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Total 276 results found since Jan 2013.

Inadequacy of current pediatric epinephrine autoinjector needle length for use in infants and toddlers.
CONCLUSION: Our data suggest that the optimal EAI needle length for infants and toddlers weighing 7.5 to 15 kg should be shorter than the needle length in currently available pediatric EAIs to avoid accidental intraosseous injections. PMID: 28483294 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 5, 2017 Category: Allergy & Immunology Authors: Kim H, Dinakar C, McInnis P, Rudin D, Benain X, Daley W, Platz E Tags: Ann Allergy Asthma Immunol Source Type: research

Long-term Multimodal Therapy (Verapamil Associated with Propolis, Blueberry, Vitamin E and local Diclofenac) on Patients with Peyronie's Disease (Chronic Inflammation of the Tunica Albuginea ). Results of a Controlled Study.
CONCLUSION: Our results showed that a long-term multimodal medical therapy (Verapamil associated with Propolis, Blueberry, Vitamin E and local Diclofenac) is statistically effective in treating PD, whereas, lower therapeutic responses were obtained after 6 months treatment (medium-term treatment). Furthermore, this study strongly supports the recommendation that the best approach for treating PD is multimodal therapy. PMID: 24304332 [PubMed - as supplied by publisher]
Source: Inflammation and Allergy Drug Targets - December 4, 2013 Category: Allergy & Immunology Authors: Paulis G, Cavallini G, Giorgio GD, Quattrocchi S, Brancato T, Alvaro R Tags: Inflamm Allergy Drug Targets Source Type: research

A novel method for comparison of tissue fibrosis after inferior turbinate surgery: Ultrasound elastography.
CONCLUSION: Both RFA and SBD of the inferior turbinates were effective in inducing scar tissue and, eventually, fibrosis in the soft tissue of inferior turbinates. Cauterization has been found to cause significantly higher amounts of fibrosis than radiofrequency; however, it did not reflect the comparable clinical outcome. This is the first study that objectively and noninvasively evaluates the targeted tissue fibrosis of the inferior turbinate surgeries by the novel inferior turbinate US elastography. PMID: 25590315 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2015 Category: ENT & OMF Authors: Gode S, Turhal G, Kismali E, Ozturk K, Midilli R Tags: Am J Rhinol Allergy Source Type: research

Epinephrine auto-injector needle lengths can both subcutaneous and periosteal/intraosseous injection be avoided?
CONCLUSION: Common HPEAIs have a high risk of periosteal/intraosseous penetration in children and subcutaneous injections in overweight and obese adults. The LPEAIs have some risk of subcutaneous injection in adults. HPEAIs 0.1 mg epinephrine and shorter needle has no risk of periosteal/intraosseous injection but a high risk of subcutaneous deposit. For use in adult, over-weight/obese patients, HPEAIs and LPEAIs should have longer needles. Future studies should focus on the triggering pressures and the variations in needle length. PMID: 29499370 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - February 27, 2018 Category: Allergy & Immunology Authors: Dreborg S, Kim L, Tsai G, Kim H Tags: Ann Allergy Asthma Immunol Source Type: research

Epinephrine, auto-injectors and anaphylaxis: challenges of dose, depth and device.
CONCLUSION: EAIs should be available in the community with doses and needle depths that meet the needs of all patients. More research on epinephrine pharmacodynamics are needed in children and adults in anaphylaxis, in order to better delineate what optimal doses should be. Optimizing epinephrine dose and delivery has the potential to improve anaphylaxis outcomes and prevent adverse events. PMID: 29746901 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 7, 2018 Category: Allergy & Immunology Authors: Brown J Tags: Ann Allergy Asthma Immunol Source Type: research

Premedication of pregnant patients with history of iodinated contrast allergy
Abstract Pregnant patients can receive allergy premedication prior to a contrast-enhanced computed tomography exam if the exam is indicated. The risks and benefits of allergy premedication for pregnant patients will be discussed, as well as imaging strategies for the pregnant patient with a contrast allergy. Alternative imaging including ultrasound, noncontrast magnetic resonance imaging, or noncontrast computed tomography can be diagnostic depending on the clinical scenario and is usually preferred, allowing physicians to avoid giving allergy premedication in pregnancy, a 13  h delay, and risking a breakthrough reaction.
Source: Abdominal Imaging - July 21, 2016 Category: Radiology Source Type: research

Mast cell diseases in patients with insect venom allergy: implications for diagnosis and therapy
ConclusionThe determination of baseline serum tryptase (bST) and an examination of the skin are recommended in all adult patients with a  previous history of systemic sting reactions. Patients with mastocytosis of the skin and/or bST elevated above 20 µg/l should always undergo further investigation. If bST is elevated in the absence of mastocytosis, or if a more accurate diagnosis of the mast cell disease is relevant, a so-cal led liquid biopsy can be performed, enabling a KIT mutation (tyrosine kinase receptor) to be investigated in peripheral blood. Bone marrow biopsy, bone density measurement, and upper abdomina...
Source: Allergo Journal International - May 4, 2017 Category: Allergy & Immunology Source Type: research

Intravascular Ultrasound-Guided Cardiac Intervention in a Fontan Patient with Allergy to Contrast Media.
We describe the case of a 16-year-old boy who presented with fatigue and cyanosis. He had undergone a Fontan operation 14 years previously, after which he developed an allergy to iodinated contrast media. Contrast echocardiograms by manual injection of microbubbles suggested the presence of a venovenous collateral vessel from the brachiocephalic vein draining into the pulmonary vein. We used intravascular ultrasound as the sole imaging method to identify the target vessel and to guide deployment of an Amplatzer Vascular Plug II. The patient experienced immediate improvement in his systemic saturation. Our experience shows ...
Source: Texas Heart Institute Journal - October 1, 2017 Category: Cardiology Authors: Muneuchi J, Okada S, Nagatomo Y, Iida C, Matsuoka R, Shirozu M, Watanabe M Tags: Tex Heart Inst J Source Type: research

Intralymphatic Immunotherapy: Update and Unmet Needs
Allergen-specific immunotherapy (AIT) is the only allergy treatment that confers long-term symptom amelioration for patients suffering from allergy. The most frequently used allergen application route is subcutaneous injection (SCIT), commonly taken as the gold standard, followed by sublingual (SLIT) or oral (OIT) application of allergen preparations. This is an up-to-date review of the clinical evidence for a novel route of allergen application, i.e., directly into lymph nodes – intralymphatic immunotherapy (ILIT). The major advantages of ILIT over the current AIT approaches are its short duration and the low allergen d...
Source: International Archives of Allergy and Immunology - November 2, 2018 Category: Allergy & Immunology Source Type: research

Cow's milk allergy: color Doppler ultrasound findings in infants with hematochezia.
CONCLUSION: Doppler US may be very useful in diagnosing secondary colitis, such as CMA, and to exclude several other abdominal diseases that can emulate this disease. PMID: 24035877 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - September 12, 2013 Category: Pediatrics Authors: Epifanio M, Spolidoro JV, Missima NG, Soder RB, Garcia PC, Baldisserotto M Tags: J Pediatr (Rio J) Source Type: research

Intralymphatic Immunotherapy improves grass pollen allergic rhinoconjunctivitis. A three-year randomized placebo-controlled trial
Ultrasound guided intralymphatic injections with grass allergen immunotherapy reduces allergy symptoms and use of rescue medicine in patients with grass pollen allergy over three years. The treatment consists of three injections and is completed within two months.
Source: Journal of Allergy and Clinical Immunology - July 13, 2020 Category: Allergy & Immunology Authors: S øren Helbo Skaarup., Johannes Martin Schmid., Tina Skjold., Ole Graumann., Hans Jürgen Hoffmann. Source Type: research

Diet of hookworms to tackle a bread allergy
James Logan, a biologist at the School of Hygiene and Tropical Medicine also tried leeches and is thinking about maggot therapy• Read about more scientists who go to extremes lengthsA lot of people don't realise that just one metre below your feet walking along Gower Street or Malet Street in London, you have thousands upon thousands of very hungry, potentially dangerous insects.In the basement we have our insectary colonies where we keep lots of different species of mosquitoes, found in all parts of the world. None of them are infected with malaria, but they are in very high numbers. We also have bed bugs, house dust mi...
Source: Guardian Unlimited Science - December 1, 2013 Category: Science Authors: Josh Davis Tags: Allergies Health Medical research Society Technology Features Animals Insects The Observer Environment Science Wildlife Source Type: news

Cows Milk Allergy: A Cohort of Patients from a University Hospital.
Abstract The study illustrates advantages of Fiberoptic Bronchoscopy, a new service started at St. Lukes General Hospital in patient care since April 2014. Retrospective review of Bronchoscopies and referrals to Tertiary care unit for Bronchoscopy, prior and after initiation of service at St. Lukes Hospital were studied. Total 106 procedures were performed out of which 103(98%) were for diagnostic purpose. Common Indications for bronchoscopy were functional airway assessment in 38 cases (35%) of chronic cough, 26 cases (24.8%) of suspected Malignancy. The average time taken for procedure was 15 + 1 minute with ove...
Source: Ir Med J - October 1, 2016 Category: Journals (General) Authors: Reynolds A, O'Driscoll J, Quinn S, Coughlan D Tags: Ir Med J Source Type: research

Ultrasound-based transient elastography improves the detection of liver disease in common variable immunodeficiency
Publication date: September–October 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 7Author(s): Antonio Pecoraro, Ludovica Crescenzi, Andrea Fiorentino, Filomena Morisco, Giuseppe Spadaro
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 5, 2019 Category: Allergy & Immunology Source Type: research

Assessment of Airway Remodeling Using Endobronchial Ultrasound in Asthma-COPD Overlap
Source: Journal of Asthma and Allergy - June 13, 2021 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research