Filtered By:
Education: Learning

This page shows you your search results in order of date. This is page number 4.

Order by Relevance | Date

Total 125738 results found since Jan 2013.

The effects of carvacrol and p-cymene on A β < sub > 1-42 < /sub > -induced long-term potentiation deficit in male rats
CONCLUSIONS: These data indicate that CAR or p-cymene can ameliorate Aβ-associated changes in synaptic plasticity. Surprisingly, the combination of CAR and p-cymene did not yield the same effect, suggesting a potential interaction between the two substances.PMID:37727020 | DOI:10.1111/cns.14459
Source: CNS Neuroscience and Therapeutics - September 20, 2023 Category: Neuroscience Authors: Sahifeh Kazemi Samaneh Safari Somayeh Komaki Seyed Asaad Karimi Zoleikha Golipoor Alireza Komaki Source Type: research

Association between immunohistochemical markers and tumor progression following resection of spinal chordomas: a multicenter study
CONCLUSIONS: These IHC variables with tree-based machine learning tools successfully demonstrate a high capacity to identify a patient's tumor progression pattern with an accuracy of 66%. Pancytokeratin, EMA, cytokeratin A1/A3, and S100 protein were the IHC drivers of a low tumor progression. This shows the power of machine learning algorithms in analyzing and predicting outcomes of rare conditions in a small sample size.PMID:37728388 | DOI:10.3171/2023.6.SPINE23348
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Abdul Karim Ghaith Oluwaseun O Akinduro Carlos Perez-Vega Antonio Bon Nieves Kingsley Abode-Iyamah Naresh Patel Maziyar Kalani Michelle J Clarke Peter Rose Mohamad Bydon Source Type: research

Effects of Radiofrequency Electromagnetic Field (RF-EMF) exposure on pregnancy and birth outcomes: A systematic review of experimental studies on non-human mammals
In conclusion, in utero RF-EMF exposure does not have a detrimental effect on fecundity and likely affects offspring health at birth, based on the meta-analysis of studies in experimental mammals on litter size and fetal weight, respectively. Regarding possible delayed effects of in utero exposure, RF-EMF probably does not affect offspring brain weight and may not decrease female offspring fertility; on the other hand, RF-EMF may have a detrimental impact on neurobehavioural functions, varying in magnitude for different endpoints, but these last findings are very uncertain. Further research is needed on the effects at birt...
Source: Environment International - September 20, 2023 Category: Environmental Health Authors: Eugenia Cordelli Lucia Ardoino Barbara Benassi Claudia Consales Patrizia Eleuteri Carmela Marino Maurizio Sciortino Paola Villani Martin H Brinkworth Guangdi Chen James P McNamee Andrew W Wood Lea Belackova Jos Verbeek Francesca Pacchierotti Source Type: research

Prediction of groundwater quality index to assess suitability for drinking purpose using averaged neural network and geospatial analysis
This study revealed that over 50 % of the evaluated wells (Total 8326 wells) were inappropriate as sources of drinking water, indicating a pressing need for policy revision. The averaged neural network model achieved a high predictive accuracy of approximately 95 % for GQI grades, outperforming other classification models. The introduction of 2D spatial analysis in conjunction with machine learning algorithms notably increased the predictive accuracy for unevenly distributed groundwater samples. Moreover, this combined approach enabled the intuitive visualization of groundwater vulnerability across various regions, which c...
Source: Ecotoxicology and Environmental Safety - September 20, 2023 Category: Environmental Health Authors: Seok Hyun Ahn Do Hwan Jeong MoonSu Kim Tae Kwon Lee Hyun-Koo Kim Source Type: research

Road map for personalized exercise medicine in T2DM
Trends Endocrinol Metab. 2023 Sep 18:S1043-2760(23)00166-2. doi: 10.1016/j.tem.2023.08.013. Online ahead of print.ABSTRACTThe number of patients with type 2 diabetes mellitus (T2DM) is rising at an alarming rate. Regular physical activity and exercise are cornerstones in the therapy of T2DM. While a one-size-fits-all approach fails to account for many between-subject differences, the use of personalized exercise medicine has the potential of optimizing health outcomes. Here, a road map for personalized exercise therapy targeted at patients with T2DM is presented. It considers secondary complications, glucose management, re...
Source: Trends in Endocrinology and Metabolism: TEM - September 20, 2023 Category: Endocrinology Authors: Christian Brinkmann Source Type: research

Increased hippocampal CREB phosphorylation after retrieval of remote contextual fear memories in Carioca High-conditioned Freezing rats
Neurobiol Learn Mem. 2023 Sep 18:107828. doi: 10.1016/j.nlm.2023.107828. Online ahead of print.ABSTRACTThe participation of the hippocampal formation in consolidation and reconsolidation of contextual fear memories has been widely recognized and known to be dependent on the activation of the cAMP response element (CRE) binding protein (CREB) pathway. Recent findings have challenged the prevailing view that over time contextual fear memories migrate to neocortical circuits and no longer require the hippocampus for retrieval of remote fearful memories. It has also recently been found that this brain structure is important fo...
Source: Neurobiology of Learning and Memory - September 20, 2023 Category: Neurology Authors: Fernanda Nunes Bruna Lotufo Yury Velho Martins Lages S ílvia Maisonnette Thomas Krahe Antonio Pedro Mello Cruz J Landeira-Fernandez Source Type: research

Stress effects on spatial memory retrieval and brain c-Fos expression pattern in adults are modulated by early nicotine exposure
Neurobiol Learn Mem. 2023 Sep 18:107831. doi: 10.1016/j.nlm.2023.107831. Online ahead of print.ABSTRACTThe cognitive effects of nicotine are linked to persistent modifications in extended neural systems that regulate cognitive and emotional processes, and these changes occur during development. Additionally, acute stress has modulatory effects on cognition that involve broad neural systems and can be influenced by prior environmental challenges. The effects of nicotine and stress may be interconnected, leading to modifications in a network of shared brain substrates. Here, we explored the interaction between nicotine and s...
Source: Neurobiology of Learning and Memory - September 20, 2023 Category: Neurology Authors: Jos é L Solano Carlos Novoa Marisol R Lamprea Leonardo A Ortega Source Type: research

Learning to drive with neurological conditions: profile of users of an adapted driver training program and cognitive factors associated with success
CONCLUSION: These results suggest that approximately half of the persons enrolled in a driver training program designed for learners with neurological conditions, obtain a driver's license; and that attention, and to a lesser extent executive functioning and working memory, are related to driving program success.IMPLICATIONS FOR REHABILITATIONIn individual with neurological conditions, learning how to drive can be challenging.An adapted driver training program, involving collaboration between driving instructors and healthcare professionals, simplification of theoretical learning, and increasing driving practice opportunit...
Source: Disability and Rehabilitation - September 20, 2023 Category: Rehabilitation Authors: Adam Fahmi Mathieu Garon Alexandra Ribon-Demars Laurie Dubois Martin Caouette Marie- Ève Lamontagne Simon Beaulieu-Bonneau Source Type: research

Recruiting the next generation of rural healthcare practitioners: the impact of an online mentoring program on career and educational goals in rural youth
CONCLUSION: This study suggests that online mentoring can direct rural youths' career interests toward, and provide a refreshing approach to imparting information about, healthcare professions. Although its longitudinal impacts need to be studied, the changes in attitudes and gains in knowledge observed while participating in this program put these students on the right track for eventually transitioning to health science programs. Arming rural youth with the knowledge and motivation to pursue healthcare careers through near-peer mentorship could be a unique strategy for increasing rural student representation in health sc...
Source: Rural Remote Health - September 20, 2023 Category: Rural Health Authors: Juliet Oshiro Katherine Wisener Angela L Nash Blair Stanley Sandra Jarvis-Selinger Source Type: research

Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice
In this study we tested the hypotheses that 1) myelin structural alterations in 3xTg-AD mice would be related to abnormalities in oligodendrocyte lineage cells, resulting in impaired learning and memory, and 2) a 6-month aerobic exercise intervention would have beneficial effects on such alterations. Two-month-old male 3xTg-AD mice were randomly assigned to a control (AC) or an exercise (AE) group, and age-matched male C57BL/6;129 mice were also randomly assigned to a normal control (NC) or an exercise (NE) group, with n = 12 in each group. Mice in the exercise groups were trained on a motor-drive treadmill, 60 min per day...
Source: Experimental Gerontology - September 20, 2023 Category: Geriatrics Authors: Dan Qiu Shi Zhou James Donnelly Dongdong Xia Li Zhao Source Type: research

Effectiveness of a vision-based handle trajectory monitoring system in studying robotic suture operation
J Robot Surg. 2023 Sep 20. doi: 10.1007/s11701-023-01713-9. Online ahead of print.ABSTRACTData on surgical robots are not openly accessible, limiting further study of the operation trajectory of surgeons' hands. Therefore, a trajectory monitoring system should be developed to examine objective indicators reflecting the characteristic parameters of operations. 20 robotic experts and 20 first-year residents without robotic experience were included in this study. A dry-lab suture task was used to acquire relevant hand performance data. Novices completed training on the simulator and then performed the task, while the expert t...
Source: Hand Surgery - September 20, 2023 Category: Surgery Authors: Gaojie Chen Lu Li Jacques Hubert Bin Luo Kun Yang Xinghuan Wang Source Type: research

A 50-something with Regular Wide Complex Tachycardia: What to do if electrical cardioversion does not work?
Case submitted by anonymous. Written by Smith.  Ken ' s piece at the bottom is excellent.A 50-something presented with sudden onset palpitations 8 hrs prior while sitting at desk at work. He had concurrent sharp substernal chest pain that resolved, but palpitations continued.Over past 3 months, he has had similar intermittent episodes of sharp chest pain while running, but none at rest. Past medical history includes coronary stenting 17 years prior. A brief chart review revealed his most recent echo in 2018, with LV EF 67%, “very small” inferior wall motion abnormality.Initial ED ECG:What do you think?This wa...
Source: Dr. Smith's ECG Blog - September 20, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

A 50-something with Regular Wide Complex Tachycardiaa: What to do if electrical cardioversion does not work?
Case submitted by anonymous. Written by Smith.  Ken ' s piece at the bottom is excellent.A 50-something presented with sudden onset palpitations 8 hrs prior while sitting at desk at work. He had concurrent sharp substernal chest pain that resolved, but palpitations continued.Over past 3 months, he has had similar intermittent episodes of sharp chest pain while running, but none at rest. Past medical history includes coronary stenting 17 years prior. A brief chart review revealed his most recent echo in 2018, with LV EF 67%, “very small” inferior wall motion abnormality.Initial ED ECG:What do you think?This wa...
Source: Dr. Smith's ECG Blog - September 20, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

Resilience perspective on healthcare professionals adaptations to changes and challenges resulting from the COVID-19 pandemic: a meta-synthesis
Conclusion Healthcare professionals demonstrated significant adaptive capacity when faced with challenges imposed by the COVID-19 pandemic. Several adaptations were identified as beneficial for future organisational healthcare service changes, while others exposed weaknesses in healthcare system designs and capacity, leading to dysfunctional adaptations. Healthcare professionals’ experiences working during the COVID-19 pandemic present a unique opportunity to learn how healthcare systems rapidly respond to changes, and how resilient healthcare services can be built globally.
Source: BMJ Open - September 20, 2023 Category: General Medicine Authors: Knutsen Glette, M., Ludlow, K., Wiig, S., Bates, D. W., Austin, E. E. Tags: Open access, Health services research, COVID-19 Source Type: research

Simulating Isotropic Raman Spectra of O-H Stretching Mode in Liquid H2O based on a Machine Learning Potential: the Influence of Vibrational Couplings
In this study, we trained a deep potential (DP) for H2O, an accurate machine learning (ML) potential. We performed molecular dynamics (MD) simulations of liquid water using the DP model... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 19, 2023 Category: Chemistry Authors: Hujun Shen Source Type: research