Filtered By:
Nutrition: Iron
This page shows you your search results in order of date. This is page number 17.
Order by Relevance | Date
Total 27491 results found since Jan 2013.
Accelerated Atherosclerosis in Beta Thalassemia
Am J Physiol Heart Circ Physiol. 2023 Sep 8. doi: 10.1152/ajpheart.00306.2023. Online ahead of print.ABSTRACTChildren with Beta Thalassemia (BT) present with an increase in carotid intima-medial thickness, an early sign suggestive of premature atherosclerosis. However, it is unknown if there is a direct relationship between BT and atherosclerotic disease. To evaluate this, WT (littermates) and BT (Hbbth3/+) mice, both male and female, were placed on a 3-month high fat diet with low-density lipoprotein receptor suppression via overexpression of proprotein convertase subtilisin/kexin type 9 (PCSK9) gain-of-function mutation ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 8, 2023 Category: Physiology Authors: Julian Hurtado Hassan Sellak Giji Joseph Caitlin V Lewis Crystal R Naudin Sergio Garcia James Robert Wodicka David R Archer W Robert Taylor Source Type: research
New iron export pathways acting via holo-ferritin secretion
Arch Biochem Biophys. 2023 Sep 6:109737. doi: 10.1016/j.abb.2023.109737. Online ahead of print.ABSTRACTFerritin is a spherical nanocage protein for iron storage, composed of 24 light- or heavy-polypeptide chain subunits. A single ferritin molecule can carry up to 4500 iron atoms in its core, which plays an important role in suppressing intracellular iron toxicity. Serum ferritin levels are used as a marker for the total amount of iron stored in the body. Most serum ferritin is iron-free (apo-ferritin) and it is unclear how ferritin is released from cells. Ferritin is secreted into serum via extracellular vesicles (EVs) or ...
Source: Archives of Biochemistry and Biophysics - September 8, 2023 Category: Biochemistry Authors: Izumi Yanatori Fumio Kishi Shinya Toyokuni Source Type: research
Accelerated Atherosclerosis in Beta Thalassemia
Am J Physiol Heart Circ Physiol. 2023 Sep 8. doi: 10.1152/ajpheart.00306.2023. Online ahead of print.ABSTRACTChildren with Beta Thalassemia (BT) present with an increase in carotid intima-medial thickness, an early sign suggestive of premature atherosclerosis. However, it is unknown if there is a direct relationship between BT and atherosclerotic disease. To evaluate this, WT (littermates) and BT (Hbbth3/+) mice, both male and female, were placed on a 3-month high fat diet with low-density lipoprotein receptor suppression via overexpression of proprotein convertase subtilisin/kexin type 9 (PCSK9) gain-of-function mutation ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 8, 2023 Category: Physiology Authors: Julian Hurtado Hassan Sellak Giji Joseph Caitlin V Lewis Crystal R Naudin Sergio Garcia James Robert Wodicka David R Archer W Robert Taylor Source Type: research
Arsenic fractionation and speciation in different textured soils supplied with farmyard manure and accumulation by sunflower under alkaline calcareous conditions
Environ Sci Pollut Res Int. 2023 Sep 8. doi: 10.1007/s11356-023-29659-3. Online ahead of print.ABSTRACTArsenic (As) is a naturally occurring element that is found in soil, water, and rocks. However, it can also be released into the environment through human activities. Arsenic is considered an environmental hazard because it is toxic to humans and animals and can cause serious health problems. Additionally, As-contaminated soil can limit plant growth and reduce crop yields, leading to economic losses for farmers. So, decreasing metal/metalloid solubility in soil by synthetic and organic amendments leads to better crop prod...
Source: Environmental Science and Pollution Research International - September 8, 2023 Category: Environmental Health Authors: Muhammad Awais Piracha Muhammad Ashraf Sher Muhammad Shahzad Sajid Masood Naeem Akhtar Rizwana Kausar Awais Shakoor Source Type: research
The bidirectional extracellular electron transfer process aids iron cycling by < em > Geoalkalibacter halelectricus < /em > in a highly saline-alkaline condition
This study advances the understanding of extremophilic microbial taxa capable of bidirectional EET and its role in barely investigated Fe cycling in highly saline-alkaline environments. It also offers research opportunities for understanding the membrane components involved in the bidirectional EET of G. halelectricus. The high rate of Fe3+ oxide reduction activity by G. halelectricus suggests its possible use as a biocatalyst in the anaerobic iron bioleaching process under neutral-alkaline pH conditions.PMID:37681980 | DOI:10.1128/aem.00609-23
Source: Applied and Environmental Microbiology - September 8, 2023 Category: Microbiology Authors: Sukrampal Yadav Chetan Sadhotra Sunil A Patil Source Type: research
Accelerated Atherosclerosis in Beta Thalassemia
Am J Physiol Heart Circ Physiol. 2023 Sep 8. doi: 10.1152/ajpheart.00306.2023. Online ahead of print.ABSTRACTChildren with Beta Thalassemia (BT) present with an increase in carotid intima-medial thickness, an early sign suggestive of premature atherosclerosis. However, it is unknown if there is a direct relationship between BT and atherosclerotic disease. To evaluate this, WT (littermates) and BT (Hbbth3/+) mice, both male and female, were placed on a 3-month high fat diet with low-density lipoprotein receptor suppression via overexpression of proprotein convertase subtilisin/kexin type 9 (PCSK9) gain-of-function mutation ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 8, 2023 Category: Physiology Authors: Julian Hurtado Hassan Sellak Giji Joseph Caitlin V Lewis Crystal R Naudin Sergio Garcia James Robert Wodicka David R Archer W Robert Taylor Source Type: research
The bidirectional extracellular electron transfer process aids iron cycling by < em > Geoalkalibacter halelectricus < /em > in a highly saline-alkaline condition
This study advances the understanding of extremophilic microbial taxa capable of bidirectional EET and its role in barely investigated Fe cycling in highly saline-alkaline environments. It also offers research opportunities for understanding the membrane components involved in the bidirectional EET of G. halelectricus. The high rate of Fe3+ oxide reduction activity by G. halelectricus suggests its possible use as a biocatalyst in the anaerobic iron bioleaching process under neutral-alkaline pH conditions.PMID:37681980 | DOI:10.1128/aem.00609-23
Source: Applied and Environmental Microbiology - September 8, 2023 Category: Microbiology Authors: Sukrampal Yadav Chetan Sadhotra Sunil A Patil Source Type: research
Accelerated Atherosclerosis in Beta Thalassemia
Am J Physiol Heart Circ Physiol. 2023 Sep 8. doi: 10.1152/ajpheart.00306.2023. Online ahead of print.ABSTRACTChildren with Beta Thalassemia (BT) present with an increase in carotid intima-medial thickness, an early sign suggestive of premature atherosclerosis. However, it is unknown if there is a direct relationship between BT and atherosclerotic disease. To evaluate this, WT (littermates) and BT (Hbbth3/+) mice, both male and female, were placed on a 3-month high fat diet with low-density lipoprotein receptor suppression via overexpression of proprotein convertase subtilisin/kexin type 9 (PCSK9) gain-of-function mutation ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 8, 2023 Category: Physiology Authors: Julian Hurtado Hassan Sellak Giji Joseph Caitlin V Lewis Crystal R Naudin Sergio Garcia James Robert Wodicka David R Archer W Robert Taylor Source Type: research
TFEB regulates cellular labile iron and prevents ferroptosis in a TfR1-dependent manner
In this study, TFEB overexpression promoted the clearance of misfolded α-synuclein and prevented ferroptosis and iron overload. TFEB overexpression up-regulated transferrin receptor 1 (TfR1) synthesis and increased the localization of TfR1 in the lysosome, facilitating lysosomal iron import and transient lysosomal iron storage. TFEB overexpression increased the levels of cellular iron-safe storage proteins (both ferritin light and heavy chains). These functions in iron metabolism maintain the cellular labile iron at a low level and electrical activity, even under iron overload conditions. Notably, lower levels of cellular...
Source: Free Radical Biology and Medicine - September 8, 2023 Category: Biology Authors: Leilei Chen Yue Ma Xizhen Ma Lin Liu Xianhui Jv Ang Li Qingqing Shen Wenting Jia Le Qu Limin Shi Junxia Xie Source Type: research
Correction: Iron-doped bimetallic boride Fe-Ni2B/NF-x nanoparticles toward efficient oxygen evolution reaction at a large current density
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Yajuan Zhang, Hui Xu, Xingwei Shi, Shengyue Ma To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - September 7, 2023 Category: Chemistry Authors: Yajuan Zhang Source Type: research
T-2 toxin induces cardiotoxicity by activating ferroptosis and inhibiting heme oxygenase-1
Chemosphere. 2023 Sep 5:140087. doi: 10.1016/j.chemosphere.2023.140087. Online ahead of print.ABSTRACTT-2 toxin, a natural secondary sesquiterpenoid metabolite produced by numerous strains of Fusarium fungi, is prevalent in both contaminated food and the environment. T-2 toxin is known to be highly toxic to the cardiovascular system, but the precise mechanisms that lead to T-2 toxin-induced cardiotoxicity are not yet fully comprehended. Recent findings indicate that ferroptosis is a pivotal factor in cardiovascular damage and exhibits a strong correlation with the detrimental impacts of T-2 toxin. The present study was des...
Source: Chemosphere - September 7, 2023 Category: Chemistry Authors: Chi Wang Jun He Hong Jin Haixin Xiao Shuangqing Peng Jianwei Xie Li Zhang Jiabin Guo Source Type: research
Rosiglitazone inhibits acyl-CoA synthetase long-chain family number 4 and improves secondary brain injury in a rat model of surgical brain injury
This study aimed to investigate the role of ACSL4 in SBI via the ferroptosis pathway. Ninety male Sprague-Dawley rats were examined using a model of SBI. Subsequently, the inhibitory effect of rosiglitazone on ACSL4 was assessed via western blot, real-time polymerase chain reaction (PCR), immunofluorescence, fluoro-jade C staining, Perl's staining, ROS assay, and neurological scoring. The results showed that compared with the Sham group, the protein levels of ACSL4 and transferrin were significantly increased after SBI. Administration of rosiglitazone significantly reduced neuronal necrosis, iron deposition, brain water co...
Source: Clinical and Experimental Pharmacology and Physiology - September 7, 2023 Category: Drugs & Pharmacology Authors: Jinchao Shen Min Qian Muyao Wu Jiafeng Tang Yating Gong Jie Li Jinfen Ji Baoqi Dang Source Type: research
Transcriptomic Profiling Identifies Ferroptosis-Related Gene Signatures in Ischemic Muscle Satellite Cells Affected by Peripheral Artery Disease
CONCLUSIONS: This is the first report documenting that genes known to be involved in ferroptosis are differentially expressed in human skeletal muscle affected by PAD. Targeting ferroptosis may be a novel therapeutic strategy to reduce PAD myopathy.PMID:37675635 | DOI:10.1161/ATVBAHA.123.319518
Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 7, 2023 Category: Cardiology Authors: Lillian Tran Bowen Xie Edwyn Assaf Ricardo Ferrari Iraklis I Pipinos George P Casale Roberto Ivan Mota Alvidrez Simon Watkins Ulka Sachdev Source Type: research
