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Nutrition: Carbohydrates
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Carbohydrate antigen 125 in atrial fibrillation
This article reviews the role of CA-125 in patients with atrial fibrillation.PMID:37683718 | DOI:10.1016/j.cca.2023.117550
Source: International Journal of Clinical Chemistry - September 8, 2023 Category: Chemistry Authors: Rangrang Zhang Weidong Jin Minglei Han Yonglan Hou Source Type: research
N-methyl-O-benzylhydroxylamine derivatives of sialylated oligosaccharides, their synthesis and separation with reversed-phase HPLC
Carbohydr Res. 2023 Sep 3;533:108939. doi: 10.1016/j.carres.2023.108939. Online ahead of print.ABSTRACTThe human milk trisaccharide 3'- sialyllactose was reacted with an excess of N-methyl-O-benzylhydroxylamine (MBHA) and the product 3'- sialyllactose-MBHA was isolated in high (91%) yield by solid-phase extraction. The isomeric trisaccharide 6'-sialyllactose-MBHA was also prepared, in this case by enzymatic sialylation of lactose-MBHA. A 50/50 mixture of the two sialyllactose-MBHA derivatives was easily separated by reversed-phase HPLC. The free oligosaccharides were recovered from their respective MBHA derivatives by acid...
Source: Carbohydrate Research - September 8, 2023 Category: Genetics & Stem Cells Authors: Thomas Norberg Elisabet Kallin Source Type: research
Linker length-dependent morphologies in self-assembled structures of anthracene glucosides
Carbohydr Res. 2023 Aug 31;533:108933. doi: 10.1016/j.carres.2023.108933. Online ahead of print.ABSTRACTAnthracenemethyl glucosides, that possess ethylene glycol linkers connecting the glucoside with anthracene moiety, are studied herein. Koenigs-Knorr glycosylation of ethylene glycol-tethered anthracene with acetobromo glucose, followed by removal of the protecting groups, lead to the facile formation of the target glucosides. Aq. solutions of these anthracene glucosides readily undergo self-assembly, with critical aggregation concentration varying between 0.4 and 1 mM, depending on the linker, being ethylene-, di- and te...
Source: Carbohydrate Research - September 8, 2023 Category: Genetics & Stem Cells Authors: Anne George Narayanaswamy Jayaraman Source Type: research
N-methyl-O-benzylhydroxylamine derivatives of sialylated oligosaccharides, their synthesis and separation with reversed-phase HPLC
Carbohydr Res. 2023 Sep 3;533:108939. doi: 10.1016/j.carres.2023.108939. Online ahead of print.ABSTRACTThe human milk trisaccharide 3'- sialyllactose was reacted with an excess of N-methyl-O-benzylhydroxylamine (MBHA) and the product 3'- sialyllactose-MBHA was isolated in high (91%) yield by solid-phase extraction. The isomeric trisaccharide 6'-sialyllactose-MBHA was also prepared, in this case by enzymatic sialylation of lactose-MBHA. A 50/50 mixture of the two sialyllactose-MBHA derivatives was easily separated by reversed-phase HPLC. The free oligosaccharides were recovered from their respective MBHA derivatives by acid...
Source: Carbohydrate Research - September 8, 2023 Category: Genetics & Stem Cells Authors: Thomas Norberg Elisabet Kallin Source Type: research
Linker length-dependent morphologies in self-assembled structures of anthracene glucosides
Carbohydr Res. 2023 Aug 31;533:108933. doi: 10.1016/j.carres.2023.108933. Online ahead of print.ABSTRACTAnthracenemethyl glucosides, that possess ethylene glycol linkers connecting the glucoside with anthracene moiety, are studied herein. Koenigs-Knorr glycosylation of ethylene glycol-tethered anthracene with acetobromo glucose, followed by removal of the protecting groups, lead to the facile formation of the target glucosides. Aq. solutions of these anthracene glucosides readily undergo self-assembly, with critical aggregation concentration varying between 0.4 and 1 mM, depending on the linker, being ethylene-, di- and te...
Source: Carbohydrate Research - September 8, 2023 Category: Genetics & Stem Cells Authors: Anne George Narayanaswamy Jayaraman Source Type: research
Antiglycation, antifibrillation and antioxidative effects of para coumaric acid and vitamin D; an in-vitro and in-silico comparative-cum-synergistic approach
Biochim Biophys Acta Gen Subj. 2023 Sep 5:130455. doi: 10.1016/j.bbagen.2023.130455. Online ahead of print.ABSTRACTDiabetes Mellitus is a metabolic disorder that results in impaired utilization of carbohydrates, lipids, and proteins. Severe hyperglycemia is its principal clinical symptom. Human serum albumin (HSA) is used as a model protein since it is viewed as a sign of glycaemic management because it is more likely to get glycated in diabetic people than other proteins. Para-coumaric acid (pCA), a phenolic acid, and Vitamin D (vit-D) are used as protective agents. In the present work, we deduce a synergistic-cum-compara...
Source: Biochimica et Biophysica Acta - September 7, 2023 Category: Biochemistry Authors: Rizwan Khan Imrana Naseem Source Type: research
Uterine fluid extracellular vesicles proteome is altered during the oestrous cycle
In this study, shotgun quantitative proteomics-based mass-spectrometry was employed to compare UF-EV proteomes at day 0, 7 and 16 of the oestrous cycle to understand the oestrous cycle dependant dynamics. Furthermore, different phase UF-EVs were supplemented in embryo cultures to evaluate their impact on embryo development. 159 UF-EV proteins were differentially enriched at different time points indicating the UF-EV proteome is cycle dependent. Overall, many identified pathways are important for normal uterine functions, early embryo development and its nutritional needs, such as antioxidant activity, cell morphology and c...
Source: Molecular and Cellular Proteomics : MCP - September 7, 2023 Category: Molecular Biology Authors: Johanna Piibor Andres Waldmann Keerthie Dissanayake Aneta Andronowska Marilin Ivask Madhusha Prasadani Ants Kavak Suranga Kodithuwakku Alireza Fazeli Source Type: research
Antiglycation, antifibrillation and antioxidative effects of para coumaric acid and vitamin D; an in-vitro and in-silico comparative-cum-synergistic approach
Biochim Biophys Acta Gen Subj. 2023 Sep 5:130455. doi: 10.1016/j.bbagen.2023.130455. Online ahead of print.ABSTRACTDiabetes Mellitus is a metabolic disorder that results in impaired utilization of carbohydrates, lipids, and proteins. Severe hyperglycemia is its principal clinical symptom. Human serum albumin (HSA) is used as a model protein since it is viewed as a sign of glycaemic management because it is more likely to get glycated in diabetic people than other proteins. Para-coumaric acid (pCA), a phenolic acid, and Vitamin D (vit-D) are used as protective agents. In the present work, we deduce a synergistic-cum-compara...
Source: Biochimica et Biophysica Acta - September 7, 2023 Category: Biochemistry Authors: Rizwan Khan Imrana Naseem Source Type: research
Uterine fluid extracellular vesicles proteome is altered during the oestrous cycle
In this study, shotgun quantitative proteomics-based mass-spectrometry was employed to compare UF-EV proteomes at day 0, 7 and 16 of the oestrous cycle to understand the oestrous cycle dependant dynamics. Furthermore, different phase UF-EVs were supplemented in embryo cultures to evaluate their impact on embryo development. 159 UF-EV proteins were differentially enriched at different time points indicating the UF-EV proteome is cycle dependent. Overall, many identified pathways are important for normal uterine functions, early embryo development and its nutritional needs, such as antioxidant activity, cell morphology and c...
Source: Molecular and Cellular Proteomics : MCP - September 7, 2023 Category: Molecular Biology Authors: Johanna Piibor Andres Waldmann Keerthie Dissanayake Aneta Andronowska Marilin Ivask Madhusha Prasadani Ants Kavak Suranga Kodithuwakku Alireza Fazeli Source Type: research
Multi-level assessment of the origin, feeding area and organohalogen contamination on salmon from the Baltic Sea
Ecotoxicol Environ Saf. 2023 Sep 4;264:115424. doi: 10.1016/j.ecoenv.2023.115424. Online ahead of print.ABSTRACTThe Atlantic salmon (Salmo salar) population in the Baltic Sea consists of wild and hatchery-reared fish that have been released into the sea to support salmon stocks. During feeding migration, salmon migrate to different parts of the Baltic Sea and are exposed to various biotic and abiotic stressors, such as organohalogen compounds (OHCs). The effects of salmon origin (wild or hatchery-reared), feeding area (Baltic Main Basin, Bothnian Sea, and Gulf of Finland), and OHC concentration on the differences in hepati...
Source: Ecotoxicology and Environmental Safety - September 6, 2023 Category: Environmental Health Authors: Mirella Kanerva Nguyen Minh Tue Tatsuya Kunisue Kristiina Am Vuori Hisato Iwata Source Type: research
Gut microbiota profile and the influence of nutritional status on bacterial distribution in diabetic and healthy Tunisian subjects
Biosci Rep. 2023 Sep 5:BSR20220803. doi: 10.1042/BSR20220803. Online ahead of print.ABSTRACTGut microbiota plays a key role in the regulation of metabolism and immunity. We investigated the profile of gut microbiota and the impact of dietary intake on gut bacterial distribution in diabetic and healthy Tunisian subjects, aiming to identify a dysbiotic condition, hence opening the way to restore eubiosis and facilitate return to health. In the present research, we enrolled 10 type 1 diabetic (T1D), 10 type 2 diabetic (T2D) patients and 13 healthy (H) subjects. Illumina Miseq technology was used to sequence V3-V4 hypervariabl...
Source: Bioscience Reports - September 5, 2023 Category: Biomedical Science Authors: Meriem Fassatoui Azadeh Saffarian C éline Mulet Henda Jamoussi Amel Gamoudi Yossra Ben Halima Meriem Hechmi Sonia Abdelhak Abdelmajid Abid Philippe J Sansonetti Thierry Pedron Rym Kefi Source Type: research
Insight into biomolecular interaction-based non-classical crystallization of bacterial biocement
Appl Microbiol Biotechnol. 2023 Sep 5. doi: 10.1007/s00253-023-12736-5. Online ahead of print.ABSTRACTIn an attempt to draw a correlation between calcium carbonate (CaCO3) precipitation and biomacromolecules such as extracellular polymeric substances and enzyme activity in biomineralizing microbe, this report aims to elucidate the ureolytic and ammonification route in Paenibacillus alkaliterrae to explore the possible role of organic biomolecule(s) present on cell surface in mediating nucleation and crystallization of biogenic CaCO3. After 168 h of biomineralization in ureolysis and ammonification, 2.2 g/l and 0.87 g/l of ...
Source: Applied Microbiology and Biotechnology - September 5, 2023 Category: Microbiology Authors: Ankita Debnath Chinmay Hazra Ramkrishna Sen Source Type: research
Carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 in gastric cancer and their relationship with clinical prognosis
CONCLUSION: The expression levels of serum tumor markers CEA, CA199 and CA724 in patients with GC are high and rise with the increase of TNM stage. The levels of CEA, CA199 and CA724 are related to age, TNM stage, lymph node metastasis and tumor diameter. The combined detection of CEA, CA199 and CA724 is helpful to improve the diagnostic accuracy of GC with high clinical guidance value.PMID:37663935 | PMC:PMC10473936 | DOI:10.4251/wjgo.v15.i8.1475
Source: Cancer Control - September 4, 2023 Category: Cancer & Oncology Authors: Ran Wang Chun-Lei Zuo Rui Zhang Li-Mei Zhu Source Type: research
Improving prognosis and assessing adjuvant chemotherapy benefit in locally advanced rectal cancer with deep learning for MRI: a retrospective, multi-cohort study
CONCLUSION: The MuST model accurately and non-invasively predicted OS, DM, and LR. A specific and direct tool linking chemotherapy decisions and benefit quantification has also been provided.PMID:37660753 | DOI:10.1016/j.radonc.2023.109899
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 3, 2023 Category: Radiology Authors: Song Zhang Guoxiang Cai Peiyi Xie Caixia Sun Bao Li Weixing Dai Xiangyu Liu Qi Qiu Yang Du Zhenhui Li Zhenyu Liu Jie Tian Source Type: research
