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Association of participants who screened positive for night eating syndrome with physical health, sleep problems, and weight status in an Australian adult population
CONCLUSIONS: Several physical health problems were found to be significantly associated with the spNES group including sleep problems, increased BMI, increased levels of pain and lower self-reported physical health-related quality of life. Consequently, future research exploring the complex interaction between NES and these medical conditions may provide further insight into the diagnosis, screening tools and management of NES. Additionally, this study highlights the need for future studies which use larger population-based samples.LEVEL OF EVIDENCE: Level III. Evidence obtained from well-designed cohort or case-control an...
Source: Eating and weight disorders : EWD - September 20, 2023 Category: Eating Disorders & Weight Management Authors: Sai Janani Sakthivel Phillipa Hay Stephen Touyz David Currow Haider Mannan Source Type: research

Optimizing surgical management of facet cysts of the lumbar spine: systematic review, meta-analysis, and local case series of 1251 patients
CONCLUSIONS: While PCR is less invasive, it may have high rates of same-level recurrence and revision surgery. Recurrence and revision rates for modalities such as ECR were not significantly different from those of OCR. While concomitant arthrodesis is more invasive, it might lead to lower recurrence rates and lower rates of subsequent revision surgery. Given the limitations of our case series and literature review, prospective, randomized studies are needed.PMID:37728373 | DOI:10.3171/2023.6.SPINE23404
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Arjun Ganga Owen P Leary Aayush Setty Kevin Xi Albert E Telfeian Adetokunbo A Oyelese Tianyi Niu Joaquin Q Camara-Quintana Ziya L Gokaslan Patricia Zadnik Sullivan Jared S Fridley Source Type: research

Pain management for liver transplant recipients
We present current evidence-based literature that reviews optimal pain management strategies for this challenging patient demographic.RECENT FINDINGS: Multiple studies have shown that thoracic epidurals provide superior pain control in open hepatic resections. Recent data suggests thoracic epidurals may be safely considered in select liver transplant recipients with normal preoperative coagulation status; however, this evidence is limited, and further studies are needed. When the risks of coagulopathy prohibit epidural placement, truncal blocks such as transversus abdominis plane blocks or quadratus lumborum blocks and abd...
Source: Current Opinion in Organ Transplantation - September 20, 2023 Category: Transplant Surgery Authors: Simrat Kaur Patrick Henthorn Adrian Hendrickse Source Type: research

VEIN STEP: A Prospective, Observational, International Study to Assess Effectiveness of Conservative Treatments in Chronic Venous Disease
CONCLUSION: In this prospective study conducted in the real-world setting, treatment with conservative therapy, in particular MPFF, was associated with meaningful improvements in the clinical signs and symptoms of disease as well as in quality of life in patients with CVD.TRIAL REGISTRATION: ClinicalTrials.gov identifier NCT04574375.PMID:37728696 | DOI:10.1007/s12325-023-02643-6
Source: Pain Physician - September 20, 2023 Category: Anesthesiology Authors: Zoubida Tazi Mezalek Toni Feodor Larisa Chernukha Zhong Chen Ana Rueda Ignacio Escotto S ánchez Alejandro Jos é González Ochoa Joanna Chirol Vanessa Blanc-Guillemaud Caroline Lohier-Durel Jorge Hernando Ulloa Source Type: research

Microfragmented adipose tissue in the treatment of a full-thickness supraspinatus tear: a case report
Regen Med. 2023 Sep 20. doi: 10.2217/rme-2023-0086. Online ahead of print.ABSTRACTA 70-year-old female presented with an 8-month history of right anterior shoulder pain and weakness, unresolved with conservative management. Among other shoulder pathology, the patient was diagnosed with a full-thickness supraspinatus tear and elected to proceed with the microfragmented adipose tissue procedure to treat the injured tendon and nearby relevant structures. Improvements in pain and function were documented along with progressive healing of the supraspinatus on ultrasound and MRI following the procedure. This case demonstrates th...
Source: Regenerative Medicine - September 20, 2023 Category: Genetics & Stem Cells Authors: John L Ferrell Alanna Dodson Joshua Martin Source Type: research

Is low-dose naltrexone effective in chronic pain management?
J Fam Pract. 2023 Sep;72(7):320-321. doi: 10.12788/jfp.0654.ABSTRACTYES. Low-dose naltrexone is as effective as amitriptyline in the treatment of painful diabetic neuropathy and has a superior safety profile (strength of recommendation [SOR], B; single randomized controlled trial [RCT]). Low-dose naltrexone significantly reduced pain by 32% in inflammatory conditions and 44% in neuropathic conditions (SOR, B; single retrospective cohort study). Doses as low as 5.4 mg were found to reduce pain in 95% of patients with fibromyalgia (SOR, B; single prospective dose-response study).PMID:37729143 | DOI:10.12788/jfp.0654
Source: The Journal of Family Practice - September 20, 2023 Category: Practice Management Authors: Roxanne Radi Harriet Huang Jason Rivera Corey Lyon Kristen DeSanto Source Type: research

Pain management for liver transplant recipients
We present current evidence-based literature that reviews optimal pain management strategies for this challenging patient demographic.RECENT FINDINGS: Multiple studies have shown that thoracic epidurals provide superior pain control in open hepatic resections. Recent data suggests thoracic epidurals may be safely considered in select liver transplant recipients with normal preoperative coagulation status; however, this evidence is limited, and further studies are needed. When the risks of coagulopathy prohibit epidural placement, truncal blocks such as transversus abdominis plane blocks or quadratus lumborum blocks and abd...
Source: Current Opinion in Organ Transplantation - September 20, 2023 Category: Transplant Surgery Authors: Simrat Kaur Patrick Henthorn Adrian Hendrickse Source Type: research

Is low-dose naltrexone effective in chronic pain management?
J Fam Pract. 2023 Sep;72(7):320-321. doi: 10.12788/jfp.0654.ABSTRACTYES. Low-dose naltrexone is as effective as amitriptyline in the treatment of painful diabetic neuropathy and has a superior safety profile (strength of recommendation [SOR], B; single randomized controlled trial [RCT]). Low-dose naltrexone significantly reduced pain by 32% in inflammatory conditions and 44% in neuropathic conditions (SOR, B; single retrospective cohort study). Doses as low as 5.4 mg were found to reduce pain in 95% of patients with fibromyalgia (SOR, B; single prospective dose-response study).PMID:37729143 | DOI:10.12788/jfp.0654
Source: The Journal of Family Practice - September 20, 2023 Category: Practice Management Authors: Roxanne Radi Harriet Huang Jason Rivera Corey Lyon Kristen DeSanto Source Type: research

Optimizing surgical management of facet cysts of the lumbar spine: systematic review, meta-analysis, and local case series of 1251 patients
CONCLUSIONS: While PCR is less invasive, it may have high rates of same-level recurrence and revision surgery. Recurrence and revision rates for modalities such as ECR were not significantly different from those of OCR. While concomitant arthrodesis is more invasive, it might lead to lower recurrence rates and lower rates of subsequent revision surgery. Given the limitations of our case series and literature review, prospective, randomized studies are needed.PMID:37728373 | DOI:10.3171/2023.6.SPINE23404
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Arjun Ganga Owen P Leary Aayush Setty Kevin Xi Albert E Telfeian Adetokunbo A Oyelese Tianyi Niu Joaquin Q Camara-Quintana Ziya L Gokaslan Patricia Zadnik Sullivan Jared S Fridley Source Type: research

Association of participants who screened positive for night eating syndrome with physical health, sleep problems, and weight status in an Australian adult population
CONCLUSIONS: Several physical health problems were found to be significantly associated with the spNES group including sleep problems, increased BMI, increased levels of pain and lower self-reported physical health-related quality of life. Consequently, future research exploring the complex interaction between NES and these medical conditions may provide further insight into the diagnosis, screening tools and management of NES. Additionally, this study highlights the need for future studies which use larger population-based samples.LEVEL OF EVIDENCE: Level III. Evidence obtained from well-designed cohort or case-control an...
Source: Eating and weight disorders : EWD - September 20, 2023 Category: Eating Disorders & Weight Management Authors: Sai Janani Sakthivel Phillipa Hay Stephen Touyz David Currow Haider Mannan Source Type: research

Microfragmented adipose tissue in the treatment of a full-thickness supraspinatus tear: a case report
Regen Med. 2023 Sep 20. doi: 10.2217/rme-2023-0086. Online ahead of print.ABSTRACTA 70-year-old female presented with an 8-month history of right anterior shoulder pain and weakness, unresolved with conservative management. Among other shoulder pathology, the patient was diagnosed with a full-thickness supraspinatus tear and elected to proceed with the microfragmented adipose tissue procedure to treat the injured tendon and nearby relevant structures. Improvements in pain and function were documented along with progressive healing of the supraspinatus on ultrasound and MRI following the procedure. This case demonstrates th...
Source: Regenerative Medicine - September 20, 2023 Category: Genetics & Stem Cells Authors: John L Ferrell Alanna Dodson Joshua Martin Source Type: research

A 50-something with Regular Wide Complex Tachycardia: What to do if electrical cardioversion does not work?
Case submitted by anonymous. Written by Smith.  Ken ' s piece at the bottom is excellent.A 50-something presented with sudden onset palpitations 8 hrs prior while sitting at desk at work. He had concurrent sharp substernal chest pain that resolved, but palpitations continued.Over past 3 months, he has had similar intermittent episodes of sharp chest pain while running, but none at rest. Past medical history includes coronary stenting 17 years prior. A brief chart review revealed his most recent echo in 2018, with LV EF 67%, “very small” inferior wall motion abnormality.Initial ED ECG:What do you think?This wa...
Source: Dr. Smith's ECG Blog - September 20, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

A 50-something with Regular Wide Complex Tachycardiaa: What to do if electrical cardioversion does not work?
Case submitted by anonymous. Written by Smith.  Ken ' s piece at the bottom is excellent.A 50-something presented with sudden onset palpitations 8 hrs prior while sitting at desk at work. He had concurrent sharp substernal chest pain that resolved, but palpitations continued.Over past 3 months, he has had similar intermittent episodes of sharp chest pain while running, but none at rest. Past medical history includes coronary stenting 17 years prior. A brief chart review revealed his most recent echo in 2018, with LV EF 67%, “very small” inferior wall motion abnormality.Initial ED ECG:What do you think?This wa...
Source: Dr. Smith's ECG Blog - September 20, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs