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Infectious Disease: Gastroenteritis
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Amino acid-mediated negatively charged surface improve antifouling and tribological characteristics for medical applications
In this study, we developed an antifouling surface composed of biocompatible amino acids (leucine, taurine, and aspartic acid) on polyimide, via modification using a series of facile immersion steps with waterborne reactions. The naturally derived amino acid could be formed highly biostable amide bonds on the polyimide surface like peptides. The amino acid-modified surface formed a water layer with antifouling performance through the hydrophilic properties of amino acids. Amino acid-mediated modification reduced adhesion up to 84.45% and 94.81% against Escherichia coli and Staphylococcus epidermidis, respectively, and exhi...
Source: Colloids and Surfaces - January 16, 2022 Category: Biotechnology Authors: Dong Uk Lee Dong Won Kim Seung Yeup Lee Dong Yun Choi Seung Yong Choi Kyoung-Seok Moon Min Young Shon Myung Jun Moon Source Type: research
Antibacterial and anti-inflammatory activities of chitosan/copper complex coating on medical catheters: In vitro and in vivo
J Biomed Mater Res B Appl Biomater. 2022 Mar 7. doi: 10.1002/jbm.b.35047. Online ahead of print.ABSTRACTCopper ions (Cu) grafted chitosan coating was prepared using the pneumatic spraying method on the silicone rubber surface. Coating's surface properties, morphology, composition, Cu releasing behavior, antibacterial, and anti-inflammatory activities are investigated and discussed. Surface properties, composition, and morphology were investigated by scanning electron microscopy (SEM) and contact angle measurements. The antibacterial activity has been tested with Escherichia coli and Staphylococcus aureus suspensions in vit...
Source: Biomed Res - March 7, 2022 Category: Research Authors: Guisong Gu Deniz Eren Eri şen Ke Yang Bingchun Zhang Minggang Shen Jingyu Zou Xun Qi Shanshan Chen Xiaohe Xu Source Type: research
Evidence-based optimisation of empirical antibiotic regimens in paediatric complicated appendicitis: a retrospective study of 94 patients
CONCLUSION: This retrospective study demonstrated a decrease in the rate of postoperative infectious complications due to amoxicillin-clavulanate-resistant E. coli in complicated appendicitis. These findings accentuate the need to implement evidence-based treatment protocols based on local microbiology profiles and resistance rates to optimise post-operative antibiotics in complicated appendicitis.PMID:36102072 | DOI:10.4414/smw.2022.w30222
Source: Swiss Medical Weekly - September 14, 2022 Category: General Medicine Authors: Filippo Gerber Jean-Marc Joseph Pierre-Alex Crisinel V éronique Andrey Source Type: research
