Filtered By:
Source: European Review for Medical and Pharmacological Sciences
This page shows you your search results in order of date. This is page number 7.
Order by Relevance | Date
Total 305 results found since Jan 2013.
Prostaglandin E2 receptor subtypes 1 and 2 play a role in TGF- β1-induced renal fibrosis by regulating endoplasmic reticulum stress.
CONCLUSIONS: EP1 receptor may increase TGF-β1-induced cell damage by increasing the activities of GRP78, TRPC1, and ERK1/2 via ER stress. Meanwhile, the EP2 receptor may reduce TGF-β1-induced cell damage by suppressing GRP78, TRPC1, and ERK1/2 activities, also via ER stress. EP1 inhibition and EP2 stimulation may be a therapeutic option for delaying renal fibrosis.
PMID: 32432758 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - May 22, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
The effect of Casitas b-lineage lymphoma b on regulating T follicular helper in lupus nephritis.
CONCLUSIONS: Cblb showed a negative regulatory effect on Tfh. The deletion of Cblb may be a key factor in progression of renal injury.
PMID: 32373983 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - May 7, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
LncRNA NEAT1 regulates proliferation, apoptosis and invasion of liver cancer.
CONCLUSIONS: LncRNA NEAT1 expression is increased in liver cancer tissues. Down-regulation of LncRNA NEAT1 can inhibit EGFR expression and promote hepatoma cell apoptosis, inhibit cell cycle, thus inhibiting tumor proliferation and invasion.
PMID: 32373951 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - May 7, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
LncRNA UCA1 regulates proliferation, migration and invasion of cervical cancer cells by targeting miR-145.
CONCLUSIONS: LncRNA UCA1 expression is significantly increased in cervical cancer and miR-145 expression is decreased with a negative correlation between them. Lnc-RNA UCA1 regulates cervical cancer cell proliferation, migration, and invasion by targeting miR-145.
PMID: 32329829 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - April 26, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Mechanism of FGF7 gene silencing in regulating viability, apoptosis, invasion of retinoblastoma cell line HXO-Rb44 and angiogenesis.
CONCLUSIONS: FGF7 gene silencing can inhibit the viability and invasion of RB cells and the expression of angiogenesis-related factors and can promote RB apoptosis.
PMID: 32329827 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - April 26, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
MiR-1301 promotes adipogenic and osteogenic differentiation of BMSCs by targeting Satb2.
CONCLUSIONS: Regulation of miR-1301 expression in BMSCs can improve BMSCs proliferation and regulate their adipogenic and osteogenic differentiation by regulating Satb2.
PMID: 32329823 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - April 26, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Low expression of miR-1 promotes osteogenic repair of bone marrow mesenchymal stem cells by targeting TLR1.
CONCLUSIONS: The downregulation of miR-1 promotes BMSCs osteogenic differentiation via targeting TLR1, which promotes osteogenic differentiation and bone healing.
PMID: 32329822 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - April 26, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Hsa_circ_001193 regulates proliferation and apoptosis of nasopharyngeal carcinoma cells through targeting mir-496.
CONCLUSIONS: Hsa_circ_001193 can serve as the miR-496 sponge, which regulates proliferation and apoptosis of NPC cells through up-regulating miR-496. Our findings provide a new therapeutic target for NPC.
PMID: 32271424 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - April 10, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Lnc-RNA BLACAT1 regulates differentiation of bone marrow stromal stem cells by targeting miR-142-5p in osteoarthritis.
CONCLUSIONS: Lnc-RNA BLACAT1 expression was increased in inflammatory BMSCs, and knockdown of BLACAT1 promoted proliferation and osteogenic differentiation of BMSCs targeting miR-142-5p.
PMID: 32271407 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - April 10, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Circular RNA circ_0103552 promotes the invasion and migration of thyroid carcinoma cells by sponging miR-127.
CONCLUSIONS: The present study demonstrated that circ-0103552 acts as a regulator in the invasion and migration of TC by sponging miR-127.
PMID: 32196608 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - March 21, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Relationship between miR-375 regulating Ndrg2/IL-6/STAT3 signaling pathway and diabetic retinopathy in rats.
CONCLUSIONS: MiR-375 inhibitors are able to reduce blood glucose, retinal permeability, and optic ganglion apoptosis in rats with DR, and the mechanism of action may be related to the regulation on the Ndrg2/IL-6/STAT3 signaling pathway.
PMID: 32196570 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - March 21, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Effect of lncRNA AK023948 on rats with postmenopausal osteoporosis via PI3K/AKT signaling pathway.
CONCLUSIONS: LncRNA AK0 can regulate the phosphorylation level of AKT in osteoblasts of rats with estrogen deficiency-related osteoporosis through the PI3K/AKT signaling pathway, thus regulating the proliferation of osteoblasts. It is speculated that lncRNA AK0 may be an important factor in regulating the PI3K/AKT signaling pathway.
PMID: 32196569 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - March 21, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
PKC α and Netrin-1/UNC5B positive feedback control in relation with chemical therapy in bladder cancer.
CONCLUSIONS: PKCα and netrin-1/UNC5B form a positive feedback control loop in relation to the regulation of cisplatin in bladder cancer cells.
PMID: 32141538 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - March 7, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
LncRNA ROR1-AS1 promotes colon cancer cell proliferation by suppressing the expression of DUSP5/CDKN1A.
CONCLUSIONS: ROR1-AS1 is highly expressed either in colon cancer tissues or in cell lines, which is able to enhance cell proliferation, accelerate cell cycle, and inhibit cell apoptosis. The mechanism of ROR1-AS1 to participate in the development of colon cancer may be the downregulation of DUSP5 via combination with EZH2.
PMID: 32096171 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 26, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Dysregulation of microRNA-770-5p influences pancreatic- β-cell function by targeting TP53 regulated inhibitor of apoptosis 1 in gestational diabetes mellitus.
CONCLUSIONS: The data demonstrated that miR-770-5p was a vital regulator in pancreatic β-cell proliferation, apoptosis and insulin secretion by targeting TRIAP1, and dysregulation of miR-770-5p resulted in the development of GDM via APAF1 signaling pathway.
PMID: 32016984 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 6, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
