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Source: Cancer Science
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Total 106 results found since Jan 2013.
Prostate cancer stem‐like cells/cancer‐initiating cells have an autocrine system of hepatocyte growth factor
Abstract
Prostate cancer cells include a small population of cancer stem‐like cells (CSCs)/cancer‐initiating cells (CICs) that have roles in initiation and progression of the cancer. Recently, we isolated prostate CSCs/CICs as aldehyde dehydrogenase 1‐highh (ALDH1high) cells using the ALDEFLUOR assay; however, the molecular mechanisms of prostate CSCs/CICs are still elusive. Prostate CSCs/CICs were isolated as ALDH1high cells using the ALDEFLUOR assay, and the gene expression profiles were analyzed using a cDNA microarray and RT‐PCR. We found that prostate CSCs/CICs expressed higher levels of growth factors includi...
Source: Cancer Science - January 1, 2013 Category: Cancer & Oncology Authors: Sachiyo Nishida, Yoshihiko Hirohashi, Toshihiko Torigoe, Ryuta Inoue, Hiroshi Kitamura, Toshiaki Tanaka, Akari Takahashi, Hiroko Asanuma, Naoya Masumori, Taiji Tsukamoto, Noriyuki Sato Tags: Original Article Source Type: research
