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Infectious Disease: Gastroenteritis
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Infliximab rescue therapy in a patient with acute severe ulcerative colitis and coronavirus disease 2019 followed by Escherichia coli 0157:H7 infection: a case report
We report on the first case of a patient with acute severe ulcerative colitis and mild coronavirus disease 2019 (COVID-19) who received rescue infliximab therapy, followed by a relapse caused by enterohemorrhagic Escherichia coli 0157:H7. The treatment challenges we faced were biologic therapy administration during active COVID-19, about which little was known at the time, and how to treat EHEC due to the risk of hemolytic uremic syndrome. Acute severe ulcerative colitis was treated with rescue infliximab therapy, and enteric infection with an antibiotic, both with satisfactory clinical response. The decision to induce bio...
Source: Croatian Medical Journal - January 4, 2022 Category: General Medicine Authors: Dinko Beki ć Željka Belošić Halle Source Type: research
Gut microbiome composition in pre-adolescent children with different meat consumption patterns
CONCLUSION: The preference of red meat and white meat consumption may significantly reduce the abundance and diversity of gut microbiota in pre-adolescent children. A red meat-rich diet may cause enrichment of Escherichia-Shigella and significant activation of lipopolysaccharide biosynthesis pathway, suggesting the potential benefit of a balanced diet for pre-adolescent children.PMID:35012911 | PMC:PMC8752432 | DOI:10.12122/j.issn.1673-4254.2021.12.07
Source: Journal of Southern Medical University - January 11, 2022 Category: Universities & Medical Training Authors: Q Lin J Lun J Zhang X He Z Gong X Gao H Cao Source Type: research
Infliximab rescue therapy in a patient with acute severe ulcerative colitis and coronavirus disease 2019 followed by Escherichia coli 0157:H7 infection: a case report
We report on the first case of a patient with acute severe ulcerative colitis and mild coronavirus disease 2019 (COVID-19) who received rescue infliximab therapy, followed by a relapse caused by enterohemorrhagic Escherichia coli 0157:H7. The treatment challenges we faced were biologic therapy administration during active COVID-19, about which little was known at the time, and how to treat EHEC due to the risk of hemolytic uremic syndrome. Acute severe ulcerative colitis was treated with rescue infliximab therapy, and enteric infection with an antibiotic, both with satisfactory clinical response. The decision to induce bio...
Source: Croatian Medical Journal - January 4, 2022 Category: General Medicine Authors: Dinko Beki ć Željka Belošić Halle Source Type: research
Gut microbiome composition in pre-adolescent children with different meat consumption patterns
CONCLUSION: The preference of red meat and white meat consumption may significantly reduce the abundance and diversity of gut microbiota in pre-adolescent children. A red meat-rich diet may cause enrichment of Escherichia-Shigella and significant activation of lipopolysaccharide biosynthesis pathway, suggesting the potential benefit of a balanced diet for pre-adolescent children.PMID:35012911 | PMC:PMC8752432 | DOI:10.12122/j.issn.1673-4254.2021.12.07
Source: Journal of Southern Medical University - January 11, 2022 Category: Universities & Medical Training Authors: Q Lin J Lun J Zhang X He Z Gong X Gao H Cao Source Type: research
Construction and identification of a HEK293 cell line with stable TrxR1 overexpression
CONCLUSION: We successfully obtained a HEK293 cell line with stable TrxR1 overexpression, which shows resistance to auranofin and can be used for screening TrxR1 targeting drugs.PMID:35527491 | PMC:PMC9085581 | DOI:10.12122/j.issn.1673-4254.2022.04.11
Source: Journal of Southern Medical University - May 9, 2022 Category: Universities & Medical Training Authors: X L ü Z Zhou L Zhu J Zhou H Huang C Zhang X Liu Source Type: research
