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Total 1034 results found since Jan 2013.

Allergy testing in children with persistent asthma: Comparison of four diagnostic methods
ConclusionThe high prevalence of food and respiratory sensitization supports the clinical guideline recommendation that allergies should be evaluated in all children with suspected asthma. The microarray platforms studied here demonstrated acceptable accuracy and provided refined IgE characterization in 47% of the patients compared to standard extract‐based methods.This article is protected by copyright. All rights reserved.
Source: Allergy - September 16, 2016 Category: Allergy & Immunology Authors: Annica Önell, Anna Whiteman, Björn Nordlund, Francesca Baldracchini, Giorgio Mazzoleni, Gunilla Hedlin, Hans Grönlund, Jon R Konradsen Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Prenatal tobacco exposure and risk of asthma and allergy outcomes in childhood
Conclusion Prenatal tobacco exposure was associated with asthma dependent on 17q12-21 genotype and with exacerbations, lung function and bronchial responsiveness, but not with any allergy-related outcomes. This suggests that tobacco exposure in utero leads to adverse lung developmental/structural effects rather than susceptibility to develop allergy and type 2 inflammation.
Source: European Respiratory Journal - February 17, 2022 Category: Respiratory Medicine Authors: Sunde, R. B., Thorsen, J., Pedersen, C.-E. T., Stokholm, J., Bonnelykke, K., Chawes, B., Bisgaard, H. Tags: Asthma and allergy, Paediatric pulmonology Original Articles: Asthma and paediatrics Source Type: research

The Montelukast Therapy in Asthmatic Children with and without Food Allergy: Does It Make Any Difference?
Conclusion: Although children with FAA do not show a more favorable response to montelukast treatment compared to AA, a significant difference between baseline PGD2 and CystLT levels between FAA and AA groups may point to a different endotype of childhood asthma.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - September 9, 2021 Category: Allergy & Immunology Source Type: research

Severe childhood asthma and allergy to furry animals: Refined assessment using molecular‐based allergy diagnostics
ConclusionChildren with severe allergic asthma had higher sIgE levels to cat, dog and horse. Molecular‐based allergy diagnostics revealed a more complex molecular spreading of allergen components in children with the most severe disease.
Source: Pediatric Allergy and Immunology - December 1, 2013 Category: Allergy & Immunology Authors: Jon R. Konradsen, Björn Nordlund, Annica Onell, Magnus P. Borres, Hans Grönlund, Gunilla Hedlin Tags: Original Article Source Type: research

Allergy symptoms in personnel from a museum complex
Conclusions: The bioaerosols in the workplace air might induce the diagnosed allergenic symptoms. This is supported by the significantly higher prevalence of elevated serum Ig in exposed. The allergenic potential of the workplace air should be monitored and reduced.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Gradinariu, F., Danulescu, E., Croitoru, C., MARGINEANU, M., Ipate, M. Tags: 5.3 Allergy and Immunology Source Type: research

Decreased Sensitization to Aeroallergens among Southwestern Iranian Male Farmers.
Abstract Farmers are usually exposed to various inhaled allergens like pollens, mites, molds, and animal dander in their working environment which may lead to allergic rhinitis, asthma and urticaria. The purpose of this study was to identify sensitization to various aeroallergens in farmers and their occupational allergy symptoms. This cross sectional study included 103 male farmers and 100 non-farmer healthy controls. The work-related symptoms of farmers were recorded with a questionnaire. Spirometry and skin prick tests with 15 commercial allergen extracts were performed in both farmers and controls. The rate of...
Source: Iranian Journal of Allergy, Asthma and Immunology - August 1, 2017 Category: Allergy & Immunology Authors: Moghtaderi M, Torab Jahromi M, Farjadian S, Ghassemi P, Hosseini Teshnizi S Tags: Iran J Allergy Asthma Immunol Source Type: research

Oral immunotherapy in cow's milk allergic patients: course and long-term outcome according to asthma status.
CONCLUSION: Patients with asthma are at risk for more severe reactions and are less likely to reach full desensitization during food oral immunotherapy. However, most reach limited daily consumption and most who achieve full desensitization continue to consume milk protein freely after treatment. PMID: 25595888 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - January 14, 2015 Category: Allergy & Immunology Authors: Elizur A, Goldberg MR, Levy MB, Nachshon L, Katz Y Tags: Ann Allergy Asthma Immunol Source Type: research

Letter to the Editor: Can dog allergen immunotherapy reduce concomitant allergic sensitization to other furry animals? A preliminary experience.
We describe a case of dog allergy in which we explored if dog AIT (DAI) could reduce a concomitant allergic sensitization to other allergens of furry animals. Our case demonstrates the efficacy of sublingual DAI on SPTs, symptom score, and spirometric responses despite persistent exposure to dog allergens at home in a patient sensitized, but not exposed, to several other furry animals. Moreover, this is the first report suggesting that DAI is able to reduce SPTs responses not only to dog, but also to other furry animals such as rabbit, horse, mouse, rat, hamster, cow. We recommend an accurate anamnesis and diagnosis of dog...
Source: European Annals of Allergy and Clinical Immunology - March 23, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

The effects of vitamin D supplementation on airway functions in mild to moderate persistent asthma.
CONCLUSION: Vitamin D supplementation associated with asthma controllers could significantly improve FEV1 in mild to moderate persistent asthma after 24 weeks. TRIAL REGISTRATION: irct.ir Identifier: IRCT201302079608N1. PMID: 25091714 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - August 1, 2014 Category: Allergy & Immunology Authors: Arshi S, Fallahpour M, Nabavi M, Bemanian MH, Javad-Mousavi SA, Nojomi M, Esmaeilzadeh H, Molatefi R, Rekabi M, Jalali F, Akbarpour N Tags: Ann Allergy Asthma Immunol Source Type: research

Neutrophil-like low-density granulocytes are elevated in patients with moderate to severe persistent asthma.
CONCLUSION: These findings identify a previously unrecognized association between LDG levels and asthma severity. Identification of the factor(s) responsible for the increased LDG levels in moderate persistent or SP asthma may provide a serum biomarker to aid in the identification of neutrophil-associated phenotypes of severe asthma. PMID: 25256681 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - September 23, 2014 Category: Allergy & Immunology Authors: Fu J, Tobin MC, Thomas LL Tags: Ann Allergy Asthma Immunol Source Type: research

Relation of lung function and current inhalant allergen-specific immunoglobulin E concentrations in adolescents (GINIplus cohort).
CONCLUSION: Although allergen-specific IgE concentrations can contribute to the identification of subjects at higher risk for allergic rhinitis and asthma, sensitization to inhalant allergens is not related to impaired spirometric lung parameters within the different allergic respiratory disease subgroups. PMID: 26195441 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 17, 2015 Category: Allergy & Immunology Authors: Luzak A, Flexeder C, von Berg A, Berdel D, Klümper C, Koletzko S, Bauer CP, Heinrich J, Nowak D, Schulz H Tags: Ann Allergy Asthma Immunol Source Type: research

The Safety of Nasal Allergen Challenge Test Assessed in Lower Airways.
Abstract The aim of the study was to assess the safety of nasal allergen challenge, and the use of certain parameters applied in assessing the condition of the respiratory system. We enrolled 30 patients diagnosed with allergy to common environmental allergens and 30 healthy controls. The safety of nasal challenge tests with an allergen was assessed by measuring the concentration of exhaled nitric oxide from the lower respiratory tract (eNO) and forced expiratory volume in one second (FEV1) in a spirometry test. In the early phase of the allergic reaction, extra-nasal symptoms were observed, namely cough and bre...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 1, 2015 Category: Allergy & Immunology Authors: Krzych-Falta E, Piekarska B, Sybilski A, Wojas O, Samoliński B Tags: Iran J Allergy Asthma Immunol Source Type: research

Factors correlated with repeated aspirin dosing during aspirin desensitization.
CONCLUSION: During aspirin desensitization for AERD, approximately 1/3 of our patients require multiple repeat doses. Risk factors for multiple repeated doses include male gender, drop in FEV1, and lower aspirin provoking doses during desensitization. This information can help inform which patients might require multiple re-dosing for desensitization. PMID: 29653235 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 10, 2018 Category: Allergy & Immunology Authors: Schuler CF, Baldwin JL, Baptist AP Tags: Ann Allergy Asthma Immunol Source Type: research

Prevalence, Risk Factors and Cutoff Values for Bronchial Hyperresponsiveness to Provocholine in 7-Year-Old Children.
CONCLUSIONS: BHR to Provocholine (PC20 < 8 mg/mL) was observed in 17.2% of 7-year-olds children from the general population and the cutoff value of PC20 for the diagnosis of current asthma was 5.8 mg/mL in this age group. The risk factors for BHR and current asthma showed discrepancies suggesting different underlying mechanisms. Bronchial provocation testing with Provocholine will be a useful clinical tool in the future. PMID: 30088367 [PubMed]
Source: Allergy, Asthma and Immunology Research - August 10, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Telemedicine for Allergy Services to Rural Communities
Publication date: Available online 22 June 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Luisa Taylor, Morgan Waller, Jay PortnoyAbstractTelemedicine (TM) involves the use of technology to provide medical services to patients who live at a distance. It can be used asynchronously for interpretation of tests (spirometry, skin tests imaging studies), and for communication of information when the simultaneous presence of provider and patient is unnecessary. Synchronous encounters can be either unscheduled and initiated on-demand by patients or they can be facilitated substitutes for in-perso...
Source: The Journal of Allergy and Clinical Immunology: In Practice - June 24, 2019 Category: Allergy & Immunology Source Type: research