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Cancer: Lymphoma
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Total 468 results found since Jan 2013.
CBL inhibits proliferation and invasion of breast cancer cells by ubiquitylation-mediated degradation of NCK2
CONCLUSION: CBL can inhibit the proliferation, migration and invasion of breast cancer cells through ubiquitination-mediated degradation of NCK2.PMID:36504051 | PMC:PMC9742774 | DOI:10.12122/j.issn.1673-4254.2022.11.02
Source: Journal of Southern Medical University - December 12, 2022 Category: Universities & Medical Training Authors: X Song B Xiao J Lu W Zhang J Li X Zhu Z Sun L Li Source Type: research
Current advancements in self-assembling nanocarriers-based siRNA delivery for cancer therapy
Colloids Surf B Biointerfaces. 2022 Nov 2;221:113002. doi: 10.1016/j.colsurfb.2022.113002. Online ahead of print.ABSTRACTDifferent therapeutic practices for treating cancers have significantly evolved to compensate and/or overcome the failures in conventional methodologies. The demonstrated potentiality in completely inhibiting the tumors and in preventing cancer relapse has made nucleic acids therapy (NAT)/gene therapy as an attractive practice. This has been made possible because NAT-based cancer treatments are highly focused on the fundamental mechanisms - i.e., silencing the expression of oncogenic genes responsible fo...
Source: Colloids and Surfaces - November 12, 2022 Category: Biotechnology Authors: Ganeshlenin Kandasamy Dipak Maity Source Type: research
CC1007, a small molecular compound, suppresses multiple myeloma via upregulation of Nur77
CONCLUSIONS: Since CC1007 demonstrates remarkable anti-MM effect on MM cells, it may be a promising drug for the treatment of MM.PMID:36283176 | DOI:10.1016/j.bioorg.2022.106217
Source: Bioorganic Chemistry - October 25, 2022 Category: Chemistry Authors: Shicong Zhu Cheng Xing Guangsen Zhang Hongling Peng Zhihua Wang Source Type: research
Cornin protects against cerebral ischemia/reperfusion injury by preventing autophagy via the PI3K/Akt/mTOR pathway
CONCLUSIONS: These results indicate that cornin improved neurological recovery after cerebral ischemia injury by preventing astrocytes autophagy induced by CI/R via the PI3K/Akt/mTOR signaling pathway.PMID:36280856 | DOI:10.1186/s40360-022-00620-3
Source: BMC Pharmacology and Toxicology - October 25, 2022 Category: Drugs & Pharmacology Authors: Tianchi Lan Yangyang Xu Shucui Li Ning Li Shuping Zhang Haibo Zhu Source Type: research
Blockade of interleukin-6 receptor attenuates apoptosis and modulates the inflammatory response in Mycoplasma pneumoniae infected A549 cells
CONCLUSION: Silencing the IL-6 gene can reduce the MP-induced inflammatory response and oxidative stress of A549 cells, enhance cell viability and inhibit apoptosis. Meanwhile, it was also found that STAT3 expression was inhibited after silencing IL-6 gene expression. Therefore, it is speculated that IL-6 may play a role by regulating STAT3, but its exact molecular biological mechanism still needs to be further explored.PMID:36247299 | PMC:PMC9556488
Source: American Journal of Translational Research - October 17, 2022 Category: Research Authors: Wei Fang Jingyu Huang Jun Wang Tengyi Huang Dajia Lin Jun Yin Source Type: research
