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Cancer: Nasopharyngeal Cancer

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Total 152 results found since Jan 2013.

Abstracts of Presentations at the Association of Clinical Scientists 143 < sup > rd < /sup > Meeting Louisville, KY May 11-14,2022
Conclusion: These assays are suitable for routine diagnostic. The UltraFast NextGenPCR is the fastest with average time (30mins), followed by Agilent (2 hrs) and MassArray (6hrs). Upon completion of this activity, participants should be able to examine, measure and compare results from different assays for SARS detection, evaluate and diagnose accurately, as well as being able to plan, organize and recommend a diagnostic procedure for diagnostic laboratory. Key words: SARS-CoV-2, RNA extraction, RT-PCR, limit of detection, quantification cycle, COVID-19, in vitro diagnostic tests, Agilent, Massarray, Ultrafast. [20] From t...
Source: Annals of Clinical and Laboratory Science - July 1, 2022 Category: Laboratory Medicine Source Type: research

Cancers, Vol. 14, Pages 3125: The CBP/ & beta;-Catenin Antagonist, ICG-001, Inhibits Tumor Metastasis via Blocking of the miR-134/ITGB1 Axis-Mediated Cell Adhesion in Nasopharyngeal Carcinoma
Cancers, Vol. 14, Pages 3125: The CBP/&beta;-Catenin Antagonist, ICG-001, Inhibits Tumor Metastasis via Blocking of the miR-134/ITGB1 Axis-Mediated Cell Adhesion in Nasopharyngeal Carcinoma Cancers doi: 10.3390/cancers14133125 Authors: Luo Chen Yiu Chun Chiang Lai Sheung Chan Wai Yin Chau Maria Li Lung Michael Kahn Kwok Wai Lo Nai Ki Mak Hong Lok Lung Nasopharyngeal carcinoma (NPC) is an Epstein&amp;ndash;Barr virus (EBV)-associated malignancy ranking as the 23rd most common cancer globally, while its incidence rate ranked the 9th in southeast Asia. Tumor metastasis is the dominant cause for...
Source: Cancers - June 25, 2022 Category: Cancer & Oncology Authors: Luo Chen Yiu Chun Chiang Lai Sheung Chan Wai Yin Chau Maria Li Lung Michael Kahn Kwok Wai Lo Nai Ki Mak Hong Lok Lung Tags: Article Source Type: research

miR-3942-3p Increases the radiosensitivity of nasopharyngeal carcinoma through negatively regulating BARD1
Acta Biochim Pol. 2022 May 25. doi: 10.18388/abp.2020_5791. Online ahead of print.ABSTRACTNasopharyngeal carcinoma (NPC) has high incidence in China and East and Southeast Asia. The study was performed to investigate the effect of microRNA3942-3p (miR-3942-3p) on the radiosensitivity of NPC. Compared with non-cancer tissue, NPC had significantly lower miR-3942-3p expression. X-irradiation (IR) reduced the expression of miR-3942-3p in a dose-dependent way in NPC cells. Down-regulation of miR-3942-3p using miR-3942-3p inhibitor resulted in significantly increased cell viability, decreased apoptosis of CNE1 cells. Bax decreas...
Source: Acta Biochim Pol - May 26, 2022 Category: Biochemistry Authors: Luxing Peng Jiaxin Chen Heming Lu Jinjian Cheng Qiang Pang Youjun Wu Xu Liu Source Type: research

GALNT14 promotes cancer stem cell-like characteristics and metastasis of nasopharyngeal carcinoma cells through upregulating SOX4
ConclusionGALNT14 promoted the cancer stem cell-like characteristics and metastasis of nasopharyngeal carcinoma cells through upregulating SOX4, providing a potential therapeutic target for nasopharyngeal carcinoma treatment.
Source: Molecular and Cellular Toxicology - November 17, 2021 Category: Cytology Source Type: research

Insulin receptor substrate-1 and dishevelled 2 are negatively regulated by microRNA-144 and inhibit nasopharyngeal carcinoma cell malignancy
Exp Ther Med. 2021 Nov;22(5):1303. doi: 10.3892/etm.2021.10738. Epub 2021 Sep 16.ABSTRACTInsulin receptor substrate-1 (IRS-1) is reported to play a critical role in the development, progression, invasion and metastasis of several types of tumors and is abnormally expressed in nasopharyngeal carcinoma (NPC). Although IRS-1 is predicted to be targeted by microRNA (miR)-144, the biological roles and potential mechanisms of miR-144 in NPC remain unclear. In the present study, the expression levels of miR-144 and IRS-1 in several NPC cell lines were first examined, and found that they were negatively correlated. Following the i...
Source: Experimental and Therapeutic Medicine - October 11, 2021 Category: General Medicine Authors: Xuemei An Yunlan Jiang Defeng Chen Jianjun Chen Source Type: research

Influences of S100A8 and S100A9 on Proliferation of Nasopharyngeal Carcinoma Cells through PI3K/Akt Signaling Pathway
CONCLUSION: SiRNA S100A8 and S100A9 could inhibit the proliferation of nasopharyngeal carcinoma cells, and the underlying mechanism may be related to the inhibition of PI3K/Akt signaling pathway.PMID:34604387 | PMC:PMC8486551 | DOI:10.1155/2021/9917365
Source: Biomed Res - October 4, 2021 Category: Research Authors: Liting Wen Yu Ding Xiaodong Chen Keyong Tian Danfeng Li Kun Liang Bo Yue Source Type: research