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Early identification and treatment for peripheral arterial disease in patients with ischemic cerebrovascular disease
AbstractIschemic cerebrovascular disease (ICVD) is a major cause of mortality and disability worldwide and is often caused by atherosclerosis. As a systemic disease, atherosclerosis usually affects multiple vascular beds, mainly including cerebral, coronary, and peripheral arteries. Therefore, ICVD is easily complicated by lower-extremity peripheral arterial disease (PAD). ICVD patients  with PAD have more serious symptoms and a worse prognosis, however, neurologists might neglect the evaluation and management of the coexistent PAD, and there is still a lack of consensuses about the diagnosis and treatment for such patie...
Source: European Journal of Medical Research - February 23, 2023 Category: Research Source Type: research

A Cohort Study on the Safety and Efficacy of Warfarin and Rivaroxaban in Anticoagulant Therapy in Patients with Atrial Fibrillation Study
CONCLUSION: Compared with warfarin, rivaroxaban anticoagulant therapy has the same advantage in tolerance and prevention of thromboembolism in patients with AF, but rivaroxaban can effectively reduce the risk of bleeding in patients with AF.PMID:35845939 | PMC:PMC9283039 | DOI:10.1155/2022/4611383
Source: Biomed Res - July 18, 2022 Category: Research Authors: Li Wang Wentao Yao Source Type: research

Tamperless Tensor Elastography Imaging
Measuring and mapping nervous tissue microstructure noninvasively is a long sought-after goal in neuroscience. Several neuropathologies – such as cancer and stroke – are associated with changes in tissue microstructure. Changes in material properties, such as stiffness, represent a sensitive measure of underlying changes in tissue architecture, organization, and microstructure. Elastography techniques used to map material stiffness typically involves measuring displacement resulting from shear waves of known frequency imposed on the material by an external actuator or tamper. Material stiffness is estimated from measu...
Source: NIH OTT Licensing Opportunities - May 10, 2022 Category: Research Authors: ott8admin Source Type: research

Rationale and design of the Brazilian Diabetes Study: a prospective cohort of type 2 diabetes
CONCLUSION: The BDS will be the first large population-based cohort dedicated to the identification of clinical phenotypes of T2D at higher risk of cardiovascular events. Data derived from this study will provide valuable information on risk estimation and prevention of cardiovascular and other diabetes-related events.PMID:35174749 | DOI:10.1080/03007995.2022.2043658
Source: Current Medical Research and Opinion - February 17, 2022 Category: Research Authors: Joaquim Barreto Vaneza Wolf Isabella Bonilha Beatriz Luchiari Marcus Lima Alessandra Oliveira Sofia Vitte Gabriela Machado Jessica Cunha Cynthia Borges Daniel Munhoz Vicente Fernandes Sheila Tatsumi Kimura-Medorima Ikaro Breder Marta Duran Fernandez Thiag Source Type: research

The cerebral microvasculature: Basic and clinical perspectives on stroke and glioma
AbstractMicrovascular networks are vital components of the cardiovascular system, performing many key roles in maintaining the health and homeostasis of the tissues and organs in which they develop. As discussed in this review, the molecular and cellular components within the microcirculation orchestrate critical processes to establish functional capillary beds, including organization of endothelial cell (EC) polarity, guiding investment of vascular pericytes (PCs), and building the specialized extracellular matrix (ECM) that comprises the vascular basement membrane (vBM). Herein, we further discuss the unique features of ...
Source: Microcirculation - November 23, 2020 Category: Research Authors: Maruf M. Hoque, Hanaa Abdelazim, Clifton Jenkins ‐Houk, Dawn Wright, Biraj M. Patel, John C. Chappell Tags: INVITED REVIEWS Source Type: research

The Cerebral Microvasculature: Basic and Clinical Perspectives on Stroke and Glioma
AbstractMicrovascular networks are vital components of the cardiovascular system, performing many key roles in maintaining the health and homeostasis of the tissues and organs in which they develop. As discussed in this review, the molecular and cellular components within the microcirculation orchestrate critical processes to establish functional capillary beds, including organization of endothelial cell (EC) polarity, guiding investment of vascular pericytes (PCs), and building the specialized extracellular matrix (ECM) that comprises the vascular basement membrane (vBM). Herein, we further discuss the unique features of ...
Source: Microcirculation - November 10, 2020 Category: Research Authors: Maruf M. Hoque, Hanaa Abdelazim, Clifton Jenkins ‐Houk, Dawn Wright, Biraj M. Patel, John C. Chappell Tags: INVITED REVIEW Source Type: research

Ultrasonography for Detecting Adhesions: Aspirin Continuation for Lung Resection Patients
Conclusion: Preoperative detection of pleural adhesions using ultrasonography was useful in selecting pulmonary resection patients who continued aspirin perioperatively.
Source: In Vivo - April 25, 2019 Category: Research Authors: YASUKAWA, M., TAIJI, R., MARUGAMI, N., KAWAGUCHI, T., KAWAI, N., SAWABATA, N., TOJO, T., TAKAHAMA, J., HAMAZAKI, N., HIRAI, T., TANIGUCHI, S. Tags: Clinical Studies Source Type: research

Risk Factors for Recurrent Carotid-Artery Stenosis Following Stenting Treatment.
CONCLUSIONS In this study, we identified that CAS was a reliable approach for carotid artery stenosis. Male sex, smoking, and hyperlipidemia were independent risk factors associated with restenosis. Thus, hyperlipidemia should be monitored and routine follow-up with ultrasonography are recommended especially for male patients with current or history of smoking. PMID: 30942198 [PubMed - in process]
Source: Medical Science Monitor - April 5, 2019 Category: Research Tags: Med Sci Monit Source Type: research

Role of Extracranial Carotid Duplex and Computed Tomography Perfusion Scanning in Evaluating Perfusion Status of Pericarotid Stenting.
In this study we found that "resistance index" of the carotid ultrasound could detect flow changes before and after the stenting procedure, thus having great capacity to replace the role of computed tomography perfusion exam. PMID: 27051669 [PubMed - in process]
Source: Biomed Res - April 8, 2016 Category: Research Authors: Lin CM, Chang YJ, Liu CK, Yu CS, Lu HH Tags: Biomed Res Int Source Type: research

High red blood cell distribution width and preclinical carotid atherosclerosis.
CONCLUSIONS: High RDW correlates with increased risk for preclinical and clinical carotid atherosclerosis. PMID: 26474348 [PubMed - in process]
Source: Biomarkers - February 18, 2016 Category: Research Tags: Biomarkers Source Type: research

Risk Factors for Silent Lacunar Infarction in Patients with Transient Ischemic Attack.
CONCLUSIONS Age, hypertension, hyperlipidemia, and carotid stenosis were independently associated with silent lacunar infarction in patients with TIA. PMID: 26864634 [PubMed - in process]
Source: Medical Science Monitor - February 14, 2016 Category: Research Tags: Med Sci Monit Source Type: research

Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging
; Mickael Tanter Non-invasive imaging deep into organs at microscopic scales remains an open quest in biomedical imaging. Although optical microscopy is still limited to surface imaging owing to optical wave diffusion and fast decorrelation in tissue, revolutionary approaches such as fluorescence photo-activated localization microscopy led to a striking increase in resolution by more than an order of magnitude in the last decade. In contrast with optics, ultrasonic waves propagate deep into organs without losing their coherence and are much less affected by in vivo decorrelation processes. However, their resolution is...
Source: Nature - November 25, 2015 Category: Research Authors: Claudia ErricoJuliette PierreSophie PezetYann DesaillyZsolt LenkeiOlivier CoutureMickael Tanter Tags: Letter Source Type: research

Association of Serum Chemerin Levels with Acute Ischemic Stroke and Carotid Artery Atherosclerosis in a Chinese Population.
CONCLUSIONS The results of this study suggest that the serum chemerin level may be an independent risk factor for AIS and carotid artery plaque instability in Chinese populations. PMID: 26471865 [PubMed - in process]
Source: Medical Science Monitor - October 19, 2015 Category: Research Tags: Med Sci Monit Source Type: research