Filtered By:
Vaccination: Cancer Vaccines

This page shows you your search results in order of relevance. This is page number 20.

Order by Relevance | Date

Total 7677 results found since Jan 2013.

Fight Aging! Newsletter, May 13th 2013
In this study we used the hMTH1-Tg mouse model to investigate how oxidative damage to nucleic acids affects aging. hMTH1-Tg mice express high levels of the hMTH1 hydrolase that degrades 8-oxodGTP and 8-oxoGTP and excludes 8-oxoguanine from both DNA and RNA. Compared to wild-type animals, hMTH1-overexpressing mice have significantly lower steady-state levels of 8-oxoguanine in both nuclear and mitochondrial DNA of several organs, including the brain. hMTH1 overexpression prevents the age-dependent accumulation of DNA 8-oxoguanine that occurs in wild-type mice. These lower levels of oxidized guanines are associated with in...
Source: Fight Aging! - May 12, 2013 Category: Health Medicine and Bioethics Commentators Authors: Reason Tags: Newsletters Source Type: blogs

Isolation and Identification of Renal Cell Carcinoma-derived Peptides Associated with GP96.
Abstract We determined the possible associated determinants and analyzed whether gp96-_associated antigenic peptides can be found in renal cell carcinoma (RCC). The gp96-peptide complexes were chromatographically purified from resected tumor tissue of RCC patients. SDS-PAGE and Western blot analysis confirmed gp96 using the gp96 monoclonal antibody, and its concentration was measured using BCA. Approximately 20 to 50 μg gp96-peptide complexes was obtained from 1 g RCC tissue. The mass spectrometry (MS) analysis of the eluted peptides included the initial profiling using matrix-assisted laser desorption/ioniza...
Source: Technology in Cancer Research and Treatment - February 22, 2013 Category: Cancer & Oncology Authors: Li HZ, Li CW, Li CY, Zhang BF, Li LT, Li JM, Zheng JN, Chang JW Tags: Technol Cancer Res Treat Source Type: research

What is BUKO Pharma-Kampagne?
http://www.en.bukopharma.de/BUKO Pharma-Kampagne was founded with the aim of examining the activities of the German pharmaceutical industry in Third World countries. We want to implement changes by taking  special actions and informing the public in detail. Pharma-Kampagne is a campaigning group of the Bundeskoordination Internationalismus(BUKO) (Federal Coordination of Internationalism) uniting 130 German action and solidarity groups working in favour of the Third World. More than 20 years ago, BUKO Pharma-Kampagne started to pay attention to the theme "Drugs and the Third World ". Today it is one of the fe...
Source: PharmaGossip - May 28, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs

Human papillomavirus (HPV) vaccine implementation in low and middle-income countries (LMICs): Health system experiences and prospects.
Abstract Prophylactic vaccines for human papillomavirus (HPV) are being introduced in many countries for the prevention of cervical cancer, the second most important cause of cancer-related death in women globally. This is likely to have a significant impact on the future burden of cervical cancer, particularly where screening is non-existent or limited in scale. Previous research on the challenges of vaccinating girls with the HPV vaccine has focused on evidence from developed countries. We conducted a systematic search of the literature in order to describe the barriers and challenges to implementation of HPV va...
Source: Vaccine - June 15, 2013 Category: Allergy & Immunology Authors: Wigle J, Coast E, Watson-Jones D Tags: Vaccine Source Type: research

Active immunotherapy in HER2 overexpressing breast cancer: current status and future perspectives
Conclusions Development of effective vaccines for BC remains a distinct challenge but is likely to become a substantial advance for patients with HER2-overexpressing BCs.
Source: Annals of Oncology - June 24, 2013 Category: Cancer & Oncology Authors: Milani, A., Sangiolo, D., Montemurro, F., Aglietta, M., Valabrega, G. Tags: reviews Source Type: research

Vaccines Can Cause Infertility
Conclusion What I have discovered, I am sure that many would agree, is absolutely horrific. It appears that many of the recommended vaccinations are known by the governments and pharmaceutical industries to cause infertility. Many of these vaccines are mandatory. We need to ask ourselves why our governments are deliberately force-vaccinating us with vaccines known to cause infertility. Another question we need to ask is why are so many studies being funded to study the subject area surrounding vaccines and infertility. Many leading professionals believe that these vaccines are being offered as part of a global depopulation...
Source: vactruth.com - July 20, 2013 Category: Health Medicine and Bioethics Commentators Authors: Christina England Tags: Christina England Top Stories infertility Premature Ovarian Failure Sterilization Tetanus Vaccines Vaccine Safety Source Type: blogs

Counseling about the HPV Vaccine: Desexualize, Educate, and Advocate
Abstract: Information is provided for clinicians who treat adolescents and adult women to use when counseling patients about human papillomavirus (HPV) vaccine. A literature search was done to determine: (1) reasons for refusal of the vaccine, including cost and concerns that immunization against HPV will lead to promiscuity; (2) potential for non-sexual transmission of HPV; (3) non-genital locations of HPV; (4) non-genital cancers associated with HPV.Vaccines for Children Program and the Affordable Care Act eliminate many costs. Neither biological nor behavioral evidence supports the idea that sexual behavior changes afte...
Source: Journal of Pediatric and Adolescent Gynecology - July 27, 2013 Category: OBGYN Authors: Richard M. Grimes, Laura J. Benjamins, Kendra L. Williams Tags: Tips for Clinicians Source Type: research

The burden of invasive pneumococcal disease in children with underlying risk factors in North America and Europe
ConclusionDespite the heterogeneity of the studies identified, the available data show a substantial incidence of IPD in at‐risk children, particularly those who are immunocompromised. Further research is needed to determine the true risk of IPD in at‐risk children, particularly in the post‐PCV period, and to understand the benefits of vaccination and optimal vaccination schedules.
Source: International Journal of Clinical Practice - July 19, 2013 Category: Internal Medicine Authors: M. A. Rose, D. Christopoulou, T. T. H. Myint, I. Schutter Tags: Systematic Review Source Type: research

Influenza vaccination in children being treated with chemotherapy for cancer.
CONCLUSIONS: Paediatric oncology patients receiving chemotherapy are able to generate an immune response to the influenza vaccine, but it remains unclear whether this immune response protects them from influenza infection or its complications. We are awaiting results from well-designed RCTs addressing the clinical benefit of influenza vaccination in these patients. PMID: 23904194 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - August 1, 2013 Category: Journals (General) Authors: Goossen GM, Kremer LC, van de Wetering MD Tags: Cochrane Database Syst Rev Source Type: research

Inequalities in the uptake of Human Papillomavirus Vaccination: a systematic review and meta-analysis
Conclusions We found strong evidence for differences in HPV vaccination initiation by ethnicity and healthcare coverage, but did not find a strong association with parental education or family income variables. The majority of studies originated from the USA. Population-based studies reporting both initiation and completion of the HPV vaccination programme are required to establish patterns of uptake in different healthcare contexts.
Source: International Journal of Epidemiology - August 2, 2013 Category: Epidemiology Authors: Fisher, H., Trotter, C. L., Audrey, S., MacDonald-Wallis, K., Hickman, M. Tags: Inequalities Source Type: research

Bicistronic DNA Vaccines Simultaneously Encoding HIV, HSV and HPV Antigens Promote CD8(+) T Cell Responses and Protective Immunity.
Abstract Millions of people worldwide are currently infected with human papillomavirus (HPV), herpes simplex virus (HSV) or human immunodeficiency virus (HIV). For this enormous contingent of people, the search for preventive and therapeutic immunological approaches represents a hope for the eradication of latent infection and/or virus-associated cancer. To date, attempts to develop vaccines against these viruses have been mainly based on a monovalent concept, in which one or more antigens of a virus are incorporated into a vaccine formulation. In the present report, we designed and tested an immunization strategy...
Source: Herpes - August 24, 2013 Category: Infectious Diseases Authors: Santana VC, Diniz MO, Cariri FA, Ventura AM, Cunha-Neto E, Almeida RR, Campos MA, Lima GK, Ferreira LC Tags: PLoS One Source Type: research

Modifiable influences on female HPV vaccine uptake at the clinic encounter level: A literature review
ConclusionsSix influences are modifiable and potentially amenable to being addressed at the clinic encounter level: (a) cost and insurance coverage, (b) provider recommendation, (c) vaccination opportunity, (d) HPV and HPV vaccine knowledge, (e) vaccine safety concerns, and (f) HPV risk. Implications for practiceNPs have an important role in improving HPV vaccine uptake and research suggests several areas they can address to increase vaccination during clinic visits.
Source: Journal of the American Academy of Nurse Practitioners - August 22, 2013 Category: Nursing Authors: Stephanie L. Small, Carolyn M. Sampselle, Kristy K. Martyn, Amanda F. Dempsey Tags: REVIEW Source Type: research

Active immunotherapy using dendritic cells in the treatment of glioblastoma multiforme
Conclusions: Active immunotherapy, specifically with autologous DCs loaded with autologous tumor cells, seems to have the potential of increasing median OS and prolonged tumor PFS with minimal complications. Larger clinical trials are needed to show the potential benefits of active immunotherapy.
Source: Cancer Treatment Reviews - June 24, 2013 Category: Cancer & Oncology Authors: Amade Bregy, Theresa M. Wong, Ashish H. Shah, John M. Goldberg, Ricardo J. Komotar Tags: Anti-Tumour Treatment Source Type: research

Glycodendrimers as new tools in the search for effective anti-HIV DC-based immunotherapies
Abstract: Dendritic cells (DC), which play a major role in development of cell-mediated immunity, represent opportunities to develop novel anti-HIV vaccines. Dendrimers have been proposed as new carriers to ameliorate DC antigen loading and in this way, we have determined the potential use of maltose decorated neutrally and positively charged G4 glycodendrimers. Thus, immunostimulatory properties of these glycodendrimers on human DC were evaluated in the context of HIV infection. We have demonstrated that DC treated with glycodendrimers were fully functional with respect to viability, maturation and HIV-derived antigens up...
Source: Nanomedicine : Nanotechnology, Biology, and Medicine - March 18, 2013 Category: Nanotechnology Authors: E. Vacas Córdoba, M. Pion, B. Rasines, D. Filippini, H. Komber, M. Ionov, M. Bryszewska, D. Appelhans, M.A. Muñoz-Fernández Tags: Immunology, Dendritic Cell Modulation, HIV, Maltose Functionalized Dendrimer Source Type: research