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Mammographic density and associated predictive factors for Chinese women
(Source: The Breast Journal)
Source: The Breast Journal - November 27, 2017 Category: Cancer & Oncology Authors: Tong Li, Jing Li, Min Dai, Jiansong Ren, Hongzhao Zhang, Zihan Mi, Rob Heard, Claudia Mello ‐Thoms, Jie He, Patrick Brennan Tags: COMMENTARY Source Type: research

Single dose systemic acetaminophen to improve patient reported quality of recovery after ambulatory segmental mastectomy: A prospective, randomized, double ‐blinded, placebo controlled, clinical trial
Abstract Few systemic drug interventions are efficacious to improve patient reported quality of recovery after ambulatory surgery. We aimed to evaluate whether a single dose systemic acetaminophen improve quality of recovery in female patients undergoing ambulatory breast surgery. We hypothesized that patients receiving a single dose systemic acetaminophen at the end of the surgical procedure would have a better global quality of postsurgical recovery compared to the ones receiving saline. The study was a prospective randomized double blinded, placebo controlled, clinical trial. Healthy female subjects were randomized to r...
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Gildasio S. Oliveira, Meghan E. Rodes, Jane Bialek, Mark C. Kendall, Robert J. McCarthy Tags: ORIGINAL ARTICLE Source Type: research

Breast abscess after intravenous methamphetamine injection into the breast
We present a case of a young female who injected methamphetamine into her mammary vein, resulting in the formation of a breast abscess. This case demonstrates a rare but dangerous complication of intravenous drug use and a possible differential diagnosis in a patient presenting with a breast abscess. (Source: The Breast Journal)
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Amanda Kistler, Nicolas Ajkay Tags: CASE REPORT Source Type: research

Large pseudoangiomatous stromal hyperplasia of the breast in adolescent patient
(Source: The Breast Journal)
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Treskova Inka, Vicari Pavel, Karnos Vaclav, Ruzicka Lukas, Mukensnabl Petr, Slunecko Robert, Kydlicek Tomas Tags: BREAST IMAGES Source Type: research

Rare occurrence of EGFR exon 19 deletion in invasive lobular carcinoma of the breast
(Source: The Breast Journal)
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Neda A. Moatamed, Matthew DeNicola, Phillipp Nham, Ryan T. Phan Tags: COMMENTARY Source Type: research

Metaplastic spindle cell carcinoma of the breast in a patient with neurofibromatosis type 1
We report a unique case of a 67‐year‐old woman with neurofibromatosis type 1, who was also diagnosed with metaplastic spindle cell carcinoma of the left breast. She had many neurofibromatosis lesions on her body, as well as the mass in the left breast. After the breast mass was diagnosed as a malignant mesenchymal tumor by core needle biopsy, the patient underwent left modified radical mastectomy. Subsequently, the pathological analysis of the tumor showed it to be a metaplastic spindle cell carcinoma. The co‐occurrence of neurofibromatosis type 1 and breast cancer, in particular metaplastic spindle cell carcinoma, i...
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Han Shin Lee, Eun Jung Jung, Ju Yeon Kim, Eun Jin Song, Chi Young Jeong, Young Tae Ju, Young Joon Lee, Soon Chan Hong, Bo Hwa Choi, Hyang Im Lee Tags: CASE REPORT Source Type: research

Nipple ‐sparing mastectomy as treatment for patients with ductal carcinoma in situ: A 10‐year follow‐up study
The objective was to determine the 10‐year oncological safety of nipple‐sparing mastectomy (NSM) in patients diagnosed with ductal carcinoma in situ (DCIS). The use of NSM preserves the nipple‐areola complex (NAC). As residual fibroglandular breast tissue can remain behind the spared NAC, its use for patient with breast cancer is controversial. The oncologic outcomes and complication rates after performing NSM compared to other techniques are still under debate and a concern when treating patients with breast cancer. We retrospectively reviewed 69 consecutive NSM patients diagnosed with DCIS during 1984‐2016 at the...
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: V íctor Lago, Vincenzo Maisto, Julia Gimenez‐Climent, Jose Vila, Carlos Vazquez, Rafael Estevan Tags: ORIGINAL ARTICLE Source Type: research

Iatrogenic Arteriovenous Fistula of the breast following core ‐biopsy presenting in pregnancy
Abstract Core‐biopsy of the breast is the standard of care for assessment of breast lumps. It is rarely associated with a vascular injury resulting in the formation of an arteriovenous fistula. Though previously noted in the medical literature, it has never been reported in the context of pregnancy and lactation. (Source: The Breast Journal)
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Sarah Barker, Michael Ashcroft, Nick Abbott Tags: CASE REPORT Source Type: research

Breast density in screening mammography in Indian population ‐ Is it different from western population?
This study evaluates the breast density in Indian population and its relationship with the age. We reviewed of all screening mammography examinations performed from May 2012 to January 2015 at our institute PGIMER, Chandigarh, INDIA. Descriptive analyses were used to examine the association between age and breast density. A total of 6132 screening mammograms were performed. Each subgroup categorized by decade of age. There was a significant inverse relationship between age and breast density (P 
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Tulika Singh, Niranjan Khandelwal, Veenu Singla, Dileep Kumar, Madhu Gupta, Gurpreet Singh, Amanjit Bal Tags: SHORT COMMUNICATION Source Type: research

Breast cancer in young women aged 35 and under: Patterns of care and outcome
(Source: The Breast Journal)
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Maria Passhak, Shlomit Strulov Shachar, Gil Bar ‐Sela, Georgeta Fried Tags: COMMENTARY Source Type: research

Bilateral synchronous breast malignant phyllodes in a pregnant woman
(Source: The Breast Journal)
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Fernando Hernanz, M ónica González‐Noriega, Bárbara Arozamena, Jon Solano, Julia García Tags: BREAST IMAGES Source Type: research

Metastatic giant malignant phyllodes tumor of the breast
(Source: The Breast Journal)
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Alejandro Martin Sanchez, Gianluca Franceschini, Danilo Di Giorgio, Riccardo Masetti Tags: BREAST IMAGES Source Type: research

Breast education for schoolgirls; why, what, when, and how?
Abstract Schools are fundamental settings for health education and adolescent females are an important group for promoting positive breast habits. We surveyed 2089 schoolgirls (11‐18 years) to provide evidence for, and guidance on, breast education for schoolgirls. 26% reported negative feelings about their breasts and 87% reported ≥ one breast concern. 72% wanted to know more about breast cancer (69% rating this extremely important).>50% wanted to know more about breast sag and breast pain. Preferred delivery format was age eleven (50%), girls only taught sessions (41%) with female teachers (43%). A need for breas...
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Nicola Brown, Jenny Smith, Amanda Brasher, Debbie Risius, Anna Marczyk, Joanna Wakefield ‐Scurr Tags: SHORT COMMUNICATION Source Type: research

Breast radiology malpractice suits: Characteristics of frequency and outcomes ‐ national and statewide distinctions
Abstract The purpose of this study was to determine the frequency and outcomes of breast malpractice suits among all enrollees in One Call Medical Inc.'s panel of interpreting radiologists nationally and to evaluate state‐by‐state variations. The 8401 radiologists enrolled had 4764 suits, of which 826 were related to breast disease. In New York and New Jersey, the ratio of breast suits to One Call Radiologists was 0.28 and 0.27, twice as much as in any other state. Breast suits in radiology have a wide variation in frequency across the country with New York and New Jersey far exceeding all others in relative frequency ...
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Stephen R. Baker, Sri Ram Pentakota, Basil Hubbi Tags: SHORT COMMUNICATION Source Type: research

Total duct excision through a linear radial areola incision
(Source: The Breast Journal)
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Benjamin G. Baker, Vinod Mathen, James R. Harvey Tags: COMMENTARY Source Type: research

Beyond sarcopenia: Characterization and integration of skeletal muscle quantity and radiodensity in a curable breast cancer population
This study characterizes and examines age‐related changes in body composition of adults with early breast cancer and describes the creation of a novel integrated muscle measure. Female patients diagnosed with stage I‐III breast cancer with abdominal computerized tomography (CT) scans within 12 weeks from diagnosis were identified from local tumor registry (N = 241). Skeletal muscle index (muscle area per height [cm2/m2]), skeletal muscle density, and subcutaneous and visceral adipose tissue areas, were determined from CT L3 lumbar segments. We calculated a novel integrated skeletal measure, skeletal musc...
Source: The Breast Journal - November 15, 2017 Category: Cancer & Oncology Authors: Marc S. Weinberg, Shlomit S. Shachar, Hyman B. Muss, Allison M. Deal, Karteek Popuri, Hyeon Yu, Kirsten A. Nyrop, Shani M. Alston, Grant R. Williams Tags: ORIGINAL ARTICLE Source Type: research

Triple ‐negative breast cancer in the elderly
(Source: The Breast Journal)
Source: The Breast Journal - November 7, 2017 Category: Cancer & Oncology Authors: Elena Shagisultanova, Jose Mayordomo, Anthony D. Elias Tags: EDITORIAL Source Type: research

Issue Information ‐ Editorial
(Source: The Breast Journal)
Source: The Breast Journal - November 7, 2017 Category: Cancer & Oncology Tags: Issue Information Source Type: research

Intra ‐operative radiotherapy management for breast cancer treatment in patients with pseudoxanthoma elasticum: A case report
Abstract Pseudoxanthoma elasticum is a systemic metabolic disease presenting calcifications and progressive fragmentation of elastic fibers. Actually, no targeted therapies are available for the treatment; only prevention of complications is possible. Classically, pseudoxanthoma elasticum is a “benign” disease, without cancer association. Herein, we reported a singular association of pseudoxanthoma elasticum with breast carcinoma, describing the clinical management, in particular intra‐operative treatment, focusing on intra‐operative radiotherapy since no specific guidelines are available in literature. (So...
Source: The Breast Journal - November 5, 2017 Category: Cancer & Oncology Authors: Carmela Salerno, Anna Rita Vento, Maria Giacchino, Germana Lissidini, Viviana Galimberti, Giovanni Corso Tags: CASE REPORT Source Type: research

The post ‐mastectomy pain syndrome—A systematic review of the treatment modalities
(Source: The Breast Journal)
Source: The Breast Journal - November 5, 2017 Category: Cancer & Oncology Authors: Fabio Caviggioli, Francesco Klinger, Andrea Lisa, Andrea Rimondo, Luca Maione, Valeriano Vinci, Marco Klinger Tags: LETTER TO THE EDITOR Source Type: research

MRI ‐guided preoperative 125I seed localizations: Case report
Abstract Preoperative nonwire localizations with 125I seeds are performed using mammographic or ultrasonographic guidance. Current MRI‐guided interventions in the breast are primarily limited to biopsies and wire localizations. Occasionally, nonwire localization with 125I seeds is preferred, but the target is only well seen on MRI. This case report describes how MRI‐guided preoperative two 125I seed bracket localization was performed. (Source: The Breast Journal)
Source: The Breast Journal - November 5, 2017 Category: Cancer & Oncology Authors: Christine Lee Tags: CASE REPORT Source Type: research

Patient preferences for breast biopsy result notification
(Source: The Breast Journal)
Source: The Breast Journal - November 5, 2017 Category: Cancer & Oncology Authors: Hilary A. Brazeal, Susan O. Holley, Catherine M. Appleton, Michelle V. Lee Tags: COMMENTARY Source Type: research

Does the use of pretreatment MRI change the management of patients with newly diagnosed breast cancer?
This study is a retrospective chart review of all newly diagnosed breast cancer patients who underwent preoperative breast MRI at our institution between January 1, 2004 and December 31, 2009. 1352 patients comprised the study population. 241 (17.8%) patients underwent a change in surgical management as a result of preoperative MRI. Patients with tumors in the lower inner quadrant and the central breast and those with pathology of invasive lobular carcinoma were significantly more likely to have their management changed by preoperative MRI. There was also a significant trend for larger tumors to be associated with a change...
Source: The Breast Journal - November 5, 2017 Category: Cancer & Oncology Authors: James Hlubocky, Sharukh Bhavnagri, Ann Swinford, Carol Mitri, Murray Rebner, Vidya Pai Tags: ORIGINAL ARTICLE Source Type: research

Mammographic density and other risk factors for breast cancer among women in China
(Source: The Breast Journal)
Source: The Breast Journal - November 1, 2017 Category: Cancer & Oncology Authors: Tong Li, Lichen Tang, Ziba Gandomkar, Rob Heard, Claudia Mello ‐Thoms, Zhimin Shao, Patrick Brennan Tags: COMMENTARY Source Type: research

Rapidly enlarging breast mass in the setting of silicone injection augmentation mammoplasty
(Source: The Breast Journal)
Source: The Breast Journal - November 1, 2017 Category: Cancer & Oncology Authors: Sydney Thayer, Ryan Rockhill, Tawakalitu Oseni Tags: BREAST IMAGES Source Type: research

MR imaging appearance of noncalcified and calcified DCIS
Abstract To evaluate the MR appearance of noncalcified ductal carcinoma in situ (DCIS), with comparison to calcified DCIS. A retrospective, IRB‐approved review of all DCIS diagnosed via MR biopsy between 2007 and 2011 was performed. DCIS was categorized as noncalcified based on the absence of calcifications on mammography and specimen radiography. MR morphology (focus, mass, nonmass enhancement [NME]) and enhancement kinetics (initial and delayed) for noncalcified DCIS were recorded and compared based on nuclear grade (1‐3), size (5 cm), and presence of necrosis. Imaging features of noncalcified and calcified...
Source: The Breast Journal - November 1, 2017 Category: Cancer & Oncology Authors: Andrew Scott ‐Moncrieff, Megan E. Sullivan, Ellen B. Mendelson, Lilian Wang Tags: ORIGINAL ARTICLE Source Type: research

Reducing chronic breast cancer ‐related lymphedema utilizing a program of prospective surveillance with bioimpedance spectroscopy
Abstract This single‐institution experience evaluated the use of bioimpedance spectroscopy to facilitate early detection and treatment of breast cancer‐related lymphedema (BCRL) in a cohort of 596 patients (79.6% high risk). Seventy‐three patients (12%) developed an elevated L‐Dex score with axillary lymph node dissection (P 
Source: The Breast Journal - October 24, 2017 Category: Cancer & Oncology Authors: Pat W. Whitworth, Andrea Cooper Tags: SHORT COMMUNICATION Source Type: research

Conditional relative survival among female breast cancer patients in the United States
(Source: The Breast Journal)
Source: The Breast Journal - October 24, 2017 Category: Cancer & Oncology Authors: Ray M. Merrill Tags: COMMENTARY Source Type: research

Cancer identified in accessory breast tissue within the mid axilla
(Source: The Breast Journal)
Source: The Breast Journal - October 24, 2017 Category: Cancer & Oncology Authors: Anne Kuritzky, Lauren Walheim, Nazanin Khakpour Tags: BREAST IMAGES Source Type: research

Ultrasound ‐guided wire localization of focal ductal dilatation in the evaluation and treatment of pathologic nipple discharge
Abstract Patients presenting with pathologic nipple discharge (PND) often pose a diagnostic and therapeutic challenge. We used ultrasound to identify focal ductal dilatation—hypothesized to be a radiographic manifestation of the causative lesion—in patients with PND and no relevant clinical or radiographic findings. Twenty‐two excisions guided by ultrasound wire localization of focal duct dilation were performed. Surgical pathology revealed papilloma in 20 cases (91%); atypia or carcinoma was detected in 7 cases (32%). The ultrasound finding of focal duct dilatation enables excision of otherwise occult though...
Source: The Breast Journal - October 24, 2017 Category: Cancer & Oncology Authors: Anya Romanoff, Benjamin Nulsen, Jolinda Mester, Shabnam Jaffer, Christina Weltz Tags: SHORT COMMUNICATION Source Type: research

Chylous leakage after axillary lymph node dissection in a patient with breast cancer
(Source: The Breast Journal)
Source: The Breast Journal - October 24, 2017 Category: Cancer & Oncology Authors: Takaaki Oba, Mayu Ono, Asumi Iesato, Toru Hanamura, Takayuki Watanabe, Tokiko Ito, Toshiharu Kanai, Kazuma Maeno, Ken ‐ichi Ito Tags: COMMENTARY Source Type: research

Micropapillary variant of mucinous breast carcinoma: A  distinct subtype
Abstract Invasive micropapillary carcinoma of the breast is a subtype with high malignant potential characterized by lymphovascular invasion (LVI) and a predilection for axillary lymph node (AXLN) metastases. In contrast, pure mucinous breast carcinoma (MBC) is relatively indolent with low metastatic potential. Recent studies have described a histologic variant of breast cancer that displays combined mucinous and micropapillary patterns, ie, micropapillary variant of mucinous carcinoma (MpVMBC). This underrecognized variant is, as yet, incompletely characterized clinicopathologically. Extant reports suggest a more aggressi...
Source: The Breast Journal - October 24, 2017 Category: Cancer & Oncology Authors: Katrina Collins, Andrew Ricci Tags: ORIGINAL ARTICLE Source Type: research

Pertuzumab and trastuzumab infusion related cytokine release syndrome in a chemotherapy naive patient with metastatic breast cancer
Abstract Pertuzumab is a monoclonal antibody that targets and down regulates HER‐2/neu expression in ductal breast tumors. Other HER‐2/neu monoclonal antibodies, particularly trastuzumab, have been implicated to induce infusion related reactions such as cytokine release syndrome (CRS). Here, we report a case of pertuzumab associated CRS prior to infusion of trastuzumab which warranted hospitalization for symptom management. (Source: The Breast Journal)
Source: The Breast Journal - October 13, 2017 Category: Cancer & Oncology Authors: Adonice Khoury, Vikas Parihar, Lillie O'steen, Kartikeya Cherabuddi Tags: CASE REPORT Source Type: research

The Intact ® breast lesion excision system as a therapeutic device for selected benign breast lesions
Abstract The aim of this paper is to evaluate our Unit's initial experience using the Intact breast lesion excision system as a therapeutic excision option for benign or borderline breast lesions, which otherwise would entail open operative excision. The study includes the first 111 patients who underwent therapeutic excision with the intact radiofrequency system between December 2012 and May 2016 performed at the Meirav Center for Breast Health, at the Chaim Sheba Medical Center, Ramat Gan Israel. The indications for the procedure included those patients who have benign, or atypical high risk lesions following a previous ...
Source: The Breast Journal - October 11, 2017 Category: Cancer & Oncology Authors: Miri Sklair ‐Levy, Shlomi Rayman, Ady Yosepovich, Andrew Zbar, David Goitein, Douglas Zippel Tags: ORIGINAL ARTICLE Source Type: research

Sentinel node biopsy in ductal carcinoma in situ of the breast: Never justified?
Abstract Sentinel lymph node biopsy for ductal carcinoma in situ (DCIS) of the breast is not standard of care. However, nodal involvement for DCIS patients is reported. Aim of our study was to identify preoperative features predictive of nodal involvement in DCIS patients. We have retrospectively reviewed 175 patients with a preoperative diagnosis of DCIS following a vacuum‐assisted breast biopsy, and undergoing surgery with sentinel node biopsy. Variables distribution was compared between patients upstaged to invasive cancer at final pathology and patients with a confirmed DCIS, and between positive vs negative sentinel...
Source: The Breast Journal - October 11, 2017 Category: Cancer & Oncology Authors: Luca Sorrentino, Alessandra Sartani, Daniela Bossi, Rosella Amadori, Manuela Nebuloni, Marta Truffi, Matteo Bonzini, Eliana Riggio, Diego Foschi, Fabio Corsi Tags: ORIGINAL ARTICLE Source Type: research

Characteristics and clinical outcomes of pleomorphic lobular carcinoma in situ of the breast
Abstract Pleomorphic lobular carcinoma in situ (PLCIS) of the breast is a rare variant of lobular carcinoma in situ (LCIS). We reviewed 78 cases of PLCIS diagnosed at our institution from 1998 to 2012. Among all cases, 47 (60%) were associated with invasive carcinoma and/or ductal carcinoma in situ (DCIS) after final surgical excision. Of the 20 cases with PLCIS alone on core needle biopsy (CNB), 6 (30%) were upgraded to invasive carcinoma or DCIS after final surgical excision. Our findings support a recommendation for complete surgical excision of PLCIS when diagnosed on CNB. (Source: The Breast Journal)
Source: The Breast Journal - September 19, 2017 Category: Cancer & Oncology Authors: Carolina E. Fasola, Jie Jane Chen, Kristin C. Jensen, Kimberly H. Allison, Kathleen C. Horst Tags: SHORT COMMUNICATION Source Type: research

Withdrawal Notice: ‘Axillary Metastatic Disease Secondary to Occult Breast Cancer: A Diagnostic and Therapeutic Dilemma’ by Lanitis, S.; Sivakumar, S.; Cathcart, P; Rice, A; Filippakis, G.; Al Mufti, R.; Hadjiminas, D.
Abstract The above Letter to the Editor, published online in Wiley Online Library as the Version of Record on 21 December 2009 (https://doi.org/10.1111/j.1524-4741.2009.00827.x) has been withdrawn by agreement between the Editor‐in‐Chief, Shahla Masood, and Wiley Periodicals, Inc. The withdrawal has been agreed to due to an oversight by the publisher that resulted in the Letter not being assigned to an Issue on a timely basis. (Source: The Breast Journal)
Source: The Breast Journal - September 15, 2017 Category: Cancer & Oncology Tags: Withdrawal Notice Source Type: research

The Predicament of the Probably Benign Breast MRI: Should We Rely on Intuition?
(Source: The Breast Journal)
Source: The Breast Journal - September 15, 2017 Category: Cancer & Oncology Authors: Amie Y. Lee, Bonnie N. Joe, Elissa R. Price Tags: Editorial Source Type: research

Issue Information ‐ Editorial
(Source: The Breast Journal)
Source: The Breast Journal - September 15, 2017 Category: Cancer & Oncology Tags: Issue Information Source Type: research

Delayed and localized pemphigus vulgaris after breast cancer radiotherapy
Abstract Breast cancer treatment involving ionizing radiation causes characteristic radiation dermatitis in the majority of patients. The DNA damaging effects of radiation can rarely predispose to primary inflammatory dermatoses, such as pemphigus vulgaris. In such cases, the disease presents with all the hallmarks of the primary dermatosis, but the eruption is limited to the field of irradiation and is often amenable to treatment. In contrast, occurrence of generalized pemphigus vulgaris in this setting may mean cancer recurrence. The mechanism by which radiotherapy induces localized disease remains unknown, but there is ...
Source: The Breast Journal - September 11, 2017 Category: Cancer & Oncology Authors: Hiu Kwan Carolyn Tang, Doreen Yin Hui Lee, Ian Thompson, John R. Ingram, Natalie Stone, Girish K. Patel Tags: CASE REPORT Source Type: research

A case of metastatic lobular carcinoma with overexpression of Trop ‐2: Implications for the consideration of novel therapeutics
(Source: The Breast Journal)
Source: The Breast Journal - September 11, 2017 Category: Cancer & Oncology Authors: Wilfrido D. Mojica, Margaret Brandwein ‐Weber, Elizabeth A. Korangy Tags: COMMENTARY Source Type: research

Comparison of HER2 status of breast cancer between Chinese women in China and Chinese ‐American women in the US
(Source: The Breast Journal)
Source: The Breast Journal - September 6, 2017 Category: Cancer & Oncology Authors: Yi ‐Ling Yang, Xiao‐Long Qian, Li Fu Tags: LETTER TO THE EDITOR Source Type: research

Polyacrylamide gel augmentation mammoplasty: Breast Images
(Source: The Breast Journal)
Source: The Breast Journal - September 6, 2017 Category: Cancer & Oncology Authors: Ebru D üşünceli Atman, Melahat Kul, Mustafa Fatih Arslan, Çağlar Uzun, Evren Üstüner Tags: BREAST IMAGES Source Type: research

Axillary lymphangioma in an asymptomatic adult female
(Source: The Breast Journal)
Source: The Breast Journal - September 6, 2017 Category: Cancer & Oncology Authors: Niketa Chotai, Elizabeth Fok, Patrick Chan, Bernard Ho Tags: BREAST IMAGES Source Type: research

Performance characteristics of digital vs film screen mammography in community practice
Abstract We compared the performance characteristics of 297 629 full field digital (FFDM) and 416 791 screen film mammograms (SFM). Sensitivity increased with age, decreased with breast density, and was lower for more aggressive and lobular tumors. While sensitivity did not differ significantly by modality, specificity was generally 1%‐2% points higher for FFDM than for SFM across age and breast density categories. The lower recall rate for FFDM vs SFM in our study may partially explain performance differences by modality. In this large health care organization, modest gains in performance were achieved with th...
Source: The Breast Journal - September 1, 2017 Category: Cancer & Oncology Authors: Firas Dabbous, Therese A. Dolecek, Sarah M. Friedewald, Katherine Y. Tossas ‐Milligan, Tere Macarol, Wm. Thomas Summerfelt, Garth H. Rauscher Tags: SHORT COMMUNICATION Source Type: research

Breast density in multiethnic women presenting for screening mammography
Abstract Data on ethnic variations in breast density are limited and often not inclusive of underrepresented minorities. As breast density is associated with elevated breast cancer risk, investigating racial and ethnic difference may elucidate the observed differences in breast cancer risk among different populations. We reviewed breast density from initial screening of women from the Capital Breast Care Center and Georgetown University Hospital from 2010 to 2014. Patient demographics including race, age at screening, education, menopausal status, and body mass index were abstracted. We recorded the BI‐RADS density categ...
Source: The Breast Journal - September 1, 2017 Category: Cancer & Oncology Authors: Bridget A. Oppong, Chiranjeev Dash, Suzanne O'Neill, Yinan Li, Kepher Makambi, Edward Pien, Erini Makariou, Tesha Coleman, Lucile L. Adams ‐Campbell Tags: ORIGINAL ARTICLE Source Type: research

Trends in oncoplastic breast surgery and breast reconstruction over the past 35  years
(Source: The Breast Journal)
Source: The Breast Journal - September 1, 2017 Category: Cancer & Oncology Authors: Ruffo Freitas ‐Junior, Sara Socorro Faria, Régis Resende Paulinelli, Edésio Martins Tags: COMMENTARY Source Type: research

Mucocele ‐like lesions diagnosed on breast core biopsy: Low risk of upgrade and subsequent carcinoma
Abstract Mucocele‐like lesions of the breast diagnosed on core biopsy are usually excised to exclude the possibility of partial sampling of an invasive mucinous carcinoma. The goal of this study was to correlate the pathologic and radiologic features of mucocele‐like lesions to determine if excision is mandatory. Over a 16 year period we identified 32 patients with mucocele‐like lesions diagnosed on 27 (84%) stereotactic and 5 (16%) ultrasound‐guided core biopsies. The indications for core biopsy were: calcifications in 24 (75%), a mass in 7 (22%), and a mass with calcifications in 1 (3%). There were 22 (69%) mucoc...
Source: The Breast Journal - September 1, 2017 Category: Cancer & Oncology Authors: Gloria Zhang, Dana Ataya, Paulette L. Lebda, Benjamin C. Calhoun Tags: ORIGINAL ARTICLE Source Type: research

Invasive breast carcinomas with ATM gene variants of uncertain significance share distinct histopathologic features
Abstract The increasing availability of next‐generation sequencing for clinical research dramatically improved our understanding of breast cancer genetics and resulted in detection of new mutation variants. Cancer risk data relating to some of these variants are insufficient, prompting the designation of variants of uncertain significance (VUS). The histopathologic characteristics of these variants have not been previously described. We propose to depict these characteristics and determine if invasive carcinomas with similar VUS genes share similar histomorphologic features. In total, 28 invasive breast cancers with VUS ...
Source: The Breast Journal - September 1, 2017 Category: Cancer & Oncology Authors: Ahmed A. Abdulrahman, Rebecca C. Heintzelman, Melanie Corbman, Fernando U. Garcia Tags: ORIGINAL ARTICLE Source Type: research

Efficacy of anthracycline/taxane ‐based neo‐adjuvant chemotherapy on triple‐negative breast cancer in BRCA1/BRCA2 mutation carriers
This study aims to estimate the pathologic complete response (pCR) rate after neo‐adjuvant chemotherapy and to compare disease‐free survival (DFS) and overall survival (OS) between pCR and non‐pCR groups of patients with triple‐negative breast cancer (TNBC) and deleterious BRCA1 or BRCA2 mutation. We carried out a retrospective analysis of 53 patients including 46 BRCA1, 6 BRCA2, and 1 combined BRCA1 and BRCA2 mutation. All patients had been diagnosed with triple‐negative breast cancer (TNBC) between 1997 and 2014. Neo‐adjuvant therapy consisted of regimens that were based on anthracycline or an anthracycline...
Source: The Breast Journal - September 1, 2017 Category: Cancer & Oncology Authors: Lucie Bignon, Jean ‐Pierre Fricker, Catherine Nogues, Emmanuelle Mouret‐Fourme, Dominique Stoppa‐Lyonnet, Olivier Caron, Alain Lortholary, Laurence Faivre, Christine Lasset, Veronique Mari, Paul Gesta, Laurence Gladieff, Akila Hamimi, Thierry Petit, Tags: ORIGINAL ARTICLE Source Type: research