Filtered By:
Therapy: Statin Therapy
This page shows you your search results in order of date. This is page number 16.
Order by Relevance | Date
Total 12097 results found since Jan 2013.
Clinical Approach in the Management of Paediatric Patients with Familial Hypercholesterolemia: A National Survey Conducted by the LIPIGEN Paediatric Group
Nutrients. 2023 Aug 5;15(15):3468. doi: 10.3390/nu15153468.ABSTRACTDetection and treatment of patients with familial hypercholesterolemia (FH) starting from childhood is fundamental to reduce morbidity and mortality. The activity of National realities such as the LIPIGEN (LIpid transPort disorders Italian GEnetic Network) Paediatric Group, founded in 2018, is a milestone in this context. The aim of this exploratory survey, conducted in October 2021 among Italian lipid clinics included in the LIPIGEN Paediatric Group, was to investigate the current clinical approach in the management and treatment of paediatric patients wit...
Source: Atherosclerosis - August 12, 2023 Category: Cardiology Authors: Cristina Pederiva Marta Gazzotti Marcello Arca Maurizio Averna Giuseppe Banderali Giacomo Biasucci Marta Brambilla Paola Sabrina Buonuomo Paolo Calabr ò Francesco Cipollone Nadia Citroni Sergio D'Addato Maria Del Ben Simonetta Genovesi Ornella Guardamagn Source Type: research
Xinmaikang-mediated mitophagy attenuates atherosclerosis via the PINK1/Parkin signaling pathway
CONCLUSION: The study shows that XMK is effective against AS by mediating macrophage mitophagy via the PINK1/Parkin signaling pathway. For the treatment of AS and drug discovery, it provides an experimental basis and target.PMID:37572567 | DOI:10.1016/j.phymed.2023.154955
Source: Atherosclerosis - August 12, 2023 Category: Cardiology Authors: Yanhong Cao Xin Chen Fuqiang Pan Mingyang Wang Haowen Zhuang Jiangna Chen Lu Lu Lingjun Wang Ting Wang Source Type: research
Clinical Approach in the Management of Paediatric Patients with Familial Hypercholesterolemia: A National Survey Conducted by the LIPIGEN Paediatric Group
Nutrients. 2023 Aug 5;15(15):3468. doi: 10.3390/nu15153468.ABSTRACTDetection and treatment of patients with familial hypercholesterolemia (FH) starting from childhood is fundamental to reduce morbidity and mortality. The activity of National realities such as the LIPIGEN (LIpid transPort disorders Italian GEnetic Network) Paediatric Group, founded in 2018, is a milestone in this context. The aim of this exploratory survey, conducted in October 2021 among Italian lipid clinics included in the LIPIGEN Paediatric Group, was to investigate the current clinical approach in the management and treatment of paediatric patients wit...
Source: Atherosclerosis - August 12, 2023 Category: Cardiology Authors: Cristina Pederiva Marta Gazzotti Marcello Arca Maurizio Averna Giuseppe Banderali Giacomo Biasucci Marta Brambilla Paola Sabrina Buonuomo Paolo Calabr ò Francesco Cipollone Nadia Citroni Sergio D'Addato Maria Del Ben Simonetta Genovesi Ornella Guardamagn Source Type: research
Acute statin withdrawal does not interfere with the improvements of a session of exercise in postprandial metabolism
CONCLUSIONS: In dyslipidemic individuals, statins reduce blood triglyceride concentrations after a meal, but without limiting fat oxidation. Statins do not interfere with the exercise lowering of postprandial insulin that likely promotes fat oxidation. Lastly statins do not restrict the rates of plasma incorporation or oxidation of the ingested glucose.CLINICALTRIALS.GOV IDENTIFIER: NCT04477590.PMID:37565392 | DOI:10.1210/clinem/dgad477
Source: The Journal of Clinical Endocrinology and Metabolism - August 11, 2023 Category: Endocrinology Authors: Laura Alvarez-Jimenez Felix Morales-Palomo Alfonso Moreno-Caba ñas Juan F Ortega Diego Mora-Gonzalez Ricardo Mora-Rodriguez Source Type: research
Pharmacological interventions for asymptomatic carotid stenosis
CONCLUSIONS: Although there is no high-certainty evidence to support pharmacological intervention, this does not mean that pharmacological treatments are ineffective in preventing ischaemic cerebral events, morbidity, and mortality. High-quality RCTs are needed to better inform the best medical treatment that may reduce the burden of carotid stenosis. In the interim, clinicians will have to use other sources of information.PMID:37565307 | PMC:PMC10401652 | DOI:10.1002/14651858.CD013573.pub2
Source: Atherosclerosis - August 11, 2023 Category: Cardiology Authors: Caroline Nb Clezar Carolina Dq Flumignan Nicolle Cassola Luis Cu Nakano Virginia Fm Trevisani Ronald Lg Flumignan Source Type: research
Acute statin withdrawal does not interfere with the improvements of a session of exercise in postprandial metabolism
CONCLUSIONS: In dyslipidemic individuals, statins reduce blood triglyceride concentrations after a meal, but without limiting fat oxidation. Statins do not interfere with the exercise lowering of postprandial insulin that likely promotes fat oxidation. Lastly statins do not restrict the rates of plasma incorporation or oxidation of the ingested glucose.CLINICALTRIALS.GOV IDENTIFIER: NCT04477590.PMID:37565392 | DOI:10.1210/clinem/dgad477
Source: The Journal of Clinical Endocrinology and Metabolism - August 11, 2023 Category: Endocrinology Authors: Laura Alvarez-Jimenez Felix Morales-Palomo Alfonso Moreno-Caba ñas Juan F Ortega Diego Mora-Gonzalez Ricardo Mora-Rodriguez Source Type: research
Pharmacological interventions for asymptomatic carotid stenosis
CONCLUSIONS: Although there is no high-certainty evidence to support pharmacological intervention, this does not mean that pharmacological treatments are ineffective in preventing ischaemic cerebral events, morbidity, and mortality. High-quality RCTs are needed to better inform the best medical treatment that may reduce the burden of carotid stenosis. In the interim, clinicians will have to use other sources of information.PMID:37565307 | PMC:PMC10401652 | DOI:10.1002/14651858.CD013573.pub2
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Caroline Nb Clezar Carolina Dq Flumignan Nicolle Cassola Luis Cu Nakano Virginia Fm Trevisani Ronald Lg Flumignan Source Type: research
Novel pharmacological approaches in abdominal aortic aneurysm
Clin Sci (Lond). 2023 Aug 14;137(15):1167-1194. doi: 10.1042/CS20220795.ABSTRACTAbdominal aortic aneurysm (AAA) is a severe vascular disease and a major public health issue with an unmet medical need for therapy. This disease is featured by a progressive dilation of the abdominal aorta, boosted by atherosclerosis, ageing, and smoking as major risk factors. Aneurysm growth increases the risk of aortic rupture, a life-threatening emergency with high mortality rates. Despite the increasing progress in our knowledge about the etiopathology of AAA, an effective pharmacological treatment against this disorder remains elusive and...
Source: Atherosclerosis - August 10, 2023 Category: Cardiology Authors: L ídia Puertas-Umbert Rafael Almendra-Pegueros Francesc Jim énez-Altayó Marc Sirvent Mar ía Galán Jos é Martínez-González Cristina Rodr íguez Source Type: research
Effects of statins on the incidence and outcomes of acute kidney injury in critically ill patients: a systematic review and meta-analysis
CONCLUSIONS: Our analysis showed a significant association between statin therapy and overall mortality of critically ill surgical patients diagnosed with AKI, while at the same time the use of statins did not affect the length of their stay in ICU.PMID:37560738 | PMC:PMC10408035 | DOI:10.5114/aoms/159992
Source: Archives of Medical Science - August 10, 2023 Category: Biomedical Science Authors: Amir Vahedian-Azimi Farshad Heidari Beni Zlatko Fras Maciej Banach Seyede Momeneh Mohammadi Tannaz Jamialahmadi Amirhossein Sahebkar Source Type: research
Bioinformatic platforms for clinical stratification of natural history of atherosclerotic cardiovascular diseases
Eur Heart J Cardiovasc Pharmacother. 2023 Aug 10:pvad059. doi: 10.1093/ehjcvp/pvad059. Online ahead of print.ABSTRACTAlthough bioinformatic methods gained a lot of attention in the latest years, their use in real-world studies for primary and secondary prevention of atherosclerotic cardiovascular diseases (ASCVD) is still lacking. Bioinformatic resources have been applied to thousands of individuals from the Framingham Heart Study as well as health care-associated biobanks such as the UK Biobank, the Million Veteran Program, and the CARDIoGRAMplusC4D Consortium and randomized controlled trials (i.e. ODYSSEY, FOURIER, ASPRE...
Source: Atherosclerosis - August 10, 2023 Category: Cardiology Authors: Giuditta Benincasa Rosa Suades Teresa Padr ò Lina Badimon Claudio Napoli Source Type: research
