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Doctors have long considered the thymus expendable. But could removing it be fatal?
The thymus, a butterfly-shaped organ that sits between our collarbones, has never seemed like a particularly useful appendage—at least in adults. During early childhood, it provides a place for T cells (the T stands for thymus) to mature into immune cells that attack invaders. But during adolescence the organ begins to shrink and mostly stops producing these cells. By adulthood, it’s assumed to be so useless that cardiac surgeons will occasionally remove it just to get easier access to the heart.
But researchers have recently started to question that assumption, and a study published today in
The New England Jo...
Source: ScienceNOW - August 2, 2023 Category: Science Source Type: news
The Conspirituality of Robert F. Kennedy Jr.
This article has been adapted from Chapter 23 of Conspirituality: How New Age Conspiracy Theories Became a Health Threat by Derek Beres, Matthew Remski, and Julian Walker. Copyright © 2023. Available from PublicAffairs, an imprint of Hachette Book Group, Inc.
Source: TIME: Health - July 5, 2023 Category: Consumer Health News Authors: Derek Beres, Matthew Remski, and Julian Walker Tags: Uncategorized freelance politics Source Type: news
Lipid nanoparticles technology in vaccines: Shaping the future of prophylactic medicine
Colloids Surf B Biointerfaces. 2022 Dec 20;222:113111. doi: 10.1016/j.colsurfb.2022.113111. Online ahead of print.ABSTRACTThroughout decades, the intrinsic power of the immune system to fight pathogens has inspired researchers to develop techniques that enable the prevention or treatment of infections via boosting the immune response against the target pathogens, which has led to the evolution of vaccines. The recruitment of Lipid nanoparticles (LNPs) as either vaccine delivery platforms or immunogenic modalities has witnessed a breakthrough recently, which has been crowned with the development of effective LNPs-based vacc...
Source: Colloids and Surfaces - December 31, 2022 Category: Biotechnology Authors: Ahmed A H Abdellatif Mahmoud A Younis Abdullah F Alsowinea Emad M Abdallah Mohamed S Abdel-Bakky Amal Al-Subaiyel Yasser A H Hassan Hesham M Tawfeek Source Type: research
Be Prepared For The Next Pandemic
Whether pro-vaccine or anti-vaccine, you’re not getting the complete Covid picture. That’s why it’s so important that you take steps to protect yourself.
When it comes to this virus, the truth is a moving target. This is partly because the virus is evolving but mostly because we just don’t have the data we need to make a truly informed decision.
And here’s one narrative no one is talking about…
Studies show that chemicals commonly found in food and consumer products weaken your immune system and make the symptoms of Covid worse — especially among those who are already vulnerable.1
You see, these toxins in...
Source: Al Sears, MD Natural Remedies - December 23, 2022 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news
Keep The Flu Away In A Time Of “ Twindemics ”
Flu season is here, and the CDC has shifted into overdrive…pushing you to get your flu vaccine as soon as possible.
Once again, they’re insisting it’s more important than ever because of Covid.
Flu shots have an unquestioned reputation. The message from the medical establishment is that you need to ignore any vaccines’ potential adverse effects.
But that doesn’t mean they don’t exist…
In a moment, I’ll show you ways to bolster your native immunity so you can enjoy optimal health year-round. But first, for my new readers, let me tell you why I’ll never get a flu shot.
Unlike some of my colleagues i...
Source: Al Sears, MD Natural Remedies - December 23, 2022 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Health Source Type: news
How to Tell If Your Health Concerns Are Normal —Or a Sign of Something More
Is that sniffle a sign of seasonal allergies or COVID-19? It’s a question you’ve likely asked yourself at least once—and perhaps lots of times—over the last few years.
Especially during a pandemic, it’s normal to analyze your health. But for some people, those thoughts can cross a line into more problematic territory. At least 4% of the U.S. population lives with what’s known as health anxiety, or an excessive preoccupation with health and illness—and symptoms of the condition may have emerged or worsened for certain people during these virus-dominated recent years, experts say.
[t...
Source: TIME: Health - September 20, 2022 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthscienceclimate Mental Health Source Type: news
Vaccines against SARS ‐CoV‐2 are safe to administer in patients with antibodies to pegaspargase
ConclusionSARS-CoV-2 vaccination is safe in this population.
Source: Cancer Medicine - July 15, 2022 Category: Cancer & Oncology Authors: Hope D. Swanson,
Hana Hakim,
Diego R. Hijano,
Ted Morton,
Shane Cross,
Hiroto Inaba,
Sima Jeha,
Ching ‐Hon Pui,
Seth E. Karol Tags: BRIEF COMMUNICATION Source Type: research
Myeloid-Derived Suppressor Cells: The Expanding World of Helminth Modulation of the Immune System
Infection with helminths or parasitic worms are highly prevalent worldwide especially in developing regions. Helminths cause chronic infections that are associated with suppression of immune responses to unrelated pathogens, vaccines, and by-stander antigens responsible for dysregulated immune responses as occurs in diseases such as allergies. Helminths use multiple mechanisms to modulate the immune system to evade the highly polarized type 2 immune response required to expel adult worms and for immunity to reinfection. Anthelmintic drugs are efficient in reducing adult worm burdens in helminth-infected individuals, but re...
Source: Frontiers in Immunology - June 10, 2022 Category: Allergy & Immunology Source Type: research
What Are Some Indications for Using Dexamethasone?
Discussion
Corticosteroids are a group of drugs which can be naturally or synthetically produced. Naturally occurring substances are produced in the adrenal gland, and are protein-bound (primarily corticosteroid-binding globulin and albumin). In the target tissues, they may need to be converted to an active substance. They are then reduced, oxidized, hydroxylated or conjugated as measures to inactivate them. Synthetic steroids have less protein binding and depending on their structure are more or less resistant to inactivation. Prednisone is the glucocorticoid most often used for treatment, especially as it has a short hal...
Source: PediatricEducation.org - June 7, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
CTL ELISPOT Assay and T Cell Detection
Methods Mol Biol. 2021;2325:65-77. doi: 10.1007/978-1-0716-1507-2_5.ABSTRACTEnzyme-linked immune absorbent spot (Elispot) is a quantitative method for measuring relevant parameters of T-cell activation. The sensitivity of Elispot allows the detection of low-frequency antigen-specific T-cells that secrete cytokines and effector molecules, such as granzyme B and perforin. Cytotoxic T-cell (CTL) studies have taken advantage with this high-throughput technology by providing insights of quantity and immune kinetics. Accuracy, sensitivity, reproducibility, and robustness of Elispot resulted in a wide range of applications in res...
Source: Mol Biol Cell - May 30, 2021 Category: Molecular Biology Authors: Elena Ranieri Giuseppe Stefano Netti Margherita Gigante Source Type: research
COVID-19 vaccination in mastocytosis: recommendations of the European Competence Network on Mastocytosis (ECNM) and American Initiative in Mast Cell Diseases (AIM)
J Allergy Clin Immunol Pract. 2021 Apr 5:S2213-2198(21)00386-X. doi: 10.1016/j.jaip.2021.03.041. Online ahead of print.ABSTRACTMastocytosis is a neoplasm characterized by an accumulation of mast cells in various organs and increased risk for severe anaphylaxis in patients with concomitant allergies. Covid-19 is a pandemic that is associated with a relatively high rate of severe lung disease and mortality. The mortality is particularly high in those with certain comorbidities and increases with age. Recently, several companies have developed an effective vaccination against Covid-19. Although the reported frequency of sever...
Source: Clinical Lung Cancer - April 8, 2021 Category: Cancer & Oncology Authors: Patrizia Bonadonna Knut Brockow Marek Niedoszytko Hanneke Oude Elberink Cem Akin Boguslaw Nedoszytko Joseph H Butterfield Ivan Alvarez-Twose Karl Sotlar Juliana Schwaab Mohamad Jawhar Mariana Castells Wolfgang R Sperr Olivier Hermine Jason Gotlib Roberta Source Type: research
Johnson & Johnson Announces U.S. CDC Advisory Committee Recommends First Single-Shot COVID-19 Vaccine for Adults 18 and Older in U.S.
NEW BRUNSWICK, N.J., February 28, 2021 – Johnson & Johnson (NYSE: JNJ) (the Company) today announced that the U.S. Centers for Disease Control and Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP) has recommended the first single-shot COVID-19 vaccine, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson, for individuals 18 years of age and older under the Emergency Use Authorization (EUA) issued by the U.S. Food and Drug Administration (FDA). “For more than 130 years, Johnson & Johnson has come to the aid of people during times of crisis, and we believe today’s re...
Source: Johnson and Johnson - February 28, 2021 Category: Pharmaceuticals Source Type: news
