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Cancer: Liver Cancer
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Total 30263 results found since Jan 2013.
TMEM64 is highly expressed in hepatocellular carcinoma and promotes tumor cell proliferation and invasion
CONCLUSION: A high TMEM64 expression may serve as an independent risk factor for poor prognosis of HCC and promotes proliferation, migration, and invasion of HCC cells in vitro.PMID:37712271 | PMC:PMC10505578 | DOI:10.12122/j.issn.1673-4254.2023.08.11
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: D Cao J Cai Y Li R Dong Z Wang X Zuo Source Type: research
Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis
CONCLUSION: DRW inhibits the occurrence and progression of HCC, and this effect is mediated possibly by inducing cell cycle arrest and apoptosis.PMID:37712265 | PMC:PMC10505577 | DOI:10.12122/j.issn.1673-4254.2023.08.05
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Lan K Wang Z Lan H Zhou J Sun Source Type: research
TMEM64 is highly expressed in hepatocellular carcinoma and promotes tumor cell proliferation and invasion
CONCLUSION: A high TMEM64 expression may serve as an independent risk factor for poor prognosis of HCC and promotes proliferation, migration, and invasion of HCC cells in vitro.PMID:37712271 | PMC:PMC10505578 | DOI:10.12122/j.issn.1673-4254.2023.08.11
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: D Cao J Cai Y Li R Dong Z Wang X Zuo Source Type: research
Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis
CONCLUSION: DRW inhibits the occurrence and progression of HCC, and this effect is mediated possibly by inducing cell cycle arrest and apoptosis.PMID:37712265 | PMC:PMC10505577 | DOI:10.12122/j.issn.1673-4254.2023.08.05
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Lan K Wang Z Lan H Zhou J Sun Source Type: research
Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies
This article summarizes the pharmacological effects, pharmacokinetic characteristics, and toxicity of luteolin against liver diseases, and provides prospect. The results indicate that luteolin improves liver lesions through various mechanisms, including inhibiting inflammatory factors, reducing oxidative stress, regulating lipid balance, slowing down excessive aggregation of extracellular matrix, inducing apoptosis and autophagy of liver cancer cells. Pharmacokinetics research manifested that due to metabolic effects, the bioavailability of luteolin is relatively low. It is worth noting that appropriate modification, new d...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 15, 2023 Category: Drugs & Pharmacology Authors: Chenhao Yao Shu Dai Cheng Wang Ke Fu Rui Wu Xingtao Zhao Yuxin Yao Yunxia Li Source Type: research
Oncogenic pathways refine a new perspective on the classification of hepatocellular carcinoma
CONCLUSIONS: ADP provides a new perspective for identifying patients at high risk of recurrence and could optimize precision treatment to improve the clinical outcomes in HCC.PMID:37714446 | DOI:10.1016/j.cellsig.2023.110890
Source: Cellular Signalling - September 15, 2023 Category: Cytology Authors: Yuyuan Zhang Zaoqu Liu Jie Li Bailu Wu Xin Li Mengjie Duo Hui Xu Long Liu Xiaoxing Su Xuhua Duan Peng Luo Jian Zhang Zhen Li Source Type: research
TMEM64 is highly expressed in hepatocellular carcinoma and promotes tumor cell proliferation and invasion
CONCLUSION: A high TMEM64 expression may serve as an independent risk factor for poor prognosis of HCC and promotes proliferation, migration, and invasion of HCC cells in vitro.PMID:37712271 | PMC:PMC10505578 | DOI:10.12122/j.issn.1673-4254.2023.08.11
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: D Cao J Cai Y Li R Dong Z Wang X Zuo Source Type: research
Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis
CONCLUSION: DRW inhibits the occurrence and progression of HCC, and this effect is mediated possibly by inducing cell cycle arrest and apoptosis.PMID:37712265 | PMC:PMC10505577 | DOI:10.12122/j.issn.1673-4254.2023.08.05
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Lan K Wang Z Lan H Zhou J Sun Source Type: research
TMEM64 is highly expressed in hepatocellular carcinoma and promotes tumor cell proliferation and invasion
CONCLUSION: A high TMEM64 expression may serve as an independent risk factor for poor prognosis of HCC and promotes proliferation, migration, and invasion of HCC cells in vitro.PMID:37712271 | DOI:10.12122/j.issn.1673-4254.2023.08.11
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: D Cao J Cai Y Li R Dong Z Wang X Zuo Source Type: research
Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis
CONCLUSION: DRW inhibits the occurrence and progression of HCC, and this effect is mediated possibly by inducing cell cycle arrest and apoptosis.PMID:37712265 | DOI:10.12122/j.issn.1673-4254.2023.08.05
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Lan K Wang Z Lan H Zhou J Sun Source Type: research
Resveratrol Inhibits Hepatocellular Carcinoma Progression Through Regulating Exosome Secretion
CONCLUSION: Resveratrol inhibits hepatocellular carcinoma progression by regulating exosome secretion and contents.PMID:37711128 | DOI:10.2174/0929867331666230914090053
Source: Current Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Kun Tong Pingfeng Wang Ying Li Yaoyao Tong Xuejie Li Shirong Yan Pei Hu Source Type: research
Lung immune prognostic index ‑based nomogram for recurrence of hepatocellular carcinoma after postoperative adjuvant TACE
CONCLUSION: Preoperative LIPI might be a powerful predictor for RFS in HCC patients received PA-TACE. The LIPI-based nomogram could further effectively predict the risk of recurrence and help clinicians formulate personalized follow-up strategies and adjuvant therapy to improve patient outcomes.PMID:37707573 | DOI:10.1007/s00432-023-05413-7
Source: Clin Med Res - September 14, 2023 Category: Research Authors: Yuxin Liang Ruoyi Yang Jin Shang Deyuan Zhong Qinyan Yang Yuhao Su Ying Shi Xiaolun Huang Source Type: research
Synthesis and its characterisation of selenium/silver/chitosan and cellular toxicity against liver carcinoma cells studies
Nat Prod Res. 2023 Sep 14:1-9. doi: 10.1080/14786419.2023.2256023. Online ahead of print.ABSTRACTLiver cancer is one of the most common lethal malignancy in the world. To treat liver cancer, new cure options are crucial. The use of natural substances along nanosciences may provide healing with lower toxicity and a smaller amount of side properties. In this research, The three-component selenium-silver-chitosan nanocomposite (Se-Ag-CS NCs) were synthesised with the help of ultrasound in a stepwise manner. The as-synthesised Se-Ag-CS NCs were characterised accordingly by applying powder X-Ray diffraction (PXRD), Fourier tran...
Source: Natural Product Research - September 14, 2023 Category: Biochemistry Authors: Fateme Momen Eslamieh-Ei Negar Sharifimoghaddammood Samira Amin Poustchi Tousi Samira Basharkhah Javad Mottaghipisheh Ali Es-Haghi Mohammad Ehsan Taghavizadeh Yazdi Marcello Iriti Source Type: research
PYCR2 promotes growth and aerobic glycolysis in human liver cancer by regulating the AKT signaling pathway
Biochem Biophys Res Commun. 2023 Sep 9;680:15-24. doi: 10.1016/j.bbrc.2023.09.007. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) is the world's third most fatal cancer. Because metabolic rewiring is a hallmark of HCC, studies into the causes of aberrant glycolysis could provide insight into novel HCC therapeutic strategies. Pyrroline-5-carboxylate reductase 2 (PYCR2), a key enzyme of proline synthesis, has previously been found to play vital roles in various malignancies regarding amino acid metabolism and oxidative stress response. Our study investigated the mechanistic function of PYCR2 in HCC. We used Gen...
Source: Biochemical and Biophysical Research communications - September 14, 2023 Category: Biochemistry Authors: Shaoyan Wang Wenyan Yi Zhenyu Xu Minyu Shi Source Type: research
