Prognostic biomarker NRG2 correlates with autophagy and epithelial ‑mesenchymal transition in breast cancer
Oncol Lett. 2024 Apr 23;27(6):277. doi: 10.3892/ol.2024.14410. eCollection 2024 Jun.ABSTRACTBreast cancer (BRCA) is a leading cause of death in women worldwide, accounting for 31% of female cancer. Autophagy plays a crucial role in cancer progression, however, the function of autophagy-related gene neuroregulatory protein 2 (NRG2) in BRCA and its underlying molecular mechanisms remain unclear. In the present study, the expression of the NRG2 gene in BRCA was significantly down-regulated compared with the normal controls. The low expression level of NRG2 was related to poor survival rate of BRCA. The receiver operating char...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Ruijie Zhou Jinjin Dai Runlong Zhou Mengyi Wang Xiaotong Deng Qing Zhuo Zhenrong Wang Fan Li Di Yao Yao Xu Source Type: research
Expression of nuclear receptor co ‑activator 7 protein is associated with poor prognosis of breast cancer
Oncol Lett. 2024 Apr 23;27(6):278. doi: 10.3892/ol.2024.14411. eCollection 2024 Jun.ABSTRACTNuclear receptor coactivator 7 (NCOA7) is an estrogen receptor binding protein. Its role in breast cancer progression has so far remained elusive. The present study aimed to determine the expression levels of NCOA7 in breast tumor samples and confirmed its potential utility as a breast cancer prognostic biomarker. The expression of NCOA7 was detected by immunohistochemical staining in 241 breast cancer tumor samples and 163 adjacent normal tissue samples. The association of NCOA7 expression with the clinicopathological characteristi...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Ziluo Peng Yanlin Li Song Xia Qian Dai Liang Yin Miao Chen Wannian Yang Genbao Shao Qiong Lin Source Type: research
Association of ADP ‑ribosylation factor family genes with prognosis and immune infiltration of breast cancer
Oncol Lett. 2024 Apr 23;27(6):280. doi: 10.3892/ol.2024.14413. eCollection 2024 Jun.ABSTRACTBreast cancer (BC) is the most common type of cancer found in women. ADP-ribosylation factors (ARFs) are a group of small proteins that bind to GTP and are involved in controlling different cellular functions. The function and evolution of multiple ARFs in BC have remained to be fully elucidated, despite existing studies on this protein family in Homo sapiens and other species. In the present study, a systematic analysis of ARF expression levels in BC tissues compared to normal breast tissues was performed using data from The Cancer...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Lixian Yang Shiyu Zhang Lei Zheng Fanting Kong Pengpeng Pu Xiaowei Li Lining Jia Source Type: research
Preoperative CA19 ‑9 level and dual time point FDG‑PET/CT as strong biological indicators of borderline resectability in pancreatic cancer: A retrospective study
In conclusion, CA19-9 and SUVmax% can be utilized as biological indicators of resectability.PMID:38699663 | PMC:PMC11063755 | DOI:10.3892/ol.2024.14412 (Source: Oncology Letters)
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Kazuki Kobayashi Takahiro Einama Takazumi Tsunenari Naoto Yonamine Mikiya Takao Yasuhiro Takihata Hironori Tsujimoto Hideki Ueno Katsumi Tamura Jiro Ishida Yoji Kishi Source Type: research
Prognostic biomarker NRG2 correlates with autophagy and epithelial ‑mesenchymal transition in breast cancer
Oncol Lett. 2024 Apr 23;27(6):277. doi: 10.3892/ol.2024.14410. eCollection 2024 Jun.ABSTRACTBreast cancer (BRCA) is a leading cause of death in women worldwide, accounting for 31% of female cancer. Autophagy plays a crucial role in cancer progression, however, the function of autophagy-related gene neuroregulatory protein 2 (NRG2) in BRCA and its underlying molecular mechanisms remain unclear. In the present study, the expression of the NRG2 gene in BRCA was significantly down-regulated compared with the normal controls. The low expression level of NRG2 was related to poor survival rate of BRCA. The receiver operating char...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Ruijie Zhou Jinjin Dai Runlong Zhou Mengyi Wang Xiaotong Deng Qing Zhuo Zhenrong Wang Fan Li Di Yao Yao Xu Source Type: research
Expression of nuclear receptor co ‑activator 7 protein is associated with poor prognosis of breast cancer
Oncol Lett. 2024 Apr 23;27(6):278. doi: 10.3892/ol.2024.14411. eCollection 2024 Jun.ABSTRACTNuclear receptor coactivator 7 (NCOA7) is an estrogen receptor binding protein. Its role in breast cancer progression has so far remained elusive. The present study aimed to determine the expression levels of NCOA7 in breast tumor samples and confirmed its potential utility as a breast cancer prognostic biomarker. The expression of NCOA7 was detected by immunohistochemical staining in 241 breast cancer tumor samples and 163 adjacent normal tissue samples. The association of NCOA7 expression with the clinicopathological characteristi...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Ziluo Peng Yanlin Li Song Xia Qian Dai Liang Yin Miao Chen Wannian Yang Genbao Shao Qiong Lin Source Type: research
Association of ADP ‑ribosylation factor family genes with prognosis and immune infiltration of breast cancer
Oncol Lett. 2024 Apr 23;27(6):280. doi: 10.3892/ol.2024.14413. eCollection 2024 Jun.ABSTRACTBreast cancer (BC) is the most common type of cancer found in women. ADP-ribosylation factors (ARFs) are a group of small proteins that bind to GTP and are involved in controlling different cellular functions. The function and evolution of multiple ARFs in BC have remained to be fully elucidated, despite existing studies on this protein family in Homo sapiens and other species. In the present study, a systematic analysis of ARF expression levels in BC tissues compared to normal breast tissues was performed using data from The Cancer...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Lixian Yang Shiyu Zhang Lei Zheng Fanting Kong Pengpeng Pu Xiaowei Li Lining Jia Source Type: research
Preoperative CA19 ‑9 level and dual time point FDG‑PET/CT as strong biological indicators of borderline resectability in pancreatic cancer: A retrospective study
In conclusion, CA19-9 and SUVmax% can be utilized as biological indicators of resectability.PMID:38699663 | PMC:PMC11063755 | DOI:10.3892/ol.2024.14412 (Source: Oncology Letters)
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Kazuki Kobayashi Takahiro Einama Takazumi Tsunenari Naoto Yonamine Mikiya Takao Yasuhiro Takihata Hironori Tsujimoto Hideki Ueno Katsumi Tamura Jiro Ishida Yoji Kishi Source Type: research
Prognostic biomarker NRG2 correlates with autophagy and epithelial ‑mesenchymal transition in breast cancer
Oncol Lett. 2024 Apr 23;27(6):277. doi: 10.3892/ol.2024.14410. eCollection 2024 Jun.ABSTRACTBreast cancer (BRCA) is a leading cause of death in women worldwide, accounting for 31% of female cancer. Autophagy plays a crucial role in cancer progression, however, the function of autophagy-related gene neuroregulatory protein 2 (NRG2) in BRCA and its underlying molecular mechanisms remain unclear. In the present study, the expression of the NRG2 gene in BRCA was significantly down-regulated compared with the normal controls. The low expression level of NRG2 was related to poor survival rate of BRCA. The receiver operating char...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Ruijie Zhou Jinjin Dai Runlong Zhou Mengyi Wang Xiaotong Deng Qing Zhuo Zhenrong Wang Fan Li Di Yao Yao Xu Source Type: research
Expression of nuclear receptor co ‑activator 7 protein is associated with poor prognosis of breast cancer
Oncol Lett. 2024 Apr 23;27(6):278. doi: 10.3892/ol.2024.14411. eCollection 2024 Jun.ABSTRACTNuclear receptor coactivator 7 (NCOA7) is an estrogen receptor binding protein. Its role in breast cancer progression has so far remained elusive. The present study aimed to determine the expression levels of NCOA7 in breast tumor samples and confirmed its potential utility as a breast cancer prognostic biomarker. The expression of NCOA7 was detected by immunohistochemical staining in 241 breast cancer tumor samples and 163 adjacent normal tissue samples. The association of NCOA7 expression with the clinicopathological characteristi...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Ziluo Peng Yanlin Li Song Xia Qian Dai Liang Yin Miao Chen Wannian Yang Genbao Shao Qiong Lin Source Type: research
Association of ADP ‑ribosylation factor family genes with prognosis and immune infiltration of breast cancer
Oncol Lett. 2024 Apr 23;27(6):280. doi: 10.3892/ol.2024.14413. eCollection 2024 Jun.ABSTRACTBreast cancer (BC) is the most common type of cancer found in women. ADP-ribosylation factors (ARFs) are a group of small proteins that bind to GTP and are involved in controlling different cellular functions. The function and evolution of multiple ARFs in BC have remained to be fully elucidated, despite existing studies on this protein family in Homo sapiens and other species. In the present study, a systematic analysis of ARF expression levels in BC tissues compared to normal breast tissues was performed using data from The Cancer...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Lixian Yang Shiyu Zhang Lei Zheng Fanting Kong Pengpeng Pu Xiaowei Li Lining Jia Source Type: research
Preoperative CA19 ‑9 level and dual time point FDG‑PET/CT as strong biological indicators of borderline resectability in pancreatic cancer: A retrospective study
In conclusion, CA19-9 and SUVmax% can be utilized as biological indicators of resectability.PMID:38699663 | PMC:PMC11063755 | DOI:10.3892/ol.2024.14412 (Source: Oncology Letters)
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Kazuki Kobayashi Takahiro Einama Takazumi Tsunenari Naoto Yonamine Mikiya Takao Yasuhiro Takihata Hironori Tsujimoto Hideki Ueno Katsumi Tamura Jiro Ishida Yoji Kishi Source Type: research
Prognostic biomarker NRG2 correlates with autophagy and epithelial ‑mesenchymal transition in breast cancer
Oncol Lett. 2024 Apr 23;27(6):277. doi: 10.3892/ol.2024.14410. eCollection 2024 Jun.ABSTRACTBreast cancer (BRCA) is a leading cause of death in women worldwide, accounting for 31% of female cancer. Autophagy plays a crucial role in cancer progression, however, the function of autophagy-related gene neuroregulatory protein 2 (NRG2) in BRCA and its underlying molecular mechanisms remain unclear. In the present study, the expression of the NRG2 gene in BRCA was significantly down-regulated compared with the normal controls. The low expression level of NRG2 was related to poor survival rate of BRCA. The receiver operating char...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Ruijie Zhou Jinjin Dai Runlong Zhou Mengyi Wang Xiaotong Deng Qing Zhuo Zhenrong Wang Fan Li Di Yao Yao Xu Source Type: research
Expression of nuclear receptor co ‑activator 7 protein is associated with poor prognosis of breast cancer
Oncol Lett. 2024 Apr 23;27(6):278. doi: 10.3892/ol.2024.14411. eCollection 2024 Jun.ABSTRACTNuclear receptor coactivator 7 (NCOA7) is an estrogen receptor binding protein. Its role in breast cancer progression has so far remained elusive. The present study aimed to determine the expression levels of NCOA7 in breast tumor samples and confirmed its potential utility as a breast cancer prognostic biomarker. The expression of NCOA7 was detected by immunohistochemical staining in 241 breast cancer tumor samples and 163 adjacent normal tissue samples. The association of NCOA7 expression with the clinicopathological characteristi...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Ziluo Peng Yanlin Li Song Xia Qian Dai Liang Yin Miao Chen Wannian Yang Genbao Shao Qiong Lin Source Type: research
Association of ADP ‑ribosylation factor family genes with prognosis and immune infiltration of breast cancer
Oncol Lett. 2024 Apr 23;27(6):280. doi: 10.3892/ol.2024.14413. eCollection 2024 Jun.ABSTRACTBreast cancer (BC) is the most common type of cancer found in women. ADP-ribosylation factors (ARFs) are a group of small proteins that bind to GTP and are involved in controlling different cellular functions. The function and evolution of multiple ARFs in BC have remained to be fully elucidated, despite existing studies on this protein family in Homo sapiens and other species. In the present study, a systematic analysis of ARF expression levels in BC tissues compared to normal breast tissues was performed using data from The Cancer...
Source: Oncology Letters - May 3, 2024 Category: Cancer & Oncology Authors: Lixian Yang Shiyu Zhang Lei Zheng Fanting Kong Pengpeng Pu Xiaowei Li Lining Jia Source Type: research
