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Therapy: Pain Management
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Total 26591 results found since Jan 2013.
Contribution of non-socioeconomic factors to healthy quality of life in socioeconomically deprived patients with advanced gastrointestinal cancer: Measuring attributable fraction
CONCLUSIONS: Gait, self-care ability, abdominal distension, nutritional status, weight loss and posture are important determinants of healthy quality of life in patients with advanced gastrointestinal cancer with socioeconomic deprivation, and early identification and strength management of these non-socioeconomic factors may neutralize the negative impact of socioeconomic factors on the quality of life.IMPLICATIONS FOR PRACTICE: This study provides new ideas and intervention entry points for global nurses in practice innovations to improve the quality of life of socioeconomically deprived patients with advanced gastrointe...
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Zifen An Jiaqi Nie Yanfang Huang Pei Fang Xianmei Meng Chunfeng Cai Liping Yu Source Type: research
Progress in the development of TRPV1 small-molecule antagonists: Novel Strategies for pain management
Eur J Med Chem. 2023 Sep 9;261:115806. doi: 10.1016/j.ejmech.2023.115806. Online ahead of print.ABSTRACTTransient receptor potential vanilloid 1 (TRPV1) channels are widely distributed in sensory nerve endings, the central nervous system, and other tissues, functioning as ion channel proteins responsive to thermal pain and chemical stimuli. In recent years, the TRPV1 receptor has garnered significant interest as a potential therapeutic approach for various pain-related disorders, particularly TRPV1 antagonists. The present review offers a comprehensive, systematic exploration of both first- and second-generation TRPV1 anta...
Source: European Journal of Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Kun Zhu Lin Wang TingTing Liao Wen Li Jing Zhou Yaodong You Jianyou Shi Source Type: research
Contribution of non-socioeconomic factors to healthy quality of life in socioeconomically deprived patients with advanced gastrointestinal cancer: Measuring attributable fraction
CONCLUSIONS: Gait, self-care ability, abdominal distension, nutritional status, weight loss and posture are important determinants of healthy quality of life in patients with advanced gastrointestinal cancer with socioeconomic deprivation, and early identification and strength management of these non-socioeconomic factors may neutralize the negative impact of socioeconomic factors on the quality of life.IMPLICATIONS FOR PRACTICE: This study provides new ideas and intervention entry points for global nurses in practice innovations to improve the quality of life of socioeconomically deprived patients with advanced gastrointe...
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Zifen An Jiaqi Nie Yanfang Huang Pei Fang Xianmei Meng Chunfeng Cai Liping Yu Source Type: research
Application of behavioral economic strategies to enhance recruitment into a pediatric randomized clinical trial for postoperative pain relief: A randomized clinical trial
CONCLUSION: Either approach would be sufficient for patient recruitment for this type of clinical trial since the overall intention to enroll rate was 77%.PMID:37712489 | DOI:10.1111/pan.14755
Source: Paediatric Anaesthesia - September 15, 2023 Category: Anesthesiology Authors: Anitra Karthic Zandantsetseg Orgil Nguyen K Tram Julie Rice-Weimer Jack Stevens Vanessa A Olbrecht Source Type: research
Cardiac Tamponade Secondary to Hemorrhagic Pericardial Effusion: A Complication of STEMI
Conclusion: The differential for hemodynamic compromise in a patient with STEMI is broad, but quickly distinguishing pump failure from other life-threatening causes of shock is imperative to dictate time-sensitive management decisions. The presence of a hemorrhagic pericardial effusion in the setting of STEMI is a surrogate marker for a severe infarct and can help the bedside physician determine whether a patient will be better served in the catheterization lab for revascularization or in the operating room for surgical repair.PMID:37711482 | PMC:PMC10498953 | DOI:10.31486/toj.23.0023
Source: Pain Physician - September 15, 2023 Category: Anesthesiology Authors: Marvin Kajy Amy Rechenberg Connor Kerndt Kevin Wolschleger Source Type: research
When Does Intervention End and Surgery Begin? The Role of Interventional Pain Management in the Treatment of Spine Pathology
AbstractPurpose of ReviewRecent advances in the field of interventional pain management (IPM) involve minimally invasive procedures such as percutaneous lumbar decompression, interspinous spacer placement, interspinous-interlaminar fusion and sacroiliac joint fusion. These developments have received pushback from surgical professional societies, who state spinal instrumentation and arthrodesis should only be performed by spine surgeons. The purpose of this review is to evaluate the validity of this claim. A literature search was conducted on Google Scholar and PubMed databases. Articles were included which examined IPM in ...
Source: Current Pain and Headache Reports - September 15, 2023 Category: Neurology Source Type: research
Treatment of digital ulcers in systemic sclerosis: recent developments and future perspectives
AbstractDigital ulcers (DUs) comprise the main manifestation of vasculopathy and are a major cause of disability in patients with systemic sclerosis (SSc). A literature search in Web of Science, PubMed and Directory of Open Access Journals was performed in December 2022 to identify articles published in the last decade regarding the management of DUs. Prostacyclin analogues, endothelin antagonists and phosphodiesterase 5 inhibitors have shown promising results both as a stand-alone treatment and in combination for the treatment of existing and prevention of new DUs. Moreover, autologous fat grafting and botulinum toxin inj...
Source: Clinical Rheumatology - September 14, 2023 Category: Rheumatology Source Type: research
Stepped collaborative care for pain and posttraumatic stress disorder after major trauma: a randomized controlled feasibility trial
CONCLUSIONS: Stepped collaborative care was low-cost, feasible, and acceptable to people at risk of PTSD or pain after major trauma.IMPLICATIONS FOR REHABILITATIONAfter hospitalization for injury, people can experience difficulty accessing timely support to manage posttraumatic stress, pain and other concerns.Stepped case management-based interventions that provide individualized support and collaborative care have reduced posttraumatic stress symptom severity for patients admitted to American trauma centers.We showed that this model of care could be adapted to target pain and mental health in the trauma system in Victoria...
Source: Disability and Rehabilitation - September 14, 2023 Category: Rehabilitation Authors: Melita J Giummarra Sandra Reeder Scott Williams Anna Devlin Rose Knol Jennie Ponsford Carolyn A Arnold Alex Konstantatos Belinda J Gabbe Hance Clarke Joel Katz Fiona Mitchell Elizabeth Robinson Douglas Zatzick Source Type: research
Cryotherapy following total knee replacement
CONCLUSIONS: The certainty of evidence was low for blood loss, pain and range of motion, and very low for transfusion rate, function, total adverse events and withdrawals from adverse events. We are uncertain whether cryotherapy improves transfusion rate, function, total adverse events or withdrawals from adverse events. We downgraded evidence for bias, indirectness, imprecision and inconsistency. Hence, the potential benefits of cryotherapy on blood loss, pain and range of motion may be too small to justify its use. More well-designed randomised controlled trials focusing especially on clinically meaningful outcomes, such...
Source: Cochrane Database of Systematic Reviews - September 14, 2023 Category: General Medicine Authors: Ashwin Aggarwal Sam Adie Ian A Harris Justine Naylor Source Type: research
The Edmonton Symptom Assessment Scale in Heart Failure: A Systematic Review
CONCLUSION: This review highlighted the Edmonton Symptom Assessment Scale as a predictive instrument to identify symptom burden, symptom clusters, and symptom changes for patients living with heart failure. The clinical use of the Edmonton Symptom Assessment Scale may identify treatment priorities, promote self-management, inform the treatment plan, and advance effective therapeutic adjustments. The symptom burden in heart failure is high, and improving the symptom experience is an important focus of future healthcare interventions. The Edmonton Symptom Assessment Scale has utility in heart failure management due to psycho...
Source: The Journal of Cardiovascular Nursing - September 14, 2023 Category: Nursing Authors: Reiko Asano Kelley M Anderson Binu Koirala Martha Abshire Cheryl Dennison Himmelfarb Patricia M Davidson Source Type: research
Cryotherapy following total knee replacement
CONCLUSIONS: The certainty of evidence was low for blood loss, pain and range of motion, and very low for transfusion rate, function, total adverse events and withdrawals from adverse events. We are uncertain whether cryotherapy improves transfusion rate, function, total adverse events or withdrawals from adverse events. We downgraded evidence for bias, indirectness, imprecision and inconsistency. Hence, the potential benefits of cryotherapy on blood loss, pain and range of motion may be too small to justify its use. More well-designed randomised controlled trials focusing especially on clinically meaningful outcomes, such...
Source: Cochrane Database of Systematic Reviews - September 14, 2023 Category: General Medicine Authors: Ashwin Aggarwal Sam Adie Ian A Harris Justine Naylor Source Type: research
Sudden onset headaches in paediatric emergency departments: diagnosis and management
Ital J Pediatr. 2023 Sep 14;49(1):122. doi: 10.1186/s13052-023-01526-4.ABSTRACTHeadache is one of the most common pain syndromes in the paediatric population. Headaches are classified as primary (migraine, tension-type headaches, trigeminal autonomic cephalalgia and other primary headaches) or secondary (e.g. post-traumatic). Non-febrile, non-traumatic headaches represent 1% of all paediatric emergency departments (PED) visits. Many patients present with an acute, moderate to severe pain, sometimes with a sudden onset. Sudden onset headache can be the main symptom of life-threatening neurological conditions as well as a si...
Source: Pain Physician - September 14, 2023 Category: Anesthesiology Authors: L éa Lenglart C écile Monteil Eugenia Spreafico Thomas Moulding Luigi Titomanlio Source Type: research
Application of analgesics in emergency services in Germany: a survey of the medical directors
CONCLUSION: Effective analgesics are available for EMS staff in Germany, the approach to improvement lies in the area of application. For this purpose, the adaptations of the legal framework as well as the creation of a guideline for prehospital analgesia are useful.PMID:37710177 | DOI:10.1186/s12873-023-00878-8
Source: Pain Physician - September 14, 2023 Category: Anesthesiology Authors: Signe Vilcane Olga Scharonow Christian Weilbach Maximilian Scharonow Source Type: research
Association between obesity and likelihood of remission or low disease activity status in psoriatic arthritis applying index-based and patient-based definitions of remission: a cross-sectional study
CONCLUSION: PsA patients with comorbid obesity were 2.5-3 folds less likely to be in remission/LDA by composite scores compared with non-obese patients; however, remission/LDA rates were similar based on the patients' opinion. PsA patients with comorbid obesity may have different disease profiles and require individualised management.PMID:37709527 | DOI:10.1136/rmdopen-2023-003157
Source: Pain Physician - September 14, 2023 Category: Anesthesiology Authors: Ying Ying Leung Lihi Eder Ana-Maria Orbai Laura C Coates Maarten de Wit Josef S Smolen Uta Kiltz Pen élope Palominos Juan D Canete Rossana Scrivo Andra Balanescu Emanuelle Dernis Sandra Meisalu Martin Soubrier Umut Kalyoncu Laure Gossec Source Type: research
