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Infectious Disease: Gastroenteritis

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Total 42073 results found since Jan 2013.

Evidence-based optimisation of empirical antibiotic regimens in paediatric complicated appendicitis: a retrospective study of 94 patients
CONCLUSION: This retrospective study demonstrated a decrease in the rate of postoperative infectious complications due to amoxicillin-clavulanate-resistant E. coli in complicated appendicitis. These findings accentuate the need to implement evidence-based treatment protocols based on local microbiology profiles and resistance rates to optimise post-operative antibiotics in complicated appendicitis.PMID:36102072 | DOI:10.4414/smw.2022.w30222
Source: Swiss Medical Weekly - September 14, 2022 Category: General Medicine Authors: Filippo Gerber Jean-Marc Joseph Pierre-Alex Crisinel V éronique Andrey Source Type: research

A CURE on the Evolution of Antibiotic Resistance in < em > Escherichia coli < /em > Improves Student Conceptual Understanding
CBE Life Sci Educ. 2023 Mar;22(1):ar7. doi: 10.1187/cbe.21-12-0331.ABSTRACTWe developed labs on the evolution of antibiotic resistance to assess the costs and benefits of replacing traditional laboratory exercises in an introductory biology course for majors with a course-based undergraduate research experience (CURE). To assess whether participating in the CURE imposed a cost in terms of exam performance, we implemented a quasi-experiment in which four lab sections in the same term of the same course did the CURE labs, while all other students did traditional labs. To assess whether participating in the CURE impacted othe...
Source: CBE Life Sciences Education - January 6, 2023 Category: Cytology Authors: Scott Freeman Joya Mukerji Matt Sievers Ismael Barreras Beltran Katie Dickinson Grace E C Dy Amanda Gardiner Elizabeth H Glenski Mariah J Hill Ben Kerr Deja Monet Connor Reemts Elli Theobald Elisa T Tran Vicente Velasco Lexi Wachtell Liz Warfield Source Type: research

Antimicrobial Activity of Gepotidacin Tested against Escherichia coli and Staphylococcus saprophyticus Isolates Causing Urinary Tract Infections in Medical Centers Worldwide (2019 to 2020)
Antimicrob Agents Chemother. 2023 Mar 6:e0152522. doi: 10.1128/aac.01525-22. Online ahead of print.ABSTRACTThe in vitro activities of gepotidacin and comparator agents against 3,560 Escherichia coli and 344 Staphylococcus saprophyticus collected from female (81.1%) and male (18.9%) patients with urinary tract infections (UTIs) in a global prospective surveillance program in 2019 to 2020 were determined. Isolates collected from 92 medical centers in 25 countries, including the United States, Europe, Latin America, and Japan, were tested for susceptibility by reference methods in a central monitoring laboratory. Gepotidacin ...
Source: Antimicrobial Agents and Chemotherapy - March 6, 2023 Category: Microbiology Authors: S J Ryan Arends Deborah Butler Nicole Scangarella-Oman Mariana Castanheira Rodrigo E Mendes Source Type: research

A high affinity and specificity anti-HER2 single-domain antibody (VHH) that targets trastuzumab's epitope with versatile biochemical, biological, and medical applications
Immunol Res. 2023 Aug 26. doi: 10.1007/s12026-023-09418-9. Online ahead of print.ABSTRACTIn the past decade, various single-domain antibodies from llamas, also known as VHH or nanobody, have been discovered with applications in tumor imaging and cancer therapy. However, the potential application of anti-HER2 VHHs as a diagnostic tool suitable for ELISA, flow cytometry, cell imaging, bispecific antibody engineering, and immunohistochemistry has not been fully elucidated. To investigate this potential, HER2 antigen was expressed in HEK293 F cells, purified, and used to immunize llama. Using phage display, anti-HER2 VHHs with...
Source: Cell Research - August 26, 2023 Category: Cytology Authors: Shahryar Khoshtinat Nikkhoi Hediyeh Heydarzadeh Venu Gopal Vandavasi Ge Yang Pedro Louro Marianne Polunas Hajar Owji Arash Hatefi Source Type: research

The impact of EHR and HIE on reducing avoidable admissions: controlling main differential diagnoses
Conclusions: Viewing medical history via an EHR IS and using HIE network led to a reduction in the number of seven day readmissions and single-day admissions for all patients. Using external medical history may imply a more thorough patient examination that can help eliminate unnecessary admissions. Nevertheless, in most instances physicians did not view medical history at all, probably due to the limited resources available, combined with the stress of rapid turnover in ED units.
Source: BMC Medical Informatics and Decision Making - Latest articles - April 17, 2013 Category: Information Technology Authors: Ofir Ben-AssuliItamar ShabtaiMoshe Leshno Source Type: research

Emergence of community-acquired extended-spectrum beta-lactamase Escherichia coli (ESBLEC) in Honolulu: a case series of three individuals with community-acquired ESBLEC bacteriuria
Hawaii Med J. 2011 Sep;70(9):193-5.ABSTRACTCommunity-acquired extended-spectrum beta-lactamase E coli (ESBLEC) have not been previously described in Honolulu. Its emergence as a community-acquired pathogen is concerning. This case series describes three patients who were diagnosed with community-acquired ESBLEC bacteriuria in 2010.PMID:22162614 | PMC:PMC3233400
Source: Hawaii Medical Journal - December 14, 2011 Category: General Medicine Authors: Reid R Hoshide Heath Chung Jinichi Tokeshi Source Type: research