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PARN Knockdown in Cell Lines Results in Differential and Cell-Specific Alterations in the Expression of Cancer-Associated mRNAs
CONCLUSION: The results of this study reveal that PARN deficiency leads to an altered stability of cancer-associated mRNA, distinctly, in cells of different lineages. Despite previous reports suggesting a potential therapeutic role of PARN in cancer, our results suggest that PARN may not be an important biomarker, particularly in lung cancer.PMID:35092390 | DOI:10.31557/APJCP.2022.23.1.207
Source: Asian Pacific Journal of Cancer Prevention - January 29, 2022 Category: Cancer & Oncology Authors: Nishith Babu Dechamma Pandyanda Nanjappa Sandra Nazareth Srividya Arjuna Anirban Chakraborty Source Type: research
