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Total 2470 results found since Jan 2013.

Comparison of Clinical Manifestations of Kawasaki Disease According to SARS-CoV-2 Antibody Positivity
CONCLUSION: High incidence of intravenous immunoglobulin-refractory KD may occur in up to 40% of the patients having recent history of coronavirus disease 2019. For patients having KD with N-type SARS-CoV-2 antibody positivity, adjunctive treatment, such as corticosteroids, can be considered as the first line of treatment.PMID:37337806 | PMC:PMC10279516 | DOI:10.3346/jkms.2023.38.e181
Source: J Korean Med Sci - June 20, 2023 Category: General Medicine Authors: Jin Ho Kim Jihye You Source Type: research

Controller therapy attenuates asthma exacerbations associated with prior SARS-CoV-2 infection in children
Abbreviations: Coronavirus disease 2019 (COVID-19); severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), angiotensin-converting enzyme 2 (ACE2), transmembrane serine protease 2 (TMPRSS2), inhaled corticosteroids (ICS), oral corticosteroid (OCS), short-acting beta-agonist (SABA), long-acting beta-agonist (LABA), leukotriene receptor antagonist (LTRA), rate ratios (RR), polymerase chain reaction (PCR)
Source: Annals of Allergy, Asthma and Immunology - June 12, 2023 Category: Allergy & Immunology Authors: Iris Kim, Tricia Morphew, Christine Chou, Louis Ehwerhemuepha, Stanley Galant Tags: Letters Source Type: research

COVID-19 Associated Mucormycosis
AbstractMucormycosis is a life-threatening opportunistic fungal infection seen in immunocompromised states. Rising incidence of mucormycosis among Coronavirus Disease-2019 infected individuals is an increasing concern in India. The disease which was endemic has blown out to become an epidemic. The purpose of this research is to study the epidemiology, management and outcome of Coronavirus Disease-2019 Associated Mucormycosis (CAM) cases. Additionally, the role of diabetes and steroids in the causation of CAM was determined. A hospital-based observational study was conducted at a tertiary care centre involving cases with rh...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - June 10, 2023 Category: ENT & OMF Source Type: research

Tocilizumab versus anakinra in COVID-19: results from propensity score matching
ConclusionOur study showed comparable efficacy and safety profiles of tocilizumab and anakinra to treat severe COVID-19.
Source: Frontiers in Immunology - May 26, 2023 Category: Allergy & Immunology Source Type: research

Case report: Unusual patient with dermatomyositis associated with SARS-CoV-2 infection
This study aimed to present a previously healthy 37-year-old man, a soldier by profession, with symptoms of DM on the 4th day from the onset of COVID-19. The patient presented DM symptoms with both skin and muscle manifestations. The patient suffered from cough, fever, and fatigue to begin with, and reverse-transcription polymerase chain reaction (RT-PCR) reported positive for SARS-CoV-2 infection. The laboratory findings showed, intra alia, elevated muscle enzymes CK 8253 U/l (N: <145 U/l), a positive test for myositis-specific autoantibodies (anti-Mi-2), electrodiagnostic tests exhibited features of myopathy, with the...
Source: Frontiers in Neurology - May 19, 2023 Category: Neurology Source Type: research

Novel targeted inhibition of the IL-5 axis for drug reaction with eosinophilia and systemic symptoms syndrome
ConclusionCurrent treatment guidelines for DRESS are based on case reports and expert opinion. Understanding the central role of eosinophils in DRESS pathogenicity emphasizes the need for future implementation of IL-5 axis blockade as steroid-sparing agents, potential therapy to steroid-resistant cases, and perhaps an alternative to CS treatment in certain DRESS patients more prone to CS toxicity.
Source: Frontiers in Immunology - April 28, 2023 Category: Allergy & Immunology Source Type: research

Newly diagnosed extranodal NK/T-cell lymphoma, nasal type, at the injected left arm after BNT162b2 mRNA COVID-19 vaccination
Int J Hematol. 2023 Apr 24. doi: 10.1007/s12185-023-03607-w. Online ahead of print.ABSTRACTAnti-SARS-CoV-2 vaccines were developed in response to the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the BNT162b2 mRNA vaccine is effective, adverse effects have been reported. Here, we report a case of extranodal NK/T-cell lymphoma, nasal type (ENKL), of the left arm following BNT162b2 mRNA vaccination. A 73-year-old male presented with a lump in the left arm, which was the site where he received the BNT162b2 mRNA vaccine 3 months prior. He was treat...
Source: International Journal of Hematology - April 24, 2023 Category: Hematology Authors: Takuto Tachita Takenori Takahata Satoru Yamashita Toru Ebina Kosuke Kamata Kazufumi Yamagata Yoshiko Tamai Hirotake Sakuraba Source Type: research

Who is the convict; COVID ‐19 or corticosteroid? Late onset avascular necrosis of hips after COVID‐19. A case report with literature review
ConclusionAn awareness of the possible osteonecrosis for all physicians dealing with patients with musculoskeletal problems following COVID-19 is necessary.
Source: International Journal of Rheumatic Diseases - April 24, 2023 Category: Rheumatology Authors: Mohammad Nejadhosseinian, Hoda Haerian, Marzie Tabatabaie  Nejad, Kourosh Sadeghi, Leila Aghaghazvini, Majid Alikhani, Maryam Loghman, Seyedeh Tahrerh Faezi Tags: CASE REPORT Source Type: research

COVID-19 Developed During Systemic Steroid Therapy for Vogt-Koyanagi-Harada Disease: A Case Report
CONCLUSION: Given the absence of international agreement on how to manage COVID-19 patients with steroid-dependent VKH, existing clinical guidelines should be reviewed thoroughly to formulate useful strategies for managing VKH patients on steroid treatment who contract COVID-19. Furthermore, the outcomes of patients with steroid-dependent autoimmune uveitis including VKH who develop COVID-19 should be analyzed.PMID:37084286 | DOI:10.1080/09273948.2023.2200488
Source: Ocular Immunology and Inflammation - April 21, 2023 Category: Allergy & Immunology Authors: Shoichiro Niidome Yoshihiko Usui Kinya Tsubota Risa Sugawara Hiroshi Goto Source Type: research