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Total 558 results found since Jan 2013.
Is It Time for Ocrelizumab Extended Interval Dosing in Relapsing Remitting MS? Evidence from An Italian Multicenter Experience During the COVID-19 Pandemic
AbstractIn the COVID-19 pandemic era, safety concerns have been raised regarding the risk of severe infection following administration of ocrelizumab (OCR), a B-cell-depleting therapy. We enrolled all relapsing remitting multiple sclerosis (RRMS) patients who received maintenance doses of OCR from January 2020 to June 2021. Data were extracted in December 2021. Standard interval dosing (SID) was defined as a regular maintenance interval of OCR infusion every 6 months, whereas extended interval dosing (EID) was defined as an OCR infusion delay of at least 4 weeks. Three infusions were considered in defining SID vs. EID (...
Source: Neurotherapeutics - August 29, 2022 Category: Neurology Source Type: research
Isolated abducens nerve palsy following AstraZeneca vaccine: A case report
We present a case of a 72-year-old female who presented with sudden right abducens nerve palsy after receiving the 2nd dose of booster vaccine following the AstraZeneca COVID-19 vaccine. Because of the temporal association between vaccination and abducens nerve palsy, they assumed her vaccine caused it. The onset of symptoms, the absence of any prior medical conditions, and normal magnetic resonance imaging. This case highlights the importance of determining whether a COVID-19 vaccine could generate neurologic side effects similar to those found with the virus and previous vaccinations.PMID:35999834 | PMC:PMC9388279 | DOI:...
Source: Annals of Medicine - August 24, 2022 Category: Internal Medicine Authors: Krity Basnet Rupa Bhandari Kushal Basnet Ananta Aryal Reshma Shrestha Source Type: research
Cardiac involvement in coronavirus disease 2019 assessed by cardiac magnetic resonance imaging: a meta-analysis
AbstractIn this systematic review and meta-analysis, we sought to evaluate the prevalence of cardiac involvement in patients with COVID-19 using cardiac magnetic resonance imaging. A literature review was performed to investigate the left ventricular (LV) and right ventricular (RV) ejection fraction (EF), the prevalence of LV late gadolinium enhancement (LGE), pericardial enhancement, abnormality on T1 mapping, and T2 mapping/T2-weighted imaging (T2WI), and myocarditis (defined by modified Lake Louis criteria). Pooled mean differences (MD) between COVID-19 patients and controls for LVEF and RVEF were estimated using random...
Source: Heart and Vessels - August 4, 2022 Category: Cardiology Source Type: research
Computed tomography and magnetic resonance imaging for pulmonary embolus evaluation in children: up-to-date review on practical imaging protocols
This article provides guidance for up-to-date CT and MR imaging techniques, reviews key recent studies on the imaging of pediatric PE, and discusses relevant pediatric PE imaging pearls and pitfalls, in hopes of providing readers with up-to-date and accurate practice for imaging evaluation of PE in children.
Source: Pediatric Radiology - July 22, 2022 Category: Radiology Source Type: research
Chronic biopsy proven post-COVID myoendocarditis with SARS-Cov-2 persistence and high level of antiheart antibodies
CONCLUSIONS: COVID-19 can lead to long-term severe post-COVID myoendocarditis, that is characterized by prolonged persistence of coronavirus in cardiomyocytes, endothelium, and macrophages (up to 18 months) in combination with high immune activity. Corticosteroids and anticoagulants should be considered as a treatment option of post-COVID myoendocarditis.PMID:35855554 | DOI:10.1002/clc.23886
Source: Atherosclerosis - July 20, 2022 Category: Cardiology Authors: Olga Blagova Yuliya Lutokhina Evgenia Kogan Anna Kukleva Dilara Ainetdinova Vladimir Novosadov Ruslan Rud' Polina Savina Alexander Zaitsev Viktor Fomin Source Type: research
Imaging markers of neurologic damage in COVID-19: a systematic review
CONCLUSION: The heterogeneity of the studies precludes any generalization of the findings. Brain MRI is the most informative imaging exam. Population studies including the entire spectrum of COVID-19 are missing. There is still a need for future population studies evaluating neurologic manifestations of all COVID-19 severities acutely and chronically.PMID:35786328 | DOI:10.2174/0929867329666220701124945
Source: Current Medicinal Chemistry - July 5, 2022 Category: Chemistry Authors: Sara Tavares Ara újo Clara Tavares Ara újo Rafael Silva E Castro Lara Machado de Oliveira Br ügger Nath ália Gualberto Souza E Silva Debora Marques de Miranda Ana Cristina Sim ões E Silva Source Type: research
Neurological disorders in COVID-19: a case of Acute Disseminated Encephalomyelitis in an adult patient
Acta Biomed. 2022 Jun 29;93(S1):e20222140. doi: 10.23750/abm.v93iS1.12885.ABSTRACTDifferent neurological complications associated with the severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection have been widely documented. Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated demyelinating disorder, described within the spectrum of neurological manifestations of COVID-19. Herein, we describe a case of adult-ADEM presenting with diplopia and slowly progressive ataxia developed one month after SARS-CoV-2 infection. Brain magnetic resonance imaging (MRI) revealed acute multifocal demyelinating le...
Source: Acta Bio-Medica : Atenei Parmensis - June 29, 2022 Category: General Medicine Authors: Lorenzo Verriello Sara Pez Giada Pauletto Serena D'Agostini Annacarmen Nilo Gian Luigi Gigli Mariarosaria Valente Source Type: research
A fatal case coronavirus disease 2019 & #8211; Associated acute hemorrhagic necrotizing encephalopathy
Abdoulahy Diallo, Yacouba Dembele, Mohamadou Niang, Lucas Balloy, François Pousset, Issifou Yaya, Sarah PermalJournal of Global Infectious Diseases 2022 14(2):84-86
Coronavirus disease 2019 (COVID-19) has been reported in association with a variety of brain imaging findings such as acute hemorrhagic necrotizing encephalopathy. To the best of our knowledge, we are reporting a second case of acute necrotizing hemorrhagic encephalopathy associated with COVID-19, which was fatal in a few hours in a 56-year-old male without a specific history. We claim that this case is important because this case shows that the un...
Source: Journal of Global Infectious Diseases - June 29, 2022 Category: Infectious Diseases Authors: Abdoulahy Diallo Yacouba Dembele Mohamadou Niang Lucas Balloy Fran & #231;ois Pousset Issifou Yaya Sarah Permal Source Type: research
Course of Cardiac Magnetic Resonance Imaging Findings in Acute Myocarditis after COVID-19 mRNA Vaccination
Intern Med. 2022 Jun 21. doi: 10.2169/internalmedicine.9797-22. Online ahead of print.ABSTRACTMyocarditis is being increasingly reported as a rare complication of coronavirus disease 2019 (COVID-19) mRNA vaccines. We herein report a case of myocarditis following COVID-19 mRNA vaccination in a man. Cardiac magnetic resonance imaging (CMRI) revealed an area of high signal intensity on short T1 inversion recovery (STIR) and late gadolinium enhancement (LGE), which are characteristic of myocarditis. Follow-up CMRI performed six months later revealed improvement in the myocardial edema and LGE findings. CMRI is a useful non-inv...
Source: Internal Medicine - June 22, 2022 Category: Internal Medicine Authors: Hirotaka Kawauchi Yuya Mitsuhasi Shin Nakamura Risa Ogawa Tomonori Miyabe Ken Kato Hiroyuki Tanaka Source Type: research
