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Source: Oncology Reports

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Total 403 results found since Jan 2013.

Retracted Synergistic effects of eukaryotic co ‑expression plasmid‑based STAT3‑specific siRNA and LKB1 on ovarian cancer < em > in  vitro < /em > and < em > in  vivo < /em >
Oncol Rep. 2021 Sep;46(3):198. doi: 10.3892/or.2021.8149. Epub 2021 Jul 23.ABSTRACTFollowing the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the western blotting data shown in Figs. 1C and 6D bore unexpected similarities to data appearing in different form in other articles by different authors. Owing to the fact that some of the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to Oncology Reports, the Editor has decided that this paper should be retracted from ...
Source: Oncology Reports - July 23, 2021 Category: Cancer & Oncology Authors: Yuan Pan Liqun Zhang Xinyue Zhang Ruizhi Liu Source Type: research

ND ‑09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR‑ABL signaling
Oncol Rep. 2021 Jul;46(1):136. doi: 10.3892/or.2021.8087. Epub 2021 May 26.ABSTRACTChronic myeloid leukemia (CML) accounts for approximately 15% of new adult leukemia cases. The fusion gene BCR‑ABL is an important biological basis and target for CML. In the present study, a novel compound, ND‑09, was developed and its inhibitory effect and mechanism of action on CML growth were evaluated using RT‑PCR and western blot analysis. The results showed that ND‑09 demonstrated a high level of inhibitory action toward CML cells overexpressing BCR‑ABL and induced K562 cell apoptosis through the mitochondrial pathway. Notab...
Source: Oncology Reports - May 26, 2021 Category: Cancer & Oncology Authors: Yan-Hong Liu Man Zhu Pan-Pan Lei Xiao-Yan Pan Wei-Na Ma Source Type: research

Sodium bicarbonate transporter NBCe1 regulates proliferation and viability of human prostate cancer cells LNCaP and PC3
In conclusion, our study demonstrates that NBCe1 regulates acid extrusion in prostate cancer cells and inhibiting or abolishing this transporter decreases cancer cell proliferation.PMID:34013380 | DOI:10.3892/or.2021.8080
Source: Oncology Reports - May 20, 2021 Category: Cancer & Oncology Authors: Jun Ming Li Soojung Lee Reda Zafar Eunjung Shin Inyeong Choi Source Type: research

Corrigendum MicroRNA ‑122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma
Oncol Rep. 2021 Jul;46(1):122. doi: 10.3892/or.2021.8073. Epub 2021 May 13.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that Figs. 6C and 7A apparently contained overlapping panels, suggesting that these data for purportedly different experiments had been derived from the same original source. The wound‑healing result for the anti‑miR‑122+siRNA PKM2 experiment in the lower panel of Fig. 6C and the transwell invasion result for the anti‑miR‑122+siRNA PKM2 experiment in Fig. 7A were erroneously selected. Accordingly, the authors repeated these assays an...
Source: Oncology Reports - May 13, 2021 Category: Cancer & Oncology Authors: Qiuran Xu Meiqi Zhang Jianfeng Tu Linxiao Pang Wenwei Cai Xin Liu Source Type: research