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Infectious Disease: COVID-19
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Total 5132 results found since Jan 2013.
Health Status and Inconveniences of Asthmatic Children During the First Year of the COVID-19 Pandemic
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):245-253. doi: 10.18502/ijaai.v22i3.13052.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic has been the most significant health concern in recent years, with respiratory symptoms being the most prominent. In children, asthma is the most prevalent chronic disease. Due to the similarities between the symptoms of these two conditions, we sought to assess the general health status of pediatric patients with asthma and their COVID-19-related difficulties during the first year of the pandemic in Iran. We collected data for this study by administering a questionnaire to the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Saber Gharagozlou Negin Rostamzadeh Mohammad Gharagozlou Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
Health Status and Inconveniences of Asthmatic Children During the First Year of the COVID-19 Pandemic
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):245-253. doi: 10.18502/ijaai.v22i3.13052.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic has been the most significant health concern in recent years, with respiratory symptoms being the most prominent. In children, asthma is the most prevalent chronic disease. Due to the similarities between the symptoms of these two conditions, we sought to assess the general health status of pediatric patients with asthma and their COVID-19-related difficulties during the first year of the pandemic in Iran. We collected data for this study by administering a questionnaire to the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Saber Gharagozlou Negin Rostamzadeh Mohammad Gharagozlou Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
Senate panel approves 2% bump for NIH budget in 2024
To the relief of biomedical research advocates, a Senate spending panel has approved a modest budget increase of 2% for the National Institutes of Health (NIH). The bump to $47.8 billion roughly matches President Joe Biden’s request for the 2024 fiscal year that begins this fall. Although below the rate of biomedical inflation, it is far more generous than a corresponding House of Representatives bill that would
slash NIH’s budget by 6%
.
Advocacy groups welcomed the measure
approved
on 27 July by the Senate appropriations committee. “The Committee laid down an important marker for the appropriations...
Source: Science of Aging Knowledge Environment - July 28, 2023 Category: Geriatrics Source Type: research
Shared Pathogenicity Features and Sequences between EBV, SARS-CoV-2, and HLA Class I Molecule-binding Motifs with a Potential Role in Autoimmunity
AbstractEpstein-Barr virus (EBV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are extraordinary in their ability to activate autoimmunity as well as to induce diverse autoimmune diseases. Here we reviewed the current knowledge on their relation. Further, we suggested that molecular mimicry could be a possible common mechanism of autoimmunity induction in the susceptible individuals infected with SARS-CoV-2. Molecular mimicry between SARS-CoV-2 and human proteins, and EBV and human proteins, are present. Besides, relation of the pathogenicity associated with both coronavirus diseases and EBV supports the...
Source: Clinical Reviews in Allergy and Immunology - July 28, 2023 Category: Allergy & Immunology Source Type: research
Frequency of HLA-DR+CD38hi T cells identifies and quantifies T-cell activation in hemophagocytic lymphohistiocytosis, hyperinflammation, and immune regulatory disorders
Evaluation of T-cell activation is essential for the diagnosis of numerous hyperinflammatory and immune regulatory disorders, including hemophagocytic lymphohistiocytosis (HLH).1-6 Currently, plasma levels of soluble IL-2 receptor (sIL-2R) or sCD25/ αchain of the IL-2R complex are extensively used as a biomarker for measuring T-cell activation.7 Its role in the assessment of disease severity and monitoring has been established in a spectrum of hyperinflammatory disorders (HLH, multisystem inflammatory syndrome in children [MIS-C]),4,8,9 autoim mune disorders,10 infections (eg, HIV, EBV, coronavirus disease 2019 [COVID-19]...
Source: Journal of Allergy and Clinical Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Thinh H. Nguyen, Deepak Kumar, Chengyu Prince, Dylan Martini, Jocelyn R. Grunwell, Taylor Lawrence, Trenton Whitely, Karin Chappelle, Satheesh Chonat, Sampath Prahalad, Michael Briones, Shanmuganathan Chandrakasan Source Type: research
Environmental Risk Factors, Protective Factors, and Biomarkers for Allergic Rhinitis: A Systematic Umbrella Review of the Evidence
This study is registered in PROSPERO (CRD42022384320).
Source: Clinical Reviews in Allergy and Immunology - July 25, 2023 Category: Allergy & Immunology Source Type: research
Preference for and impact of telehealth vs in-person asthma visits among Black and Latinx adults
Black and Latinx adults experience disproportionate asthma-related morbidity and limited specialty care access. The severe acute respiratory syndrome coronavirus 2 pandemic expanded telehealth use.
Source: Annals of Allergy, Asthma and Immunology - July 23, 2023 Category: Allergy & Immunology Authors: Israel C. Ugalde, Amanda Ratigan, Conner Merriman, Jing Cui, Brianna Ericson, Paula Busse, Jennifer K. Carroll, Thomas Casale, Juan Carlos Celed ón, Tamera Coyne-Beasley, Maureen Fagan, Anne L. Fuhlbrigge, Gabriela Gaona Villarreal, Paulina Arias Hernand Source Type: research
The Direct Impact of the COVID ‐19 Pandemic on Rhinology Practice
ConclusionsCOVID-19 significantly affected the number of patients seen, virtual visit encounters, nasal endoscopies, and imaging utilization. Further research is needed to determine if patient outcomes were impacted and if these changes in practice will persist.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - July 22, 2023 Category: Allergy & Immunology Authors: Sarah R. Sutton,
April Taniguchi,
Shaun A. Nguyen,
Zachary M. Soler,
Rodney J. Schlosser Tags: CLINICAL LETTER Source Type: research
Explainer: Why the U.S. has banned funding for Chinese lab at center of pandemic origin dispute
In a move that has more symbolic than practical impact, the U.S. Department of Health and Human Services (HHS) has imposed new sanctions on a Chinese lab at the center of the debate about the origin of the COVID-19 pandemic.
A nine-page
HHS memo
made public by a House subcommittee that
’s investigating the pandemic
’s origin suspends and proposes debarment of the Wuhan Institute of Virology (WIV)
“from participating in United States Federal Government procurement and nonprocurement programs.” In effect, this bars WIV from receiving U.S. government funding now and possibly ever. The ...
Source: ScienceNOW - July 20, 2023 Category: Science Source Type: news
Profile of patients attending a pediatric allergic clinic during COVID-19 pandemic-related lockdown: how many children could have been approached with telemedicine?
Eur Ann Allergy Clin Immunol. 2023 Jul 18. doi: 10.23822/EurAnnACI.1764-1489.305. Online ahead of print.NO ABSTRACTPMID:37462039 | DOI:10.23822/EurAnnACI.1764-1489.305
Source: European Annals of Allergy and Clinical Immunology - July 18, 2023 Category: Allergy & Immunology Authors: A Ertugrul E Ulusoy Severcan H Arslan I Bostanc ı Source Type: research
