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Infectious Disease: Herpes
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Total 364 results found since Jan 2013.
Effect of Disease Severity on Comorbid Conditions in Atopic Dermatitis: Nationwide Registry-Based Investigation in Finnish Adults
Acta Derm Venereol. 2023 Mar 8;103:adv00882. doi: 10.2340/actadv.v103.4447.ABSTRACTThe majority of registry studies on atopic dermatitis include only patients and diagnoses from specialized healthcare. The aim of this retrospective, real-world cohort study was to evaluate the effect of atopic dermatitis severity on comorbidities and total morbidity, with comprehensive data from both primary and specialty healthcare registries covering the entire Finnish adult population. In total, 124,038 patients were identified (median age 46 years; 68% female) and stratified by disease severity. All regression analyses (median follow-up...
Source: Acta Derm Venereol A... - March 8, 2023 Category: Dermatology Authors: Ville Kiiski Liisa Ukkola-Vuoti Johanna Vikkula Martta Ranta Mariann I Lassenius Jaakko Kopra Source Type: research
Incidence of Herpes Zoster in Patients with Asthma Compared to Patients without Asthma: A Retrospective Database Study
This study sought to estimate the incidence of HZ in patients with asthma and compared to patients without asthma.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: David Singer, Philippe Thompson-Leduc, Deepshekhar Gupta, Siyu Ma, Wendy Cheng, Manasvi Sundar, Ella Hagopian, Mei Sheng Duh, John Oppenheimer Source Type: research
Differences in IgG autoantibody Fab glycosylation across autoimmune diseases
CONCLUSION: Our data indicate that in chronic but not acute B cell-mediated autoimmune diseases disease-specific autoantibodies are enriched for Fab glycans.PMID:36716825 | DOI:10.1016/j.jaci.2022.10.035
Source: Herpes - January 30, 2023 Category: Infectious Diseases Authors: Jana Koers Rocco Sciarrillo Ninotska I L Derksen Esther M Vletter Yvonne E Filli é-Grijpma Elisabeth Raveling-Eelsing Nuno A G Gra ça Thiemo Leijser Hendri H Pas L Laura van Nijen-Vos Maaike V J Braham Anne-Marie Buisman Jan de Jong Angela I Schriek Ann Source Type: research
Sex and prior exposure jointly shape innate immune responses to a live herpesvirus vaccine
CONCLUSIONS: These results together show that prior exposure and sex interact to shape early innate responses that then impact subsequent adaptive immune phenotypes.FUNDING: Intramural Research Program of the NIH, the National Institute of Allergy and Infectious Diseases, and other institutes supporting the Trans-NIH Center for Human Immunology, Autoimmunity, and Inflammation. The vaccine trial was supported through a clinical trial agreement between the National Institute of Allergy and Infectious Diseases and Sanofi Pasteur. Clinical trial number: NCT01915212.PMID:36648132 | DOI:10.7554/eLife.80652
Source: Herpes - January 17, 2023 Category: Infectious Diseases Authors: Foo Cheung Richard Apps Lesia Dropulic Yuri Kotliarov Jinguo Chen Tristan Jordan Marc Langweiler Julian Candia Angelique Biancotto Kyu Lee Han Nicholas Rachmaninoff Harlan Pietz Kening Wang John S Tsang Jeffrey I Cohen Source Type: research
Science ’s 2022 Breakthrough of the Year: A telescope’s golden eye sees the universe anew
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Source: ScienceNOW - December 15, 2022 Category: Science Source Type: news
What Are the Potential Benefits and Risks of Premasticated Foods?
Discussion
Premastication is the prechewing of foods or medicines by another person before feeding to an infant. It is also used to pretaste or temperature test foods. It was a common practice for millennia, especially before modern food technology, as a way to transition an infant from a solely liquid based diet to a mixed diet mainly of solid food. Rates of premastication vary, with less developed countries having an increased incidence/prevalence (up to 50%) but it is not uncommon in developed countries (in the US 14% is reported).
Saliva is also used to clean other people, treat cuts/itches or insect bites as well. Pla...
Source: PediatricEducation.org - November 14, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Impact of universal testing and treatment on sexual risk behaviour and herpes simplex virus type 2: a prespecified secondary outcomes analysis of the HPTN 071 (PopART) community-randomised trial
Lancet HIV. 2022 Nov;9(11):e760-e770. doi: 10.1016/S2352-3018(22)00253-3.ABSTRACTBACKGROUND: Comprehensive HIV prevention strategies have raised concerns that knowledge of interventions to reduce risk of HIV infection might mitigate an individual's perception of risk, resulting in riskier sexual behaviour. We investigated the prespecified secondary outcomes of the HPTN 071 (PopART) trial to determine whether a combination HIV prevention strategy, including universal HIV testing and treatment, changed sexual behaviour; specifically, we investigated whether there was evidence of sexual risk compensation.METHODS: HPTN 071 (Po...
Source: Herpes - November 4, 2022 Category: Infectious Diseases Authors: Ethan Wilson Deborah Donnell Timothy Skalland Sian Floyd Ayana Moore Nomtha Bell-Mandla Justin Bwalya Nkatya Kasese Rory Dunbar Kwame Shanaube Barry Kosloff Oliver Laeyendecker Yaw Agyei Graeme Hoddinott Peter Bock Sarah Fidler Richard Hayes Helen Ayles H Source Type: research
Rare case of homozygous ifnar1 deficiency in a samoan child with disseminated varicella after vaccination
Autosomal recessive interferon alpha/beta receptor 1 (IFNAR1) deficiency increases susceptibility to live-attenuated vaccines and wild-type viruses. Currently 16 cases, half with Polynesian ancestry have been reported since the discovery in 2019. Most cases present with severe MMR or yellow fever vaccine-related disease. Some cases report severe SARS-CoV-2, herpes simplex, and enterovirus. Varicella vaccine-related disease has been hypothesized but not previously reported.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: M. Revier, N. Scanlon, M. Lee, C. Collins, S. Laubach Tags: M247 Source Type: research
Clinical and economic burden of herpes zoster in patients with asthma: a retrospective cohort study
This study estimated the incremental burden of HZ in patients with asthma.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: D. Singer, P. Thompson-Leduc, S. Ma, D. Gupta, W. Cheng, M. Duh, M. Bogart, J. Oppenheimer Tags: P104 Source Type: research
Painless herpes zoster in the setting of eosinophilia and markedly elevated ige levels
Herpes zoster (HZ) is a common condition caused by varicella zoster virus (VZV) reactivation. Typical malaise, fever, and localized paresthesias are followed by a dermatomal maculopapular eruption with eventual vesicles. HZ has been associated with eosinophilia, but not with elevation of IgE. The conditions most often associated with IgE elevations are typically rare. Here we describe an atypical case of painless HZ with eosinophilia and elevated IgE.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: A. Patel, E. Melkonian, S. Joshi, T. Bussineau, P. Patel Tags: M013 Source Type: research
Viral infections and drug hypersensitivity
Allergy. 2022 Oct 20. doi: 10.1111/all.15558. Online ahead of print.ABSTRACTVirus infections and T cell-mediated drug hypersensitivity reactions (DHR) can influence each other. In most instances, systemic virus infections appear first. They may prime the reactivity to drugs in two ways: First, by virus-induced second signals: certain drugs like β-lactam antibiotics are haptens and covalently bind to various soluble and tissue proteins, thereby forming novel antigens. Under homeostatic conditions, these neo-antigens do not induce an immune reaction, probably because co-stimulation is missing. During a virus infection, the ...
Source: Herpes - October 20, 2022 Category: Infectious Diseases Authors: Werner J Pichler Marie-Charlotte Br üggen Source Type: research
