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Total 1260 results found since Jan 2013.
Wharton's Jelly Mesenchymal Stem Cells-derived Exosomes and Imipenem in Combination Reduce Apoptosis and Inflammatory Responses in E.coli-infected HepG2 Cells
In this study, we investigated the immunomodulatory effect of Wharton's jelly MSC-derived exosomes in combination with imipenem on HepG2 cells infected with Escherichia col i.MSC-derived exosomes were separated from MSCs, which were isolated by flow cytometry. Scanning electron microscopy and dynamic light scanning were used to confirm the presence of exosomes. Quantitative real-time PCR, ELISA, and nitric oxide assay were used to assess the inflammatory response in the infected cells. Annexin-PI was used to measure the extent of apoptosis. The results showed that the combination of imipenem and MSC-derived exosomes were m...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 13, 2022 Category: Allergy & Immunology Authors: Ali Hazrati Sara Soudi Seyed Mahmoud Hashemi Source Type: research
Cough Presentation and Cough-Related Healthcare Utilization in Tertiary Care: Analysis of Routinely Collected Academic Institutional Database
ConclusionsCough is a common chief complaint at allergy and asthma clinics, but the clinical presentation may be heterogeneous. Further studies are needed to understand long-term outcomes and reduce the disease burden.
Source: Lung - July 9, 2022 Category: Respiratory Medicine Source Type: research
Indications for Absorbable Steroid ‐Eluting Sinus Implants: Viewpoint via the Delphi Method
Source: International Forum of Allergy and Rhinology - June 22, 2022 Category: Allergy & Immunology Authors: Victoria S. Lee,
Prayag Patel,
Daniel O'Brien,
George A. Scangas,
Raewyn G. Campbell,
Rakesh Chandra,
Greg E. Davis,
Joseph K Han,
Christopher H. Le,
Jivianne Lee,
Amber U. Luong,
David M. Poetker,
Hassan Ramadan,
Michael Setzen,
Kristine Sm Tags: VIEWPOINT Source Type: research
Could Transthoracic Ultrasound be useful to suggest a small airways disease in severe uncontrolled asthma?
CONCLUSION: TUS in severe uncontrolled asthma patients can provide useful information on the state of the peripheral lung, suggesting the execution of a second-line HRCT scan for better assessment of eventual alterations that may represent underlying causes of non-response to treatment.PMID:35643297 | DOI:10.1016/j.anai.2022.05.024
Source: Annals of Allergy, Asthma and Immunology - June 1, 2022 Category: Allergy & Immunology Authors: By Giulia Scioscia Donato Lacedonia Carla Maria Irene Quarato Pasquale Tondo Anna Del Colle Marco Sperandeo Giovanna Elisiana Carpagnano Maria Pia Foschino Barbaro Source Type: research
Race and Ethnicity Define Disparate Clinical Outcomes in Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) is a common inflammatory disease of the upper airways and is a significant health burden in all racial groups in the United States1. Rhinosinusitis is clinically defined as inflammation of the nose and the paranasal sinuses characterized by sinonasal symptoms combined with objective signs of disease identified by endoscope or Computed Tomography (CT) scan2. Patients with symptoms that persist for more than 12 weeks are diagnosed with CRS2,3. It has been found that CRS affects 1% to 5% of the U.S.
Source: Annals of Allergy, Asthma and Immunology - May 23, 2022 Category: Allergy & Immunology Authors: Evelyn Konsur, Lauren Rigg, Donyea Moore, Malina Patel, Pete S. Batra, Mahboobeh Mahdavinia Tags: Original Article Source Type: research
A case of febrile infection-related epilepsy syndrome (FIRES) in young adult: still a diagnostic and therapeutic challenge
We report a case of acute encephalopathy with refractory seizures after a febrile illness (FIRES) in a young adult with complete remission of symptoms as well as dramatic improvement of EEG abnormalities following intravenous immunoglobulin and proper antiepileptic medications. We con ducted an extensive workup including lumbar puncture, blood tests, EEG serial monitoring, MRI brain, total body CT scan, and PET brain with FDG to shed light on the etiology of the disease.
Source: Neurological Sciences - May 4, 2022 Category: Neurology Source Type: research
