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Structure-function of DHEA binding proteins
Vitam Horm. 2023;123:587-617. doi: 10.1016/bs.vh.2022.12.002. Epub 2022 Dec 16.ABSTRACTDehydroepiandrosterone (3β-hydroxy-5-androsten-17-one, DHEA) and its sulfated metabolite DHEA-S are the most abundant circulating steroids and are precursors for active sex steroid hormones, estradiol and testosterone. DHEA has a broad range of reported effects in the central nervous system (CNS), cardiovascular system, adipose tissue, kidney, liver, and in the reproductive system. The mechanisms by which DHEA and DHEA-S initiate their biological effects are diverse. DHEA and DHEA-S may directly bind to plasma membrane (PM) receptors, i...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Barbara J Clark Carolyn M Klinge Source Type: research
A novel multifunctional chitosan-gelatin/carboxymethyl cellulose-alginate bilayer hydrogel containing human placenta extract for accelerating full-thickness wound healing
This study presents a multifunctional bi-layer hydrogel incorporating HPE for accelerating full-thickness wound healing through sustained HPE release, inhibition of bacteria invasion, and promotion of cell proliferation. The upper layer of the scaffold, known as the dressing layer, is composed of carboxymethyl cellulose and sodium alginate, serving as a supportive layer for cell proliferation. The under layer, referred to as the regenerative layer, is composed of chitosan and gelatin, providing an extracellular matrix-like, porous, moist, and antibacterial environment for cell growth. The scaffold was optimized to replicat...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Saeed Seifi Amir Shamloo Sayed Navid Tavoosi Aram Almasi-Jaf Hossein Shaygani Mohammad Reza Sayah Source Type: research
Preparation and characterization of polyvinyl alcohol/sodium lignosulfonate/black rice anthocyanin extract agricultural film for monitoring soil pH
This study focuses on the formulation of polyvinyl alcohol (PVA)-based films with pH-sensitive properties and ultraviolet (UV) resistance by incorporating sodium lignosulfonate (LS) and varying concentrations of black rice anthocyanin extract (BRE) into PVA matrix. The films were characterized through Fourier transform-infrared spectroscopy (FT-IR), X-ray diffraction (XRD), tensile test, water vapor permeability (WVP), and ultraviolet-visible (UV-vis) spectroscopy. The results indicated that BRE and LS effectively formed strong hydrogen bonds with PVA, leading to reduced film crystallinity, improved mechanical properties, ...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Lili Ren Siqi Yang Nan Wu Jian Xu Source Type: research
A novel multifunctional chitosan-gelatin/carboxymethyl cellulose-alginate bilayer hydrogel containing human placenta extract for accelerating full-thickness wound healing
This study presents a multifunctional bi-layer hydrogel incorporating HPE for accelerating full-thickness wound healing through sustained HPE release, inhibition of bacteria invasion, and promotion of cell proliferation. The upper layer of the scaffold, known as the dressing layer, is composed of carboxymethyl cellulose and sodium alginate, serving as a supportive layer for cell proliferation. The under layer, referred to as the regenerative layer, is composed of chitosan and gelatin, providing an extracellular matrix-like, porous, moist, and antibacterial environment for cell growth. The scaffold was optimized to replicat...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Saeed Seifi Amir Shamloo Sayed Navid Tavoosi Aram Almasi-Jaf Hossein Shaygani Mohammad Reza Sayah Source Type: research
Preparation and characterization of polyvinyl alcohol/sodium lignosulfonate/black rice anthocyanin extract agricultural film for monitoring soil pH
This study focuses on the formulation of polyvinyl alcohol (PVA)-based films with pH-sensitive properties and ultraviolet (UV) resistance by incorporating sodium lignosulfonate (LS) and varying concentrations of black rice anthocyanin extract (BRE) into PVA matrix. The films were characterized through Fourier transform-infrared spectroscopy (FT-IR), X-ray diffraction (XRD), tensile test, water vapor permeability (WVP), and ultraviolet-visible (UV-vis) spectroscopy. The results indicated that BRE and LS effectively formed strong hydrogen bonds with PVA, leading to reduced film crystallinity, improved mechanical properties, ...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Lili Ren Siqi Yang Nan Wu Jian Xu Source Type: research
Structure-function of DHEA binding proteins
Vitam Horm. 2023;123:587-617. doi: 10.1016/bs.vh.2022.12.002. Epub 2022 Dec 16.ABSTRACTDehydroepiandrosterone (3β-hydroxy-5-androsten-17-one, DHEA) and its sulfated metabolite DHEA-S are the most abundant circulating steroids and are precursors for active sex steroid hormones, estradiol and testosterone. DHEA has a broad range of reported effects in the central nervous system (CNS), cardiovascular system, adipose tissue, kidney, liver, and in the reproductive system. The mechanisms by which DHEA and DHEA-S initiate their biological effects are diverse. DHEA and DHEA-S may directly bind to plasma membrane (PM) receptors, i...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Barbara J Clark Carolyn M Klinge Source Type: research
Initial Evaluation of USP Apparatus 4 for Measuring Dissolution Profile of Man-Made Vitreous Fibers
We report the successful evaluation of a US Pharmacopeia Apparatus 4 (USP-4) system in measuring the dissolution profiles of man-made vitreous fibers (MMVF)i. Glass and stone wool fibers with different (high- and low-) solubility profiles were tested in closed-loop configuration using a sodium/potassium phosphate buffer solution or an acetate buffer, respectively. Results confirm a need to operate in diluted conditions to avoid silicon saturation in the simulant solution and suppression of fiber dissolution. A clear fiber-to-fiber differentiation with good cell-to-cell reproducibility was achieved. These findings support t...
Source: Toxicology Letters - September 16, 2023 Category: Toxicology Authors: J W Hoffman D V Okhrimenko E Chaudan Q Herault N Drnovsek E Pezennec A Aznar N Mascaraque S Haddouchi M Lecluse A A Badissi J de Cruz L Hi éronimus M Solvang Source Type: research
Effect of polysaccharides on conformational changes and functional properties of protein-polyphenol binary complexes: A comparative study
This study aimed to investigate the effect of different polysaccharides on the binding behavior and functional properties of soybean protein isolate (SPI)-quercetin (Que) complex. The binding behavior was assessed using multi-spectral technique with the Stern-Volmer equation, which confirmed the presence of static fluorescence quenching in Que and SPI. The addition of sodium alginate (SA) resulted in a reduction of the binding affinity between SPI and Que, while dextran (DX) exhibited some promoting effect. A slight blue shift was observed in amide I and amide II bands, indicating the presence of hydrophobic and electrosta...
Source: International Journal of Biological Macromolecules - September 16, 2023 Category: Biochemistry Authors: Zifan Zhang Taoran Li Yubo Zhang Juanjuan Shao Chengxiang Ye Hongwu Wang Beibei Zhu Yating Zhang Source Type: research
An experimental design study of photocatalytic activity of the Z-scheme silver iodide/tungstate binary nano photocatalyst
Environ Sci Pollut Res Int. 2023 Sep 16. doi: 10.1007/s11356-023-29730-z. Online ahead of print.ABSTRACTA binary AgI/ Ag2WO4 photocatalyst was fabricated and characterized by SEM, XRD, UV-Vis DRS, and FT-IR. It was then used to photodegrade sodium ceftriaxone (CTX) in an aqueous solution. The band gap energies of 2.95, 2.78, and 2.62 eV were obtained by the Kubelka-Munk model for Ag2WO4, AgI, and AgI/Ag2WO4 catalysts. The samples have pHPZC values of 6.9, 4.2, and 6.6, respectively. The synergistic photocatalytic activity of the coupled system depended on the AgI:Ag2WO4 mole ratio and grinding time (optimums:mole ratio of ...
Source: Environmental Science and Pollution Research International - September 16, 2023 Category: Environmental Health Authors: Sabereh Salesi Alireza Nezamzadeh-Ejhieh Source Type: research
Sports Nutrition Knowledge Questionnaires Developed for the Athletic Population: a Systematic Review
AbstractPurpose of ReviewSports nutrition (SN) is pivotal in aiding athletes to reach peak performance, minimize sport-related injuries, enhance career longevity, and improve general health. An accurate assessment of athletes ’ sports nutrition knowledge (SNK) is required to design targeted nutrition education programs aimed at enhancing both nutritional knowledge and dietary practices. This review systematically evaluates studies that use questionnaires to assess the SNK of athletes engaged in athletics.Recent FindingsThe literature search was conducted in PubMed®, Web of Science®, and Scopus®, and 375 potentially re...
Source: Current Nutrition Reports - September 16, 2023 Category: Nutrition Source Type: research
Preparation, thermal storage properties and application of sodium acetate trihydrate/expanded graphite composite phase change materials
Dalton Trans., 2023, Accepted Manuscript DOI: 10.1039/D3DT02785F, PaperKe-Wei Wang, Ting Yan, Liang-Chen Meng, Wei-Guo Pan The development of energy storage technology is beneficial to the efficient use of energy and sustainable development. As an effectual approach to store and transport thermal energy, latent heat storage... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - September 15, 2023 Category: Chemistry Authors: Ke-Wei Wang Source Type: research
Tailoring the growth route of lithium peroxide through the rational design of a sodium-doped nickel phosphate catalyst for lithium –oxygen batteries
Chem. Commun., 2023, Advance Article DOI: 10.1039/D3CC03323F, CommunicationSe-Si Li, Xing-He Zhao, Kai-Xue Wang, Jie-Sheng Chen Sodium-doped nickel phosphate nanorods with optimized electronic structure facilitate the uniform growth of sea cucumber-like Li2O2 with large reaction area. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - September 15, 2023 Category: Chemistry Authors: Se-Si Li Source Type: research
Sodium channel endocytosis drives axon initial segment plasticity
Sci Adv. 2023 Sep 15;9(37):eadf3885. doi: 10.1126/sciadv.adf3885. Epub 2023 Sep 15.ABSTRACTActivity-dependent plasticity of the axon initial segment (AIS) endows neurons with the ability to adapt action potential output to changes in network activity. Action potential initiation at the AIS highly depends on the clustering of voltage-gated sodium channels, but the molecular mechanisms regulating their plasticity remain largely unknown. Here, we developed genetic tools to label endogenous sodium channels and their scaffolding protein, to reveal their nanoscale organization and longitudinally image AIS plasticity in hippocamp...
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Am élie Fréal Nora Jamann Jolijn Ten Bos Jacqueline Jansen Naomi Petersen Thijmen Ligthart Casper C Hoogenraad Maarten H P Kole Source Type: research
Sivelestat sodium for treatment of patients with COVID-19-associated acute respiratory distress syndrome in intensive care unit: a single-center retrospective cohort study
CONCLUSION: Sivelestat sodium treatment is not correlated with the reduction of mortality or length of hospital stay, but is associated with reduced serum IL-6 level in patients with COVID-19-associated ARDS.PMID:37712261 | DOI:10.12122/j.issn.1673-4254.2023.08.01
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: M Luo H Hu Y Sun X Zhao Z Zeng Y Liu G Wu Source Type: research
