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Total 80 results found since Jan 2013.

Global reading processes in children with high risk of dyslexia: a scanpath analysis
Ann Dyslexia. 2022 Feb 11:1-23. doi: 10.1007/s11881-021-00251-z. Online ahead of print.ABSTRACTThe study presents the first systematic comparison of the global reading processes via scanpath analysis in Russian-speaking children with and without reading difficulties. First, we compared basic eye-movement characteristics in reading sentences in two groups of children in grades 1 to 5 (N = 72 in high risk of developmental dyslexia group and N = 72 in the control group). Next, using the scanpath method, we investigated which global reading processes these children adopt to read the entire sentence and how these processes diff...
Source: Annals of Dyslexia - February 11, 2022 Category: Neurology Authors: Olga Parshina Anastasiya Lopukhina Sofya Goldina Ekaterina Iskra Margarita Serebryakova Vladislava Staroverova Nina Zdorova Olga Dragoy Source Type: research

Audio-visual stimulation for visual compensatory functions in stroke survivors with visual field defect: a systematic review
ConclusionSystematic AV training may improve the processing of visual information by recruiting subcortical pathways, and because most of the patients with visual cortex damage have an intact SC, it might be useful to use the bimodal AV training to activate retinotectal functions. Nevertheless, the underlying mechanisms supporting the reported positive effects are not currently understood. Systematic functional and/or structural imaging studies may help in understanding the underlying mechanism and inform the design of optimal training paradigms.
Source: Neurological Sciences - February 11, 2022 Category: Neurology Source Type: research

Case Report: Semantic Variant of Primary Progressive Aphasia Associated With Anti-Glial Fibrillary Acid Protein Autoantibodies
ConclusionWe diagnosed a svPPA in this patient and report an association between serum anti-GFAP antibodies and svPPA never reported in the literature so far, thereby expanding the clinical spectrum of svPPA and anti-GFAP-antibody related disease. Further research is needed to elucidate the underlying immunopathology of this disease entity to ultimately improve treatment.
Source: Frontiers in Immunology - January 3, 2022 Category: Allergy & Immunology Source Type: research

Whole-genome sequencing identifies functional noncoding variation in SEMA3C that cosegregates with dyslexia in a multigenerational family
AbstractDyslexia is a common heritable developmental disorder involving impaired reading abilities. Its genetic underpinnings are thought to be complex and heterogeneous, involving common and rare genetic variation. Multigenerational families segregating apparent monogenic forms of language-related disorders can provide useful entrypoints into biological pathways. In the present study, we performed a genome-wide linkage scan in a three-generational family in which dyslexia affects 14 of its 30 members and seems to be transmitted with an autosomal dominant pattern of inheritance. We identified a locus on chromosome 7q21.11 ...
Source: Human Genetics - June 2, 2021 Category: Genetics & Stem Cells Source Type: research

Difficulty learning nonsense words may indicate a child's high risk of dyslexia
(Aalto University) A combined brain-scanning and behaviour study in Finland has explored dyslexia in 7& 8-year-old children learning how to read. Dyslexic youngsters were shown to have different activation in the left hemisphere compared to the control group - the area of the brain that specializes in processing language and speech. A related study by the group also found that self-confidence in reading ability helps young readers overcome some of the symptoms of dyslexia
Source: EurekAlert! - Medicine and Health - March 19, 2021 Category: International Medicine & Public Health Source Type: news

Correlation between diffusion tensor imaging measures and the reading and cognitive performance of Arabic readers: dyslexic children perspective
ConclusionWhite matter microstructural DTI measurements in the right AF, right PLIC, SLF, and left anterior and superior CR are correlated to reading, spelling, writing, memory, and rapid naming abilities of the participants. The DTI measures could be promising regarding their use as a biomarker for follow-up in developmental dyslexia.
Source: Neuroradiology - January 17, 2020 Category: Radiology Source Type: research

Neuropsychological Functioning and Temperament Traits in a Czech Sample of Children and Adolescents at Familial Risk of Bipolar Disorder
Conclusions: Neuropsychological impairment does not seem to be a trait marker of BD in the premorbid stage. Temperament with low effortful control and low attention focusing might be associated with the development of mood disorders in BO. Introduction Children of parents with bipolar disorder (BD), i.e., bipolar offspring (BO), have an increased risk of developing the disorder than offspring of mentally healthy parents (control offspring; CO), with an estimated heritability of 59% (1). The clinical staging model for BD was developed to improve early interventions and to prevent its onset (2, 3). BO with no symptoms ...
Source: Frontiers in Psychiatry - April 8, 2019 Category: Psychiatry Source Type: research

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia, Published online: 11 February 2019; doi:10.1038/s41398-019-0402-0Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
Source: Translational Psychiatry - February 11, 2019 Category: Psychiatry Authors: Alessandro Gialluisi Till F. M. Andlauer Nazanin Mirza-Schreiber Kristina Moll Jessica Becker Per Hoffmann Kerstin U. Ludwig Darina Czamara Beate St Pourcain William Brandler Ferenc Honbolyg ó D énes Tóth Val éria Csépe Guillaume Huguet Andrew P. Mor Source Type: research

Reading without words or target detection? A re-analysis and replication fMRI study of the Landolt paradigm
AbstractThe Landolt paradigm is a visual scanning task intended to evoke reading-like eye-movements in the absence of orthographic or lexical information, thus allowing the dissociation of (sub-) lexical vs. visual processing. To that end, all letters in real word sentences are exchanged for closed Landolt rings, with 0, 1, or 2 open Landolt rings as targets in each Landolt sentence. A preliminary fMRI block-design study (Hillen et al. in Front Hum Neurosci 7:1 –14, 2013) demonstrated that the Landolt paradigm has a special neural signature, recruiting the right IPS and SPL as part of the endogenous attention network. Ho...
Source: Anatomy and Embryology - August 30, 2018 Category: Anatomy Source Type: research

MRI shows link between radiation and memory loss in kids
MRI scans have shown how the effects of radiation therapy can reduce the volume...Read more on AuntMinnie.comRelated Reading: Soccer ball heading more risky for women than men MRI shows how kids compensate for dyslexia MRI shows the uniqueness of brain anatomy DTI-MRI finds abnormal brain connections in autistic kids fMRI offers clues about memory loss in older adults
Source: AuntMinnie.com Headlines - August 20, 2018 Category: Radiology Source Type: news

No evidence for cerebellar abnormality in adults with developmental dyslexia.
In conclusion, no support for the cerebellar deficit hypothesis or the presence of anatomical differences of the cerebellum in adults with developmental dyslexia was found. PMID: 30116863 [PubMed - as supplied by publisher]
Source: Experimental Brain Research - August 16, 2018 Category: Neuroscience Authors: van Oers CAMM, Goldberg N, Fiorin G, van den Heuvel MP, Kappelle LJ, Wijnen FNK Tags: Exp Brain Res Source Type: research