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Comparison of Strain-Encoding and Feature-Tracking Derived Myocardial Deformation Assessment of Left Ventricular Function in a Pediatric and Adult Congenital Heart Disease Cohort
ConclusionThere was poor agreement between SENC and FT derived GLS and GCS in a cohort of pediatric and ACHD patients, suggesting that SENC and FT cannot be used interchangeably.
Source: Pediatric Cardiology - March 3, 2022 Category: Cardiology Source Type: research

The Concept of Early Osteoarthritis and Its Significance in Regenerative Medicine
AbstractOsteoarthritis (OA) has been investigated as one of important target diseases for regenerative medicine. The concept of early OA has recently emerged under the assumption that if OA is detected and intervened early, progression of OA might be arrested or delayed before irreversible destruction of the joint occurs. This concept also matters in regenerative medicine for OA because new regenerative technologies can work better when joint damage is minimal. Diagnostic criteria for early OA have been suggested in this background to find a group of patients who have a higher possibility of developing full-blown OA. Howev...
Source: Tissue Engineering and Regenerative Medicine - March 4, 2022 Category: Biotechnology Source Type: research

Comparison of midazolam and propofol for sedation in pediatric diagnostic imaging studies.
CONCLUSION: Propofol seems to be more effective, achieve the appropriate sedation level more quickly, and provide a faster onset of sedation than midazolam in pediatric procedural sedation and analgesia. Propofol is preferred for imaging studies (computed tomography and magnetic resonance imaging) to reduce the occurrence of undesired motion artefacts. Although both drugs are safe to use for sedation before pediatric imaging procedures, propofol is preferred with appropriate preparation. PMID: 24918806 [PubMed - indexed for MEDLINE]
Source: Postgraduate Medicine - November 28, 2014 Category: Internal Medicine Tags: Postgrad Med Source Type: research

A rare pediatric variant of organized hematoma in the maxillary sinus
We report the first case of organized hematoma in the pediatric maxillary sinus with its clinico-radio-pathologic characteristics. Preoperative imaging was essential for the accurate diagnosis of this disease, and sublabial approach combined with endonasal endoscopic confirmation can be also recommended in the pediatric patient.
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - December 18, 2014 Category: ENT & OMF Source Type: research

Ocular Ultrasound—Point of Care Imaging of the Eye
Point of care sonography is a useful tool in the evaluation of both medical and traumatic ocular conditions. Traditional ocular evaluation including fundoscopy, computed tomography and magnetic resonance imaging involves significant patient cooperation, radiation exposure, and/or transfer of sometimes critically ill patients. Sonography is safe, does not utilize radiation and is done at the patient's bedside. Imaging is done through the closed eyelids which permit sonographic ocular examination even with significant eyelid edema and limited patient cooperation.
Source: Clinical Pediatric Emergency Medicine - December 1, 2015 Category: Emergency Medicine Authors: Russ Horowitz, John Bailitz Source Type: research

Evaluation of diagnostic performance of whole-body simultaneous PET/MRI in pediatric lymphoma
Conclusion Simultaneous whole-body PET/MRI is clinically feasible in pediatric lymphoma. PET/MRI performance is comparable to PET/CT for lesion detection and SUV measurements. Replacement of PET/CT with PET/MRI can significantly decrease radiation dose from diagnostic imaging in children.
Source: Pediatric Radiology - March 21, 2016 Category: Radiology Source Type: research

Triage tools for detecting cervical spine injury in pediatric trauma patients.
CONCLUSIONS: There are currently few studies assessing the diagnostic test accuracy of the NEXUS criteria and CCR in children. At the moment, there is not enough evidence to determine the accuracy of the Canadian C-spine Rule to detect CSI in pediatric trauma patients following blunt trauma. The confidence interval of the sensitivity of the NEXUS criteria between the individual studies showed a wide range, with a lower limit varying from 0.18 to 0.91 with a total of four false negative test results, meaning that if physicians use the NEXUS criteria in children, there is a chance of missing CSI. Since missing CSI could have...
Source: Cochrane Database of Systematic Reviews - December 7, 2017 Category: General Medicine Authors: Slaar A, Fockens MM, Wang J, Maas M, Wilson DJ, Goslings JC, Schep NW, van Rijn RR Tags: Cochrane Database Syst Rev Source Type: research

Evaluation and Management of Acute-Onset Hemiparesis in an Adolescent With Leukemia
We present a case of a 15-year-old boy with pre-B acute lymphoblastic leukemia on chemotherapy, having recently received a high-dose methotrexate infusion in addition to intrathecal methotrexate therapy, who presented to our ED with acute right-sided hemiparesis. He was initially suspected as having a possible ischemic stroke. Magnetic resonance imaging (diffusion-weighted and fluid-attenuated inversion recovery sequence) demonstrated focal areas of diffusion restriction, an early sign of delayed-onset methotrexate neurotoxicity. Our patient received appropriate supportive care and leucovorin rescue with gradual clinical r...
Source: Pediatric Emergency Care - March 1, 2018 Category: Emergency Medicine Tags: Illustrative Cases Source Type: research

The application of x-ray, computed tomography, and magnetic resonance imaging on 22 pediatric Langerhans cell histiocytosis patients with long bone involvement: A retrospective analysis
The studies focusing on x-ray, computed tomography (CT), and magnetic resonance imaging (MRI) in pediatric Langerhans cell histiocytosis (LCH) patients were still rare. Therefore, we aimed to evaluate the application of x-ray, CT, and MRI in pediatric LCH patients with long bone involvement. Total 22 pediatric LCH patients were included in this study. The diagnosis of LCH was confirmed by pathological examination. All patients were followed up for 3 years. X-ray, CT, or MRI was performed and the results were recorded for further analyses. Among 22 pediatric patients, x-ray (n = 20), CT (n = 18), or MRI (n = 1...
Source: Medicine - April 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

A synopsis on current practice in the diagnosis and management of patients with Turner syndrome in Turkey: A survey of 18 pediatric endocrinology centers*
Conclusions: Although we found some conformity between the current consensus and practice of the participating centers in Turkey regarding TS, further improvements are mandatory in the multi-disciplinary approach to address co-morbidities, which if unrecognized, may be associated with reduced quality of life, and even mortality. PMID: 29699389 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2018 Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research

Catcher’s Knee: Posterior Femoral Condyle Juvenile Osteochondritis Dissecans in Children and Adolescents
Conclusions: Catchers developed OCD at a younger age and in a more posterior location on the medial and lateral femoral condyles than noncatchers. These results may represent the effects of repetitive and persistent loading of the knees in the hyperflexed position required of catchers. Increased awareness of this risk may lead to surveillance and prevention programs. Level of Evidence: Level III—case-control study.
Source: Journal of Pediatric Orthopaedics - August 9, 2018 Category: Orthopaedics Tags: Sports Medicine Source Type: research

Swoop Portable MRI Cleared in U.S. for Bedside Scans
Magnetic resonance imaging (MRI) has become an integral part of medical care throughout much of the world, but access to this technology remains limited. Conventional MRI scanners need dedicated rooms with entry protocols, quench venting, and safety ...
Source: Medgadget - August 17, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Critical Care Emergency Medicine Neurology Orthopedic Surgery Pediatrics Radiology Source Type: blogs

MRI of tibial stress fractures: relationship between Fredericson classification and time to recovery in pediatric athletes
ConclusionNo differences were noted between Fredericson stress fracture grades and different time periods to recovery or between differences in recovery time and the return to full participation in sports, regardless of the use of assistive devices.
Source: Pediatric Radiology - August 17, 2020 Category: Radiology Source Type: research

Pediatric Lateral Patellar Dislocation: Is There a Role for Plain Radiography in the Emergency Department?
Conclusion: Osteochondral fractures were detected by plain radiography in 10% of patients presenting with lateral patellar dislocation and did not alter ED management. Pediatric patients with lateral patellar dislocations may be candidates for discharge from the ED after reduction without plain radiography. The modality by which to best determine the presence of a complicating osteochondral fracture (i.e., plain radiography, computed tomography, magnetic resonance imaging, or arthroscopy) may be left to the discretion of the orthopedic surgeon accepting the child in follow-up. Further study is needed to determine if forgoi...
Source: The Journal of Emergency Medicine - January 28, 2013 Category: Emergency Medicine Authors: Ernest A. Krause, Chia-Wei Lin, Henry W. Ortega, Samuel R. Reid Tags: Selected Topics: Emergency Radiology Source Type: research

Occult Intra-articular Knee Injuries in Children With Hemarthrosis
Conclusion: Seventy percent of the patients aged 9 to 14 years with traumatic knee hemarthrosis had a serious intra-articular injury that needed specific medical attention. Fifty-six percent of these patients had no visible injury on plain radiographs. Physicians who treat this group of patients should consider MRI to establish the diagnosis when there is no or minimal radiographic findings. The most common serious knee injury was a lateral patellar dislocation. This should be taken into consideration to improve prevention strategies and treatment algorithms in pediatric knee injuries.
Source: The American Journal of Sports Medicine - June 30, 2014 Category: Sports Medicine Authors: Askenberger, M., Ekstrom, W., Finnbogason, T., Janarv, P.-M. Tags: Epidemiology, Knee, general, Pediatric sports medicine Source Type: research