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Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization.
CONCLUSIONS: CHI3L1 plays a pivotal role in Th2 inflammation and M2 macrophage polarization through MAPK/ERK and PI3K/AKT phosphorylation in food allergy.
PMID: 32935492 [PubMed]
Source: Allergy, Asthma and Immunology Research - September 18, 2020 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
CONCLUSION: In conclusion, chitinases can be used as potential biomarkers in prognosis and diagnosis of several inflammatory diseases and allergies and the design of novel chitinase inhibitors may act as key and rational scaffolds in designing of some novel therapeutic agents in the treatment of variety of inflammatory diseases.
PMID: 31934842 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - January 15, 2020 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research
Teal Pumpkins Help Make Halloween Food Allergy-Friendly
DRACUT (CBS) — One in thirteen kids has a potentially life-threatening food allergy, which can make Halloween downright frightening.
But this year, there’s a way to tell which homes are safe for all kids: Teal pumpkins.
Instead of carving, pumpkins, Joan Powers and her kids – 5-year-old Jack and 4-year-old Tessa of Dracut, are painting their pumpkins. Teal is the color of food allergy awareness, something the Powers family knows a lot about.
Jack is allergic to synthetic food dye — anything that has a color with a number after it. Tessa is allergic to shellfish.
There’s not much to worry about with a shel...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 29, 2014 Category: Consumer Health News Authors: nealjriley Tags: Health Local News Seen On WBZ-TV Syndicated Local CBS Boston Dr. Mallika Marshall Food Allergies Food Allergy Research and Education teal pumpkins Source Type: news
Allergy evaluation of hypersensitivity to platinium salts and taxanes: a six-year experience.
ConclusionsST to PS or TX offered a high NPV, making allergy evaluation a key element in the management of cancer patients. Graded challenges can be safely performed by oncology teams trained in anaphylaxis management.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 7, 2020 Category: Allergy & Immunology Source Type: research
Effects of antioxidant supplements and nutrients on patients with asthma and allergies
Asthma and allergic diseases have become a worldwide public health concern because of their increased prevalence. Despite decades of research on risk factors, the causes of these disorders are poorly understood. They are thought to develop through complex interactions between genetic and environmental factors. Because pulmonary and systemic oxidative stress increase inflammatory responses relevant to asthma and allergy, dietary or vitamin supplementation with antioxidants (a broad and varied category) has been proposed as an approach to reducing asthma incidence or morbidity. Meta-analyses of observational epidemiologic st...
Source: Journal of Allergy and Clinical Immunology - April 28, 2014 Category: Allergy & Immunology Authors: Hortensia Moreno-Macias, Isabelle Romieu Tags: Clinical reviews in allergy and immunology Source Type: research
Epidemiological associations of allergy, IgE and cancer
This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - July 1, 2013 Category: Allergy & Immunology Authors: Debra H. Josephs, James F. Spicer, Christopher J. Corrigan, Hannah J. Gould, Sophia N. Karagiannis Tags: Invited Review Source Type: research
Probiotics in Curing Allergic and Inflammatory Conditions - Research Progress and Futuristic Vision.
CONCLUSION: Present review gives an insight towards potent utility of this branch of beneficial microbial therapy in allergy and inflammations, which is still in the emerging phase and more scientific evidences need to be explored regarding exploration of the mechanisms of action, further experimental trials and validation of controlled clinical studies in humans along with designing novel strategies for monitoring the possible microbial changes in their composition and metabolism associated with their interaction upon host immune system.
PMID: 28029082 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - December 29, 2016 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research
Physicians' experience and opinion on contraindications to allergen immunotherapy: The CONSIT survey.
CONCLUSION: Major problems were infrequent and experienced physicians were less likely to be restrictive in the use of AIT.
PMID: 28477792 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - May 1, 2017 Category: Allergy & Immunology Authors: Rodríguez Del Rio P, Pitsios C, Tsoumani M, Pfaar O, Paraskevopoulos G, Gawlik R, Valovirta E, Larenas-Linnemann D, Demoly P, Calderón MA Tags: Ann Allergy Asthma Immunol Source Type: research
AllergoOncology: Opposite Outcomes of Immune Tolerance in Allergy and Cancer
This article is protected by copyright. All rights reserved.
Source: Allergy - September 17, 2017 Category: Allergy & Immunology Authors: E Jensen ‐Jarolim, H J Bax, R Bianchini, S Crescioli, T R Daniels‐Wells, D Dombrowicz, E Fiebiger, H J Gould, S Irshad, J Janda, D H Josephs, F Levi‐Schaffer, L O′Mahony, G Pellizzari, M L Penichet, F Redegeld, F Roth‐Walter, J Singer, E Untersm Tags: Position Paper Source Type: research
Food Allergy Detection Device Could Remove Danger Of Dining Out
BOSTON (CBS) – Clare Maloney-Kolenberg is high school junior from Winchester who is looking forward to traveling to Spain on an exchange program with her Spanish class.
But that excitement is coupled with a bit of anxiety due to her food allergies. “I’m allergic to tree nuts, peanuts and sesame,” she told WBZ-TV.
It’s a list that can make dining out a bit dicey, even in familiar restaurants near home. But once you add unfamiliar foods and a language barrier, that increases the odds of a reaction.
That’s exactly what happened when Clare ordered ice cream on a trip to Germany with her family.
“All of a s...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 7, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local Dr. Mallika Marshall Food Allergy Detection Device Source Type: news
Are Registration of Disease Codes for Adult Anaphylaxis Accurate in the Emergency Department?
CONCLUSIONS: In case of anaphylaxis, more patients were registered inaccurately under other allergy-related codes and symptom-related codes rather than accurately under anaphylaxis disease codes. Cardiovascular symptoms, severe symptoms, and epinephrine treatment were factors associated with accurate registration with anaphylaxis disease codes in patients with anaphylaxis.
PMID: 29411554 [PubMed]
Source: Allergy, Asthma and Immunology Research - February 8, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Allergic Contact Dermatitis To Fentanyl TTS With Good Tolerance To Systemic Fentanyl.
CONCLUSION: We present the case of allergic contact dermatitis (ACD) due to hypersensitivity to fentanyl with good tolerance to buprenorphine. Positive PT in this patient suggests a type IV hypersensitivity mechanism. Allergic reactions to opioids are frequently immediate, but delayed reactions could appear, especially when the drug is administered topically.
PMID: 31131754 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - May 29, 2019 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research
Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity, Relationships, Second Edition
The second edition of the book Drug Allergy is a comprehensive textbook that encompasses the most current knowledge on drug allergy and hypersensitivity. The authors note that “the general applicability of drug allergy in modern medicine in itself emphasizes the need for an integrated text that treats the subject in its own right.” The need to update the first edition is described as owing to the continued development and innovation of biological and targeted therapie s with application to cancer, autoimmunity, and metabolic disorders, with increased adverse effects and capable of inducing hypersensitivity and allergic reactions.
Source: Annals of Allergy, Asthma and Immunology - March 28, 2022 Category: Allergy & Immunology Authors: Mariana Castells Tags: Book Review Source Type: research
Allergy-cancer connection discovered
While many are stocking up on allergy medicine in preparation for spring, a new study from researchers at Virginia Commonwealth University Massey Cancer Center has uncovered a new connection between allergy and cancer that could potentially lead to therapies involving common antihistamines.Recently published in the Journal of Leukocyte Biology, the study was led by Daniel H. Conrad, Ph.D., member of the Cancer Cell Signaling research program at Massey and professor of microbiology and immunology at the VCU School of Medicine, with substantial contributions from Ph.D.
Source: Health News from Medical News Today - March 22, 2014 Category: Consumer Health News Tags: Allergy Source Type: news
Immunoglobulin Glycosylation Effects in Allergy and Immunity
AbstractPurpose of ReviewThe aim of this review will be to familiarize the reader with the general area of antibody (Ab) glycosylation and to summarize the known functional roles of glycosylation and how glycan structure can contribute to various disease states with emphasis on allergic disease.Recent FindingsBoth immunoglobulin (Ig) isotype and conserved Fc glycosylation sites often dictate the downstream activity of an Ab where complexity and degree of glycosylation contribute to its ability to bind Fc receptors (FcRs) and activate complement. Most information on the effects of glycosylation center on IgG in cancer thera...
Source: Current Allergy and Asthma Reports - October 30, 2016 Category: Allergy & Immunology Source Type: research
