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Infectious Disease: Endemics
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Total 382 results found since Jan 2013.
Global View on Ant Venom Allergy: from Allergenic Components to Clinical Management
This article provides a global view on allergic reactions to the venoms of stinging ants and the contemporary approach to diagnose and manage ant venom allergy.
Source: Clinical Reviews in Allergy and Immunology - June 1, 2021 Category: Allergy & Immunology Source Type: research
Functional characterization of CD4+ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses
CONCLUSIONS Our data confirm, for what we believe is the first time, the existence of unique memory CD4+ T cell clonotypes crossrecognizing SARS-CoV-2 and CCCs. The lower avidity of crossreactive TCRs for SARS-CoV-2 may be the result of antigenic imprinting, such that preexisting CCC-specific memory T cells have reduced expansive capacity upon SARS-CoV-2 infection. Further studies are needed to determine how these crossreactive T cell responses affect clinical outcomes in COVID-19 patients.FUNDING NIH funding (U54CA260492, P30CA006973, P41EB028239, R01AI153349, R01AI145435-A1, R21AI149760, and U19A1088791) was provided by ...
Source: Journal of Clinical Investigation - May 18, 2021 Category: Biomedical Science Authors: Arbor G. Dykema, Boyang Zhang, Bezawit A. Woldemeskel, Caroline C. Garliss, Laurene S. Cheung, Dilshad Choudhury, Jiajia Zhang, Luis Aparicio, Sadhana Bom, Rufiaat Rashid, Justina X. Caushi, Emily Han-Chung Hsiue, Katherine Cascino, Elizabeth A. Thompson, Source Type: research
Allergic Response to Medical Products in Patients with Alpha-gal Syndrome
Galactose- α-1,3-galactose (α-gal) is a carbohydrate that is ubiquitously expressed in all mammals except for primates and humans. Patients can become sensitized to this antigen and develop α-gal syndrome (AGS), or a red meat allergy. Symptoms range from generalized gastroenteritis and malaise to anaphylaxi s, and in endemic areas, the prevalence can be as high as 20%. While AGS patients commonly avoid α-gal by avoiding meat, patients have also developed symptoms due to animal-derived medical products and devices.
Source: The Journal of Thoracic and Cardiovascular Surgery - April 8, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Kasinath V. Kuravi, Lori T. Sorrells, Joseph R. Nellis, Farzana Rahman, Anneke H. Walters, Robert G. Matheny, Shailesh K. Choudhary, David L. Ayares, Scott P. Commins, John R. Bianchi, Joseph W. Turek Source Type: research
Fetomaternal immune cross talk modifies T-cell priming through sustained changes to DC function
Prenatal exposure to infections can modify immune development. These environmental disturbances during early life potentially alter the incidence of inflammatory disorders as well as priming of immune responses. Infection with the helminth Schistosoma mansoni is widely studied for its ability to alter immune responsiveness and is associated with variations in coinfection, allergy, and vaccine efficacy in endemic populations.
Source: Journal of Allergy and Clinical Immunology - March 5, 2021 Category: Allergy & Immunology Authors: Matthew Lacorcia, Sonakshi Bhattacharjee, Kristina Laubhahn, Fahd Alhamdan, Marija Ram, Andreas Muschaweckh, Daniel P. Potaczek, Anna Kosinska, Holger Garn, Ulrike Protzer, Harald Renz, Clarissa Prazeres da Costa Source Type: research
Microbiological profile in chronic granulomatous disease patients in a single Brazilian primary immunodeficiency center
CONCLUSION: Staphylococcus sp., Staphylococcus aureus, and Aspergillus sp. were the most frequent agents found in this cohort. M. tuberculosis should be considered in endemic area. Detection of infectious agents drives to the adequate treatment and benefits the evolution of patients with CGD.PMID:33641311 | DOI:10.15586/aei.v49i2.82
Source: Allergologia et Immunopathologia - February 28, 2021 Category: Allergy & Immunology Authors: Aim ée Filippini Bifulco Oliveira Antonio Carlos Pastorino Mayra de Barros Dorna Ana Paula Beltran Moschione Castro Jos é Roberto Mendes Pegler Beni Morgenstern Magda Maria Sales Carneiro-Sampaio Source Type: research
