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The evolution of technical prerequisites and local boundary conditions for optimization of mitral valve interventions-Emphasis on skills development and institutional risk performance
Front Cardiovasc Med. 2023 Jul 21;10:1101337. doi: 10.3389/fcvm.2023.1101337. eCollection 2023.ABSTRACTThis viewpoint report describes how the evolution of transcatheter mitral valve intervention (TMVI) is influenced by lessons learned from three evolutionary tracks: (1) the development of treatment from mitral valve surgery (MVS) to transcutaneous procedures; (2) the evolution of biomedical engineering for research and development resulting in predictable and safe clinical use; (3) the adaptation to local conditions, impact of transcatheter aortic valve replacement (TAVR) experience and creation of infrastructure for skil...
Source: Molecular Medicine - August 7, 2023 Category: Molecular Biology Authors: Riccardo Cocchieri Bertus van de Wetering Jan Baan Antoine Driessen Robert Riezebos Sjoerd van Tuijl Bas de Mol Source Type: research

Tracking emergency response actions during COVID-19 leads to development of an innovative public health evaluation tool
Can J Public Health. 2023 Aug 7. doi: 10.17269/s41997-023-00811-3. Online ahead of print.ABSTRACTSETTING: Early in the pandemic, KFL&A Public Health needed a way to capture, organize, and display COVID-19-related events to be accountable for and evaluate our actions.INTERVENTION: We used accessible software (Microsoft Office 365 suite, Microsoft PowerBI) to develop a data collection and visualization system. The Canadian Institute for Health Information (CIHI) developed a timeline and categorization approach for provincial and national COVID-related interventions, which was used to develop a regional version for local ...
Source: Canadian Journal of Public Health - August 7, 2023 Category: International Medicine & Public Health Authors: Suzanne Biro Karen Scott Emma Nagy Nancy Slipp Kinsey Beck Christina Catley Ezra Hart Source Type: research

Learning from history of natural disasters in the Sahel: a comprehensive analysis and lessons for future resilience
This study investigates the extent of damage caused by natural disasters from one of the most widely used databases-EM-DAT-with a sample size of 16 Sahelian countries over the period 1960-2020. These countries have been divided into three regions: Western Africa Sahel (WAS), Central Africa Sahel (CAS), and Eastern Africa Sahel (EAS). The analyses encompass four categories of natural hazards, namely, biological, climatological, hydrological, and meteorological. We used descriptive and test statistics to summarize the natural disaster records. Through this approach, we explore tendencies to identify the most frequently repor...
Source: Environmental Science and Pollution Research International - August 7, 2023 Category: Environmental Health Authors: Serigne Mback é Coly Malicki Zorom Babacar Leye Harouna Karambiri Aboudramane Guiro Source Type: research

Tracking emergency response actions during COVID-19 leads to development of an innovative public health evaluation tool
Can J Public Health. 2023 Aug 7. doi: 10.17269/s41997-023-00811-3. Online ahead of print.ABSTRACTSETTING: Early in the pandemic, KFL&A Public Health needed a way to capture, organize, and display COVID-19-related events to be accountable for and evaluate our actions.INTERVENTION: We used accessible software (Microsoft Office 365 suite, Microsoft PowerBI) to develop a data collection and visualization system. The Canadian Institute for Health Information (CIHI) developed a timeline and categorization approach for provincial and national COVID-related interventions, which was used to develop a regional version for local ...
Source: Canadian Journal of Public Health - August 7, 2023 Category: International Medicine & Public Health Authors: Suzanne Biro Karen Scott Emma Nagy Nancy Slipp Kinsey Beck Christina Catley Ezra Hart Source Type: research

Impact of methotrexate treatment on vaccines immunogenicity in adult rheumatological patients - Lessons learned from the COVID-19 pandemic
Biomed Pharmacother. 2023 Aug 3;165:115254. doi: 10.1016/j.biopha.2023.115254. Online ahead of print.ABSTRACTDespite the development of new biological and synthetic targeted therapies, methotrexate remains one of the most commonly used immunomodulatory drugs in rheumatology. However, its effect on the immunogenicity of vaccines has been studied only to a limited extent until recently, resulting in the lack of clear guidelines on the use of methotrexate during vaccination. Significant progress was made during the COVID-19 pandemic due to the dynamic development of research on vaccines, including patients with autoimmune inf...
Source: Herpes - August 5, 2023 Category: Infectious Diseases Authors: Jakub Wro ński Marzena Ciechomska Ewa Kuca-Warnawin Source Type: research

Ensuring access to post-cancer breast reconstructions: COVID-19 lessons from the Dutch Breast Implant Registry
CONCLUSION: Hospital-based reconstructive and gender-affirming surgery were heavily impacted during the pandemic, while private-clinic-based cosmetic surgery quickly recovered. These outcomes are useful to fuel discussions about how healthcare could be reorganized in times of capacity problems. We suggest exploring options to deploy private clinics for ambulatory surgery aiming to keep hospital capacity available for acutely ill patients.PMID:37543001 | DOI:10.1016/j.ejso.2023.106984
Source: Hand Surgery - August 5, 2023 Category: Surgery Authors: J Juli ët Vrolijk Danny A Young-Afat Marc A M Mureau Hinne A Rakhorst Annelotte C M van Bommel Marije J Hoornweg Source Type: research

Towards the CSNK2 phosphoproteome - With lessons from the COVID-19 pandemic to revealing the secrets of CSNK2 and its promise as a therapeutic target
Biochim Biophys Acta Gen Subj. 2023 Aug 3:130441. doi: 10.1016/j.bbagen.2023.130441. Online ahead of print.ABSTRACTDramatic advances in phosphoproteomics and the development of a selective chemical probe have presented new opportunities for revealing the cellular landscape of substrates for CSNK2 (formerly known as CK2 or casein kinase II). In addition to deciphering the role(s) of CSNK2 in physiology and pathophysiology, the CSNK2 phosphoproteome offers the promise of instructing the development of CSNK2-targeted therapy.PMID:37543358 | DOI:10.1016/j.bbagen.2023.130441
Source: Biochimica et Biophysica Acta - August 5, 2023 Category: Biochemistry Authors: David W Litchfield Laszlo Gyenis Daniel Menyhart Scott E Roffey Source Type: research

Impact of methotrexate treatment on vaccines immunogenicity in adult rheumatological patients - Lessons learned from the COVID-19 pandemic
Biomed Pharmacother. 2023 Aug 3;165:115254. doi: 10.1016/j.biopha.2023.115254. Online ahead of print.ABSTRACTDespite the development of new biological and synthetic targeted therapies, methotrexate remains one of the most commonly used immunomodulatory drugs in rheumatology. However, its effect on the immunogenicity of vaccines has been studied only to a limited extent until recently, resulting in the lack of clear guidelines on the use of methotrexate during vaccination. Significant progress was made during the COVID-19 pandemic due to the dynamic development of research on vaccines, including patients with autoimmune inf...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 5, 2023 Category: Drugs & Pharmacology Authors: Jakub Wro ński Marzena Ciechomska Ewa Kuca-Warnawin Source Type: research

Recall of residential history and dietary habits during pregnancy and lactation in the distant past: reliability of questionnaire-based radiation doses for persons exposed in utero and early life
This study evaluates the reliability of information obtained by standardized questionnaires used in by personal interviews for estimation of radiation thyroid doses of 1065 individuals in the Belarusian cohort of individuals who were exposed in utero and early life following the Chernobyl accident in April 1986. Data from two interviews conducted in 2012-2017 and in 2018-2022 with mothers, who were pregnant or gave birth shortly after the Chernobyl accident, were analysed. The most reliable answers dealt with various attributes related to residential history. In contrast, the reliability of answers regarding consumption ra...
Source: Radiation and Environmental Biophysics - August 4, 2023 Category: Physics Authors: Vladimir Drozdovitch Tatiana Kukhta Victor Minenko Sergey Trofimik Ilya Veyalkin Vasilina Yauseyenka Kiyohiko Mabuchi Alexander Rozhko Source Type: research