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Drug: Estradiol

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Total 6427 results found since Jan 2013.

Compare the Efficacy of Dienogest and the Levonorgestrel Intrauterine System in Women with Adenomyosis
This study enrolled 117 women with symptomatic adenomyosis who visited our hospital from May 1, 2019, to June 30, 2022. Participants were randomized to either the LNG-IUS group (n = 48) or the DNG group (n = 79) in an as-controlled clinical trial for 36 months. Visual analog scale (VAS) scores, uterine volume, endometrial thickness, serum carcinoma antigen 125 level, estradiol, follicle-stimulating hormone, luteinizing hormone, and side effects were assessed to compare the efficacy of LNG-IUS and DNG.FINDINGS: The VAS pain score was significantly decreased in both groups after 3 months of treatment. Three months later, pat...
Source: Clinical Therapeutics - August 20, 2023 Category: Drugs & Pharmacology Authors: Weina Guo Yuchen Lin Sijian Hu Yi Shen Source Type: research

The effect of bladder function on the efficacy of transurethral prostatectomy in patients with benign prostatic hyperplasia: a retrospective, single-center study
Asian J Androl. 2023 Aug 11. doi: 10.4103/aja202327. Online ahead of print.ABSTRACTWe investigated the impact and predictive value of bladder function in patients with benign prostatic hyperplasia (BPH) on the efficacy of transurethral prostatectomy. Symptomatic, imaging, and urodynamic data of patients who underwent transurethral prostatectomy at West China Hospital of Sichuan University (Chengdu, China) from July 2019 to December 2021 were collected. Follow-up data included the quality of life (QoL), International Prostate Symptom Score (IPSS), and IPSS storage and voiding (IPSS-s and IPSS-v). Moreover, urinary creatinin...
Source: Asian Journal of Andrology - August 18, 2023 Category: Urology & Nephrology Authors: Jin Li Xian-Yan-Ling Yi Ze-Yu Chen Bo Chen Yin Huang Da-Zhou Liao Pu-Ze Wang De-Hong Cao Jian-Zhong Ai Liang-Ren Liu Source Type: research

Decrease in ER ɑ within the BNST of sexually naïve male rats following an encounter with a novel female
Behav Brain Res. 2023 Aug 16:114626. doi: 10.1016/j.bbr.2023.114626. Online ahead of print.ABSTRACTTestosterone and its metabolites facilitate male-typical social behaviors in sexually experienced animals. The metabolite estradiol acts on estrogen receptors (ERs) within the bed nucleus of the stria terminalis (BNST) to facilitate socio-sexual behaviors. While circulating testosterone does not increase in naïve males, aromatase-expressing neurons within the BNST of naïve males are necessary for sex recognition, suggesting that local estradiol production may be responsible. In the present study, we examined ERɑ-immunoreac...
Source: Brain Research - August 18, 2023 Category: Neurology Authors: Brianna M Bembenek Julia E Meyers-Manor Robin M Forbes-Lorman Source Type: research

The effect of bladder function on the efficacy of transurethral prostatectomy in patients with benign prostatic hyperplasia: a retrospective, single-center study
Asian J Androl. 2023 Aug 11. doi: 10.4103/aja202327. Online ahead of print.ABSTRACTWe investigated the impact and predictive value of bladder function in patients with benign prostatic hyperplasia (BPH) on the efficacy of transurethral prostatectomy. Symptomatic, imaging, and urodynamic data of patients who underwent transurethral prostatectomy at West China Hospital of Sichuan University (Chengdu, China) from July 2019 to December 2021 were collected. Follow-up data included the quality of life (QoL), International Prostate Symptom Score (IPSS), and IPSS storage and voiding (IPSS-s and IPSS-v). Moreover, urinary creatinin...
Source: Asian Journal of Andrology - August 18, 2023 Category: Urology & Nephrology Authors: Jin Li Xian-Yan-Ling Yi Ze-Yu Chen Bo Chen Yin Huang Da-Zhou Liao Pu-Ze Wang De-Hong Cao Jian-Zhong Ai Liang-Ren Liu Source Type: research

Oestrogen treatment restores dentate gyrus development in premature newborns by IGF1 regulation
J Cell Mol Med. 2023 Aug 18. doi: 10.1111/jcmm.17816. Online ahead of print.ABSTRACTPrematurely-born infants cared for in the neonatal units suffer from memory and learning deficits. Prematurity diminishes neurogenesis and synaptogenesis in the hippocampal dentate gyrus (DG). This dysmaturation of neurons is attributed to elevated PSD95, NMDR2A, and IGF1 levels. Since oestrogen treatment plays key roles in the development and plasticity of DG, we hypothesized that 17β-estradiol (E2) treatment would ameliorate neurogenesis and synaptogenesis in the DG, reversing cognitive deficits in premature newborns. Additionally, E2-in...
Source: J Cell Mol Med - August 18, 2023 Category: Molecular Biology Authors: Deep R Sharma Bokun Cheng Rauhin Sahu Xusheng Zhang Rana Mehdizadeh Divya Singh Dumitru Iacobas Praveen Ballabh Source Type: research

Decrease in ER ɑ within the BNST of sexually naïve male rats following an encounter with a novel female
Behav Brain Res. 2023 Aug 16:114626. doi: 10.1016/j.bbr.2023.114626. Online ahead of print.ABSTRACTTestosterone and its metabolites facilitate male-typical social behaviors in sexually experienced animals. The metabolite estradiol acts on estrogen receptors (ERs) within the bed nucleus of the stria terminalis (BNST) to facilitate socio-sexual behaviors. While circulating testosterone does not increase in naïve males, aromatase-expressing neurons within the BNST of naïve males are necessary for sex recognition, suggesting that local estradiol production may be responsible. In the present study, we examined ERɑ-immunoreac...
Source: Behavioural Brain Research - August 18, 2023 Category: Neurology Authors: Brianna M Bembenek Julia E Meyers-Manor Robin M Forbes-Lorman Source Type: research

Oestrogen treatment restores dentate gyrus development in premature newborns by IGF1 regulation
J Cell Mol Med. 2023 Aug 18. doi: 10.1111/jcmm.17816. Online ahead of print.ABSTRACTPrematurely-born infants cared for in the neonatal units suffer from memory and learning deficits. Prematurity diminishes neurogenesis and synaptogenesis in the hippocampal dentate gyrus (DG). This dysmaturation of neurons is attributed to elevated PSD95, NMDR2A, and IGF1 levels. Since oestrogen treatment plays key roles in the development and plasticity of DG, we hypothesized that 17β-estradiol (E2) treatment would ameliorate neurogenesis and synaptogenesis in the DG, reversing cognitive deficits in premature newborns. Additionally, E2-in...
Source: Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Deep R Sharma Bokun Cheng Rauhin Sahu Xusheng Zhang Rana Mehdizadeh Divya Singh Dumitru Iacobas Praveen Ballabh Source Type: research