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Condition: Pain
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Total 150988 results found since Jan 2013.
Bilateral orthodontic extractions using physics versus conventional forceps among Indian patients
Bioinformation. 2023 Jan 31;19(1):143-148. doi: 10.6026/97320630019143. eCollection 2023.ABSTRACTIt is of interest to assess whether or not physics forceps are superior to traditional forceps for the extraction of premolar teeth in orthodontic procedures. Tooth and buccal bone fractures, as well as extraction time, lacerated gingiva, postoperative discomfort, and infection, were all measured in this research of both types of forceps extraction. Twenty individuals who need orthodontic extraction on both jaws were enrolled in the research. One arch's premolars were removed in two appointments, the first using Physics forceps...
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Vidhi Sangra H R Hemanth Kumar Arundhati Singh Sandeep Singh Godana Akhilasiri Vivek Agarwal Source Type: research
Inhibition of C5aR1 as a promising approach to treat taxane-induced neuropathy
In conclusion, C5aR1 inhibition is proposed as a therapeutic option with the potential to exert long-term protective effect on PIPN-associated neuropathic pain and inflammation.PMID:37722320 | DOI:10.1016/j.cyto.2023.156370
Source: Cytokine - September 18, 2023 Category: Molecular Biology Authors: C Cristiano C Giorgio P Cocchiaro S Boccella M C Cesta V Castelli F M Liguori M R Cuozzo L Brandolini R Russo M Allegretti Source Type: research
Association of pain neurophysiology knowledge and application amongst UK chiropractic students: A cross-sectional study
CONCLUSION: Chiropractic placement students in the United Kingdom appear to have a lower level of pain knowledge than other health care professionals and education institutions may wish to consider how to best address this within their curricula.PMID:37721388 | DOI:10.7899/JCE-22-27
Source: The Journal of Chiropractic Education - September 18, 2023 Category: Complementary Medicine Authors: Kajsa Nordbo Philip Dewhurst Source Type: research
The Use of Opioids in the Management of Chronic Pain
Ann Intern Med. 2023 Sep;176(9):eL230225. doi: 10.7326/L23-0225.NO ABSTRACTPMID:37722120 | DOI:10.7326/L23-0225
Source: Annals of Internal Medicine - September 18, 2023 Category: Internal Medicine Authors: James L Sall Friedhelm Sandbrink Jennifer L Murphy Christopher Spevak Ellen Edens Source Type: research
The Value of < sup > 18 < /sup > F-FDG PET/MRI in Detecting Lumbar Radiculopathy for Selective Percutaneous Endoscopic Discectomy: a Case Report
Nucl Med Mol Imaging. 2023 Oct;57(5):247-250. doi: 10.1007/s13139-023-00797-3. Epub 2023 Mar 29.ABSTRACTMagnetic resonance imaging (MRI) is the most popular imaging modality for investigating intervertebral disc herniation. However, it has a high chance for identifying incidental findings that are morphologically or structurally abnormal but not responsible for patients' symptoms. Although a previous study suggested that 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) may help identify neuroinflammation in lumbar radiculopathy, there is currently no direct evidence obtaine...
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Chih-Ying Su Guo-Shu Huang Wei-Chou Chang Chih-Chien Wang Chun-Wen Chen Yi-Chih Hsu Source Type: research
Inflammatory cytokines in rheumatoid arthritis: Diagnostic Challenges, Pathogenic Mechanisms and their role in depression and management
Curr Top Med Chem. 2023 Sep 15. doi: 10.2174/1568026623666230915095151. Online ahead of print.ABSTRACTDepression being a common comorbidity of rheumatoid arthritis (RA) is found to be responsible for the reduction in the lifespan of the sufferer along with the compromised quality of life. The study quoted below highlights the pathogenic pathways, the frequency of RA along with its impact on patients, thus, raising awareness about the concerned topic. It is found that the chances and frequency of developing depression are 2-3 times higher in patients with RA in comparison to the general population. For such studies, self-re...
Source: Current Topics in Medicinal Chemistry - September 18, 2023 Category: Chemistry Authors: Ayushi Sharma Anjana Goel Source Type: research
Do educational interventions improve prescribing skills of medical students compared to no additional learning? A systematic review
Med Educ Online. 2023 Dec;28(1):2259166. doi: 10.1080/10872981.2023.2259166. Epub 2023 Sep 18.ABSTRACTResearch suggests that medical students are not confident and may be ill-prepared to prescribe competently. Therefore, changes to standard education may be required to fortify medical student prescribing skills, confidence, and competence. However, specific education to write a safe and legal prescription is generally lacking. Furthermore, the term prescribe and the skill thereof is not clearly defined. This review compares additional education for medical students to no identified additional education or another education...
Source: Medical Education Online - September 18, 2023 Category: Universities & Medical Training Authors: Sophie M Mokrzecki Andrew Mallett Tarun Sen Gupta Stephen Perks Tilley Pain Source Type: research
Regulation of nociception threshold by norepinephrine through adrenergic α2 receptor in rat models of Parkinson's disease
CONCLUSIONS: The change of norepinephrine content can affect the activation of prefrontal and cingulate gyrus glial cells and participate in the regulation of nociception threshold in PD rats. Adrenergic α2 receptor agonist and central presynaptic membrane α2 receptor blocker both affect cell activation and improve hyperalgesia.PMID:37721421 | DOI:10.1111/cns.14446
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Qing Gao Yingying Zhang Xiaoying Wang Rui Wang Limei Zhang Source Type: research
Effects of breathing exercises on chronic low back pain: A systematic review and meta-analysis of randomized controlled trials
CONCLUSION: Breathing exercises can reduce pain, assist people with lumbar disabilities, and improve pulmonary function, and could be considered as a potential alternative treatment for CLBP.PMID:37718775 | DOI:10.3233/BMR-230054
Source: Journal of Back and Musculoskeletal Rehabilitation - September 18, 2023 Category: Orthopaedics Authors: Xiaoyu Jiang Wenyu Sun Qiang Chen Qiling Xu Guoming Chen Hongyan Bi Source Type: research
Long-COVID-19 clinical and health outcomes: an umbrella review
CONCLUSION: This study confirmed a high prevalence of several long COVID-19 outcomes according to the MedDRA categories and indicated that the majority of evidence was rated as moderate to low.REGISTRATION: The review was registered at PROSPERO (https://www.crd.york.ac.uk/prospero/) (CRD42022303557).PMID:37720384 | PMC:PMC10501084 | DOI:10.1177/20499361231198335
Source: Adv Data - September 18, 2023 Category: Epidemiology Authors: Hu Li Jin Xia Dimitri Bennett Fatima Roque Rujuta A Bam Ana B árbara Tadeu Tavares Mugdha Gokhale Fidelia Ida Jinnie Jiwon Rhee Montse Soriano Gabarro Yiqing Song Source Type: research
Inhibition of PP2A ameliorates intervertebral disc degeneration by reducing annulus fibrosus cells apoptosis via p38/MAPK signal pathway
CONCLUSIONS: This study suggests that the downregulation of PP2 A could reduce AF cell apoptosis and degeneration via the p38/MAPK pathway. It also revealed that the inhibition of PP2 A is expected to be a therapeutic target for IVDD.PMID:37722489 | DOI:10.1016/j.bbadis.2023.166888
Source: Biochimica et Biophysica Acta - September 18, 2023 Category: Biochemistry Authors: Pengfei Zhu Xiexing Wu Li Ni Kai Chen Zhongchen Dong Jiacheng Du Fanchen Kong Yubo Mao Huaqiang Tao Miao Chu Haiqin Mao Huilin Yang Qinbai Liu Minfeng Gan Dechun Geng Source Type: research
Attitudes and Practices Surrounding Opioid Prescriptions following Open Reduction Internal Fixation of Distal Radius and Ankle Fractures: A Survey of the Canadian Orthopaedic Association Membership
CONCLUSIONS: The principle finding of this study is the lack of a standardized approach to postoperative prescribing in distal radius and ankle fractures, illustrated by the wide range in number of opioids prescribed by Canadian orthopaedic surgeons. Our data suggest a trend towards overprescription among respondents following distal radius and ankle ORIF. Future studies should aim to rationalize interventions targeted at reducing postoperative opioid prescribing for common orthopaedic trauma procedures.PMID:37719667 | PMC:PMC10501842 | DOI:10.1155/2023/9968219
Source: Adv Data - September 18, 2023 Category: Epidemiology Authors: Jihad A Abouali Evan D Curd Xin Y Mei Ujash Sheth Moin Khan Darren de Sa Vehniah K Tjong Jesleen Rana Source Type: research
Melatonin as preemptive analgesic for intraoperative pain
This study evaluates the efficacy of using melatonin and ketorolac for pain prevention during open-flap debridement surgery. This prospective randomized controlled trial was performed in patients who presented with chronic periodontitis after non-surgical periodontal therapy, requiring flap surgery. Group 1: Flap surgery following non-surgical periodontal therapy after one month with no oral administration of analgesic. Group 2: Flap surgery following non-surgical periodontal therapy after one month with oral administration of Ketorolac 400mg one hour prior to the surgery. Group 3: Flap surgery following non-surgical perio...
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Chanchal Katariya Sankari Malaiappan Source Type: research
Discovery of (S)-flurbiprofen-based novel azine derivatives as prostaglandin endoperoxide synthase-II inhibitors: Synthesis, in-vivo analgesic, anti-inflammatory activities, and their molecular docking
Bioorg Chem. 2023 Sep 12;141:106847. doi: 10.1016/j.bioorg.2023.106847. Online ahead of print.ABSTRACTThe anti-inflammatory and analgesic drugs currently used are associated with several adverse effects and found to be highly unsafe for long-term use. Currently, nineteen novel bis-Schiff base derivatives (1-19) of flurbiprofen have been designed, prepared and assessed for in-vivo analgesic, anti-inflammatory and in vivo acute toxicity evaluation. The structures of the acquired compounds were deduced through modern spectroscopic techniques including HR-ESI-MS, 13C-, and 1H NMR. Amongst the series, compounds 7, 9, and 10 att...
Source: Bioorganic Chemistry - September 18, 2023 Category: Chemistry Authors: Aftab Alam Mumtaz Ali None Zainab Abdul Latif Najeeb Ur Rehman Abdul Jabbar Shah Irfan Amir Khan Muhammad Ayaz Sajjad Ur Rahman Ahmed Al-Harrasi Manzoor Ahmad Source Type: research
Integration of palliative care in the management of oral squamous cell carcinoma
Bioinformation. 2023 Jan 31;19(1):1-4. doi: 10.6026/97320630019001. eCollection 2023.ABSTRACTOral Squamous cell Cancers (OSCC) is strongly associated with tobacco consumption. We here in present a case study of a OSCC patient who refused standard oncological care (SOC), to highlight the importance of integrating palliative care (PC) for improved patient outcomes. A 61 years male patient, with history of chewing tobacco for more than 20 years and diagnosed to have OSCC for 1.5 years presented with severe anaemia and a cauliflower-like growth (12 x 10 cm) in the left oral cavity and cheek with greenish-yellow discharge. Pus ...
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Republica Sridhar Huwait Etimad Peter Natesan Pushparaj Gauthaman Kalamegam Source Type: research
