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Key elements determining the intestinal region-specific environment of enteric neurons in type 1 diabetes
World J Gastroenterol. 2023 May 14;29(18):2704-2716. doi: 10.3748/wjg.v29.i18.2704.ABSTRACTDiabetes, as a metabolic disorder, is accompanied with several gastrointestinal (GI) symptoms, like abdominal pain, gastroparesis, diarrhoea or constipation. Serious and complex enteric nervous system damage is confirmed in the background of these diabetic motility complaints. The anatomical length of the GI tract, as well as genetic, developmental, structural and functional differences between its segments contribute to the distinct, intestinal region-specific effects of hyperglycemia. These observations support and highlight the im...
Source: World Journal of Gastroenterology : WJG - June 5, 2023 Category: Gastroenterology Authors: M ária Bagyánszki Nikolett B ódi Source Type: research
