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Total 53 results found since Jan 2013.
A prospective randomized trial comparing patent blue and methylene blue for the detection of the sentinel lymph node in breast cancer patients
Conclusion: Methylene blue performed as well as patent blue in identifying the SLN in breast cancer patients.Resumo Introdu ção: O azul de metileno é mais facilmente encontrado para comercialização e a um preço menor que o azul patente. Parece ainda haver menor risco de anafilaxia. Objetivo: Comparar a taxa de detecção do linfonodo sentinela com o azul patente e com o azul de metileno. Método: Foram incluídas , de forma randomizada e prospectiva, 142 pacientes com diagnóstico de carcinoma mamário invasor, que consentiram em participar livremente do estudo. Foram injetados 2 mL de azul patente (grupo A) em 69 (4...
Source: Revista da Associacao Medica Brasileira - March 24, 2017 Category: Journals (General) Source Type: research
Phaleria macrocarpa (Boerl.) Fruit induce G0/G1 and G2/M cell cycle arrest and apoptosis through mitochondria-mediated pathway in MDA-MB-231 Human Breast Cancer Cell
Conclusion The results indicated that PMEAF treatment induced apoptosis in MDA-MB-231 cells through intrinsic mitochondrial related pathway with the participation of pro and anti-apoptotic proteins, caspases, G0/G1 and G2/M-phases cell cycle arrest by p53-mediated mechanism. Graphical abstract
Source: Journal of Ethnopharmacology - March 1, 2017 Category: Drugs & Pharmacology Source Type: research
Dr. Elizabeth Boham on Breast Cancer, Women's Wellness and Becoming the CEO of Your Health
I am so excited to share a recent interview that I did with Dr. Elizabeth Boham, my dear friend and long-time colleague here at The UltraWellness Center in Lenox, Massachusetts. She is Board Certified in Family Medicine from Albany Medical School and an Institute for Functional Medicine Certified Practitioner. She also has her undergraduate degree in nutritional biochemistry from Cornell University and her graduate degree and Registered Dietitian from Columbia University.Dr. Boham joined my team in 2007. What is so interesting about her journey is that she knows first-hand how difficult it can be to navigate through the ...
Source: Healthy Living - The Huffington Post - January 3, 2017 Category: Consumer Health News Source Type: news
Mother ’s Milk and the Environment: Might Chemical Exposures Impair Lactation?
New mothers who quit breastfeeding earlier than they had wanted often chalk it up to not being able to produce enough milk. But a handful of researchers are exploring whether certain environmental exposures may affect some women’s ability to lactate.© Tony Anderson/Getty Images
Lactation support includes teaching women techniques to breastfeed and build their milk supply, as well as reassuring them of their ability to nourish their infants.© Phanie/Alamy Stock Photo
Education and counseling have been important tools in boosting breastfeeding rates, after decades of marketing mess...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: News Focus January 2017 Source Type: research
Abstract IA03: Genetic and non-genetic risk factors of pancreatic cancer
In the United States, incidence and mortality rates of pancreatic cancer (PC) have remained largely unchanged since 1973. During 2005-2009, the incidence rate for Whites was 11.6/105 and for African-Americans, 15.2/105. Mortality rates were 10.7/105 for Whites and 13.8/105 for African-Americans. The 5-year survival has been 4-7% for decades. The absolute number of new cases and deaths due to PC has been increasing steadily since 2004 due to the baby-boomer generation reaching the risk window (where median age at diagnosis is 71 years). By 2030, PC will be the second most common cause of cancer mortality, after lung cancer....
Source: Cancer Research - December 13, 2016 Category: Cancer & Oncology Authors: Gloria M. Petersen Tags: Epidemiology and Risk Factors Source Type: research
Antiproliferative Effect of Synadenium grantii Hook f. stems (Euphorbiaceae) and a Rare Phorbol Diterpene Ester
Synadenium grantii is frequently used for the treatment of various diseases such as allergies, gastric disorders, and especially cancer. The aim of this study was to evaluate the possible antiproliferative potential of the methanol extract, fractions, and pure compounds from the stems of S grantii. Phytochemical analysis was carried out by conventional chromatographic techniques, and the antiproliferative activity was analyzed using the sulforhodamine B assay and an MTT-based assay. Nonpolar fraction and its subfractions from the stems of S grantii exhibited promising cytostatic effect against several human tumor cell line...
Source: International Journal of Toxicology - December 1, 2016 Category: Toxicology Authors: Campos, A., Vendramini-Costa, D. B., Longato, G. B., Zermiani, T., Ruiz, A. L. T. G., de Carvalho, J. E., Pandiella, A., Cechinel Filho, V. Tags: Regular Articles Source Type: research
5 Things Wrong With Your Deodorant
You wouldn’t swallow a spoonful of toxic cosmetic ingredients. But in some ways, smearing them under your arms in the form of deodorant or antiperspirant may be worse.
“When you eat something, it’s broken down by your liver and digestive system,” says Heather Patisaul, Ph.D., an associate professor of biology at North Carolina State University. “But when you put something on your skin, there are times when it can enter your bloodstream without being metabolized.”
Patisaul spends most of her time studying known and potential endocrine disruptors—chemicals that may mess with the func...
Source: TIME.com: Top Science and Health Stories - July 5, 2016 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized antiperspirant beauty beauty products deodorant Environment natural deodorant Toxic toxins Source Type: news
EPMA-World Congress 2015
Table of contents
A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma
Jella-Andrea Abraham, Olga Golubnitschaja
A2 Integrated market access approach amplifying value of “Rx-CDx”
Ildar Akhmetov
A3 Disaster response: an opportunity to improve global healthcare
Russell J. Andrews, Leonidas Quintana
A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy
Russell J. Andrews
A5 The role of ...
Source: EPMA Journal - May 8, 2016 Category: Global & Universal Source Type: research
Paricalcitol attenuates lipopolysaccharide-induced myocardial inflammation by regulating the NF-κB signaling pathway.
Abstract
Vitamin D deficiency is associated with an increased risk of cardiovascular disease, diabetes, colon and breast cancer, infectious diseases and allergies. Vascular alterations are an important pathophysiological mechanism of sepsis. Experimental data suggest that paricalcitol, a vitamin D2 analogue, exerts beneficial effects on renal inflammation and fibrosis. In the present study, we aimed to investigate the effects of paricalcitol on lipopolysaccharide (LPS)-induced myocardial inflammation and to elucidate the underlying mechanisms. We used primary cultured human umbilical vein endothelial cells for...
Source: International Journal of Molecular Medicine - March 4, 2016 Category: Molecular Biology Authors: Lee AS, Jung YJ, Thanh TN, Lee S, Kim W, Kang KP, Park SK Tags: Int J Mol Med Source Type: research
Abstract P2-12-02: Axillary reverse mapping: A feasibility study
ConclusionThe identification rate of ARM lymphatics and nodes is low when only blue dye is used. The method appears it to be oncologically safe in patients with low tumour burden. However there is need for further studies will before this procedure can be universally applied without compromising the oncologic safety.Once the technique is proven to be oncologically safe even in a selected group of patients, a large randomized trial will be needed to give a satisfactory answer whether the problem of lymphedema be eliminated or minimized in the patients in whom arm lymphatics are successfully preserved.Citation Format: Khare ...
Source: Cancer Research - February 18, 2016 Category: Cancer & Oncology Authors: Khare, S., Singh, G., Das, A., Bal, A. Tags: Poster Session Abstracts Source Type: research
Comparison of Doctors' and Breast Cancer Patients' Perceptions of Docetaxel, Epirubicin, and Cyclophosphamide (TEC) Toxicity
Abstract
In Spain, around 26,000 cases of breast cancer are diagnosed each year, representing nearly 30% of all cancers in women. The aim this study was to compare the perceptions of nonhematologic toxicities after administration of a docetaxel, epirubicin, and cyclophosphamide (TEC) regimen between breast cancer patients and oncologists. Furthermore, the relationship between such adverse events and quality of life (QOL) was evaluated. Cross‐sectional study carried out among 92 breast cancer patients who received TEC as neoadjuvant or adjuvant treatment. The main nonhematologic toxicities experienced by breast cancer pat...
Source: The Breast Journal - February 11, 2016 Category: Cancer & Oncology Authors: Juan Bayo, Blanca Prieto, Francisco Rivera Tags: Original Article Source Type: research
More than Cosmetic Changes: Taking Stock of Personal Care Product Safety
Joe Greco, principal scientist in beauty care product development for Johnson & Johnson, works on reformulating an acne gel cleanser. Johnson & Johnson is one of several companies investing considerable resources to remove specific chemicals from their products.© Rebecca Kessler
An infographic prepared by the PCPC lays out the order of events and estimated timeframe for reformulating products.© Personal Care Products Council
In 2013 Johnson & Johnson completed reformulation of about 100 baby products, a process that involved approximately 1,500 prototypes. Some prototyp...
Source: EHP Research - May 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Allergies and Policy Chemical Sensitivities Chemical Testing Children's Health Endocrine Disruptors Health Disparities Industry Issues Laws May 2015 Organic Farming and Products Personal Care Products Regu Source Type: research
Abstract P2-01-15: Noninvasive assessment of axillary lymph node metastases in breast cancer using EpCAM antibody
Conclusion:The NIR dye labeled EpCAM antibody (anti-EpCAM/Cy7) has a high accuracy in evaluating the axillary lymph node status of breast cancer in the animal experiment. Our tiny preclinical experiment showed the value of using EpCAM antibody as a new method for noninvasive lymph node evaluation for breast cancer and potentially extended in a lot of other epithelial originated cancers.
Citation Format: Shu Wang, Jiajia Guo, Liulu Zhang, Houpu Yang. Noninvasive assessment of axillary lymph node metastases in breast cancer using EpCAM antibody [abstract]. In: Proceedings of the Thirty-Seventh Annual CTRC-AACR San Antonio Br...
Source: Cancer Research - April 30, 2015 Category: Cancer & Oncology Authors: Wang, S., Guo, J., Zhang, L., Yang, H. Tags: Poster Session Abstracts Source Type: research
Abstract P6-08-39: Influence of lifestyle factors and tumor cell dissemination in 632 early breast cancer patients
Conclusion: Lifestyle factors seems to influence the outcome in our cohort of EBC patients as shown in previous studies. Final data and results regarding to tumor cell dissemination compared to lifestyle behaviour will be available for the SABCS 2014.
Citation Format: Bahriye Aktas, Anna Frackenpohl, Siegfried Hauch, Johann Kraus, Hans Armin Kestler, Rainer Klaus Kimmig, Sabine Kasimir-Bauer. Influence of lifestyle factors and tumor cell dissemination in 632 early breast cancer patients [abstract]. In: Proceedings of the Thirty-Seventh Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2014 Dec 9-13; San Antonio, TX. Ph...
Source: Cancer Research - April 30, 2015 Category: Cancer & Oncology Authors: Aktas, B., Frackenpohl, A., Hauch, S., Kraus, J., Kestler, H. A., Kimmig, R. K., Kasimir-Bauer, S. Tags: Poster Session Abstracts Source Type: research
The incredible dogs that are being trained to detect cancer
For people with life-threatening conditions such as diabetes, Medical Detection Dogs can be invaluable. Chosen by the Telegraph for this year's Christmas appeal, the charity is even training clever hounds to sniff out cancer
Source: Telegraph Health - December 8, 2014 Category: Consumer Health News Tags: allergies telegraph charity medical detection dogs cancer research breast cancer diabetes telegraph christmas charity appeal 2014 Source Type: news
