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Therapy: Statin Therapy
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Total 12097 results found since Jan 2013.
Novel treatment from a botanical formulation Si-Miao-Yong-an decoction inhibits vasa vasorum angiogenesis and stabilizes atherosclerosis plaques via the Wnt1/ β-catenin signalling pathway
CONCLUSIONS: SMYA has a protective effect against AS, which may be related to its anti-VV angiogenesis in plaques, suggesting that SMYA has the potential as a novel botanical formulation in the treatment of AS.PMID:37651108 | DOI:10.1080/13880209.2023.2249061
Source: Atherosclerosis - August 31, 2023 Category: Cardiology Authors: Zhongwen Qi Zhipeng Yan Ke Zhu Yueyao Wang Yajie Fan Tingting Li Junping Zhang Source Type: research
Evaluation of the efficacy and safety of bempedoic acid in women and men: Pooled analyses from phase 3 trials
CONCLUSIONS: In this pooled analysis, women experienced significant improvements in levels of LDL-C and other lipid parameters with bempedoic acid.PMID:37648637 | DOI:10.1016/j.atherosclerosis.2023.117192
Source: Atherosclerosis - August 30, 2023 Category: Cardiology Authors: Anne C Goldberg Maciej Banach Alberico L Catapano P Barton Duell Lawrence A Leiter Jeffrey C Hanselman Lei Lei G B John Mancini Source Type: research
Statins as a Potential Treatment for Non-Alcoholic Fatty Liver Disease: Target Deconvolution using Protein-protein Interaction Network Analysis
CONCLUSIONS: Simvastatin has the most impact on NAFLD-related genes versus other statins.PMID:37644746 | DOI:10.2174/0929867331666230829164832
Source: Atherosclerosis - August 30, 2023 Category: Cardiology Authors: Ali Mahmoudi Alexandra E Butler Alexander N Orekhov Tannaz Jamialahmadi Amirhossein Sahebkar Source Type: research
Statins, allies against antibiotic resistance?
Curr Med Chem. 2023 Aug 29. doi: 10.2174/0929867331666230829141301. Online ahead of print.ABSTRACTDue to the ever-increasing rate of antibacterial resistance, the search for effective antibacterial agents has become imperative. Researchers have investigated the potential antimicrobial properties of various classes of nonantibiotic drugs. Statins are a group of antihyperlipidemic drugs with several cholesterol-independent effects, including anti-inflammatory, immune-modulating, antioxidant, and antibacterial effects. In vitro and in vivo studies have demonstrated the antibacterial properties of statins against various gram-...
Source: Current Medicinal Chemistry - August 30, 2023 Category: Chemistry Authors: Mohammad Abavisani Melika Hoseinzadeh Reza Khayami Mansoor Kodori Saman Soleimanpour Amirhossein Sahebkar Source Type: research
Statins as a Potential Treatment for Non-Alcoholic Fatty Liver Disease: Target Deconvolution using Protein-protein Interaction Network Analysis
CONCLUSIONS: Simvastatin has the most impact on NAFLD-related genes versus other statins.PMID:37644746 | DOI:10.2174/0929867331666230829164832
Source: Current Medicinal Chemistry - August 30, 2023 Category: Chemistry Authors: Ali Mahmoudi Alexandra E Butler Alexander N Orekhov Tannaz Jamialahmadi Amirhossein Sahebkar Source Type: research
Statins, allies against antibiotic resistance?
Curr Med Chem. 2023 Aug 29. doi: 10.2174/0929867331666230829141301. Online ahead of print.ABSTRACTDue to the ever-increasing rate of antibacterial resistance, the search for effective antibacterial agents has become imperative. Researchers have investigated the potential antimicrobial properties of various classes of nonantibiotic drugs. Statins are a group of antihyperlipidemic drugs with several cholesterol-independent effects, including anti-inflammatory, immune-modulating, antioxidant, and antibacterial effects. In vitro and in vivo studies have demonstrated the antibacterial properties of statins against various gram-...
Source: Current Medicinal Chemistry - August 30, 2023 Category: Chemistry Authors: Mohammad Abavisani Melika Hoseinzadeh Reza Khayami Mansoor Kodori Saman Soleimanpour Amirhossein Sahebkar Source Type: research
Neutrophils for Revascularization Require Activation of CCR6 and CCL20 by TNF α
CONCLUSIONS: We demonstrate that site-specific activation of the CCL20-CCR6 axis via TNFα recruits proangiogenic VEGFA-expressing neutrophils to sites of ischemic injury for initiation of muscle tissue revascularization. The findings provide an attractive option for tissue revascularization, particularly under diabetic conditions.PMID:37641931 | DOI:10.1161/CIRCRESAHA.123.323071
Source: Circulation Research - August 29, 2023 Category: Cardiology Authors: Holger L örchner Laia Ca ñes Esteve Maria Elisa G óes Roxanne Harzenetter Nathalie Brachmann Praveen Gajawada Stefan G ünther Nicolas Doll Jochen P öling Thomas Braun Source Type: research
Recommendations for statin management in primary prevention: disparities among international risk scores
CONCLUSION: Risk algorithms differ substantially in their estimation of risk, recommendations for statin treatment, and use of ancillary testing, even in identical patients. These results highlight the limitations of currently used risk-based approaches for addressing lipid-specific risk in primary prevention.PMID:37638490 | DOI:10.1093/eurheartj/ehad539
Source: Atherosclerosis - August 28, 2023 Category: Cardiology Authors: G B John Mancini Arnold Ryomoto Eunice Yeoh Liam R Brunham Robert A Hegele Source Type: research
Rhabdomyolysis-induced acute kidney injury after administration of a red yeast rice supplement: A case report
CONCLUSION: We speculate that statins, the main lipid-lowering component of RYR, or a combination of statins and abiraterone, will increase the risk of rhabdomyolysis.PMID:37637685 | PMC:PMC10450378 | DOI:10.12998/wjcc.v11.i23.5547
Source: Clinical Prostate Cancer - August 28, 2023 Category: Cancer & Oncology Authors: Ya-Han Wang Si-Shuo Zhang Hai-Tao Li Hong-Wei Zhi Hong-Yun Wu Source Type: research
Silent Myocardial Infarction: A Case Report
We present a case of a 59-year-old overweight woman with prediabetes, primary hypertension, and hypercholesterolemia who presented for herpes zoster (HZ) follow-up; she reported having skipped heartbeats and heart rate fluctuations during the review of systems. On further workup, ECG revealed low voltage QRS complexes, flat QRS complexes, flat T waves, and pathological Q waves, suggesting the diagnosis of SMI. Based on the identified risk factors, including high BMI, prediabetes, primary hypertension, hypercholesterolemia, HZ, and newly diagnosed SMI, the patient was advised to continue with lisinopril 20 mg daily, prescri...
Source: Herpes - August 28, 2023 Category: Infectious Diseases Authors: Maria V Kolesova Suzanne Minor Source Type: research
Rhabdomyolysis-induced acute kidney injury after administration of a red yeast rice supplement: A case report
CONCLUSION: We speculate that statins, the main lipid-lowering component of RYR, or a combination of statins and abiraterone, will increase the risk of rhabdomyolysis.PMID:37637685 | PMC:PMC10450378 | DOI:10.12998/wjcc.v11.i23.5547
Source: Clinical Prostate Cancer - August 28, 2023 Category: Cancer & Oncology Authors: Ya-Han Wang Si-Shuo Zhang Hai-Tao Li Hong-Wei Zhi Hong-Yun Wu Source Type: research
