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Source: European Review for Medical and Pharmacological Sciences
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Total 305 results found since Jan 2013.
The mechanisms of β-catenin on keloid fibroblast cells proliferation and apoptosis.
CONCLUSIONS: Knockdown of β-catenin significantly decreased the proliferation and increased apoptosis of KFB, which could inhibit the formation of pathological scar.
PMID: 29509234 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - March 8, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Paraquat promotes the epithelial-mesenchymal transition in alveolar epithelial cells through regulating the Wnt/ β-catenin signal pathway.
CONCLUSIONS: PQ promotes RLE-6TN epithelial-mesenchymal transition by upregulating the expression of Wnt/β-catenin.
PMID: 29461613 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 22, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
High expression of lnc-CRNDE presents as a biomarker for acute myeloid leukemia and promotes the malignant progression in acute myeloid leukemia cell line U937.
CONCLUSIONS: LncRNA-CRNDE is highly expressed in the bone marrow tissues of AML patients, and the expression level is negatively correlated with the total survival of those clinical patients. Meanwhile, the expression is higher in FAB type M4 and M5 than that in M1, M2 and M3. LncRNA-CRNDE promotes the proliferation and cell cycle of U937 cells, and inhibits cell apoptosis, which is expected to become a molecular marker for predicting and treating AML.
PMID: 29461608 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 22, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
MicroRNA-298 regulates apoptosis of cardiomyocytes after myocardial infarction.
CONCLUSIONS: MiR-298 can improve the myocardial apoptosis through the target gene BAX.
PMID: 29424914 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 11, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
miRNA211 induces apoptosis of cervical cancer SiHa cells via down-regulation of inhibitor of apoptosis proteins.
CONCLUSIONS: MiRNA211 inhibits the growth of SiHa cells via down-regulation of IAPs.
PMID: 29424890 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 11, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Cisplatin induces apoptosis of hepatocellular carcinoma LM3 cells via down-regulation of XIAP.
CONCLUSIONS: Downregulation of XIAP enhanced the proapoptotic effect of cisplatin on LM3 cells, suggesting that XIAP might be used as a potential target in the treatment of liver cancer.
PMID: 29424923 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 11, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Role of long non-coding RNA SNHG1 in occurrence and progression of ovarian carcinoma.
CONCLUSIONS: LncRNA SNHG1 is highly expressed in ovarian carcinoma, which can promote the growth, invasion and metastasis of ovarian carcinoma cells. The down-regulation of SNHG1 can inhibit the proliferation, invasion and metastasis of SKOV-3 cells. Inhibiting the expression of SNHG1 may be a potentially effective means of treating ovarian carcinoma.
PMID: 29424921 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 11, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Silencing of LncRNA TCONS_00088786 reduces renal fibrosis through miR-132.
CONCLUSIONS: Decreased lncRNA TCONS _00088786 inhibits renal interstitial fibrosis by reducing miR-132 and it may be a potential novel molecular target for the treatment of renal interstitial fibrosis.
PMID: 29364484 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - January 26, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Silencing of hsa_circ_0007534 suppresses proliferation and induces apoptosis in colorectal cancer cells.
CONCLUSIONS: Hsa_circ_0007534 plays a crucial role in the initiation and progression of CRC and may be a potential therapeutic target of CRC.
PMID: 29364478 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - January 26, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
MiRNA-155 promotes the invasion of colorectal cancer SW-480 cells through regulating the Wnt/ β-catenin.
CONCLUSIONS: The findings of this study suggest that miR-155 and β-catenin may have a unique potential as a novel biomarker candidate for diagnosis and treatment of tumor metastasis.
PMID: 29364476 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - January 26, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
The regulatory role of SLP-2 and mechanism on CCBE1 gene expression in rectal carcinoma and adjacent lymphatic tube tissues.
CONCLUSIONS: SLP-2 is up-regulated in RC lymphatic tissues, and is positively correlated with the level of CCBE1, which provides the academic the basis for the development of medicine targeting SLP-2 in the anti-rectal carcinoma therapy.
PMID: 29364474 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - January 26, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Effect of β-arrestin on damage of human umbilical vein endothelial cell induced by angiotensin II.
CONCLUSIONS: ARRB2 could protect the damage of HUVECs induced by Ang II and the mechanism was associated with upregulation of the expression of apoptosis and anti-apoptosis protein of Bcl-2.
PMID: 29272019 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - December 24, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Hypoxia promotes invasion of retinoblastoma cells in vitro by upregulating HIF-1 α/MMP9 signaling pathway.
CONCLUSIONS: Hypoxia promotes retinoblastoma cell line HXO-RB44 invasion by activating HIF-1α/MMP9 signaling pathway.
PMID: 29243776 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - December 17, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
CD44V6 regulates gastric carcinoma occurrence and development through up-regulating VEGF expression.
CONCLUSIONS: CD44V6 participates in GC occurrence and development by up-regulating VEGF expression. Targeting CD44V6 regulates GC progression through inhibiting VEGF expression, promoting cell apoptosis, and restraining cell proliferation.
PMID: 29228423 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - December 13, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
MiR-96 expression in prostate cancer and its effect on the target gene regulation.
CONCLUSIONS: As target genes of miR-96, FOXO1 and FOXO3a confer protection against prostatic cancer, while the inhibition of FOXO1 and FOXO3a enhances cancer proliferation.
PMID: 29131261 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - November 14, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
