traits (number, angle, length and dry mass) were evaluated in a diversity panel of 1771 Ethiopian sorghum landraces using purpose-built root chambers. Significant genetic variation was observed in al...
Source: TAG. Theoretical and Applied Genetics - September 16, 2023 Category: Genetics & Stem Cells Authors: Temesgen Menamo Andrew K Borrell Emma Mace David R Jordan Yongfu Tao Colleen Hunt Bantte Kassahun Source Type: research
Human PLCG2 Haploinsufficiency Results in a Novel NK Cell Immunodeficiency
CONCLUSIONS: PLCG2 haploinsufficiency represents a distinct syndrome from previous variants characterized by NK cell immunodeficiency with herpes virus susceptibility, expanding the spectrum of PLCG2-related disease.PMID:37714437 | DOI:10.1016/j.jaci.2023.09.002
Source: Herpes - September 15, 2023 Category: Infectious Diseases Authors: Joshua B Alinger Emily M Mace Justin R Porter Annelise Y Mah-Som Allyssa L Daugherty Stephanie Li Allison A Throm Jeanette T Pingel Nermina Saucier Albert Yao Ivan K Chinn James R Lupski Mohammad Ehlayel Michael Keller Greg R Bowman Megan A Cooper Jordan Source Type: research
Features of Knee and Multi-joint Osteoarthritis by Sex and Race/Ethnicity: A Preliminary Analysis in the Johnston County Health Study
CONCLUSION: Preliminary findings in the diverse JoCoHS cohort suggest more lower extremity predominant MJOA in men compared to women. Women and Black participants had more KOA features and more severe symptoms. Hispanic participants appear to have higher pain and symptoms scores despite having fewer structural changes. Studies in diverse populations are needed to understand the burden of OA.PMID:37714542 | DOI:10.3899/jrheum.2023-0479
Source: J Rheumatol - September 15, 2023 Category: Rheumatology Authors: Sherwin Novin Carolina Alvarez Jordan Renner Yvonne Golightly Amanda Nelson Source Type: research
ASO Visual Abstract: Variations in Travel Patterns Affect Regionalization of Complex Cancer Surgery in California
Ann Surg Oncol. 2023 Sep 15. doi: 10.1245/s10434-023-14285-7. Online ahead of print.NO ABSTRACTPMID:37715110 | DOI:10.1245/s10434-023-14285-7
Source: Ann Oncol - September 15, 2023 Category: Cancer & Oncology Authors: Muhammad Musaab Munir Yutaka Endo Selamawit Woldesenbet Joal Beane None Mary Dillhoff Aslam Ejaz Jordan Cloyd Timothy M Pawlik Source Type: research
Neighborhood park access and park characteristics are associated with weight status in youth
This study investigated park access and park quality in the context of childhood obesity. Participants were 20,638 children ages 6-17y from a large primary care health system. Analyses tested associations of park access and park characteristics with children's weight status, and sociodemographic interactions. Both park access and the quality of nearest park were associated with a lower odds of having obesity. Park quality interacted with age, sex, and income. Findings suggest park access is important for supporting a healthy weight in children. Park quality may be most important among 12-14-year-olds, girls, and higher inc...
Source: Health and Place - September 15, 2023 Category: Environmental Health Authors: Qianxia Jiang Jordan A Carlson Andrew T Kaczynski Robin P Shook Gina M Besenyi Chelsea Steel Mallory Moon Sarah E Hampl Sonja Wilhelm Stanis Source Type: research
