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Total 19 results found since Jan 2013.

What Are the Classifications of Perinatal Stroke?
Discussion Perinatal stroke occurs in about 1:1000 live births and is a “focal vascular injury from the fetal period to 28 days postnatal age.” Perinatal stroke is the most common cause of hemiparetic cerebral palsy and causes other significant morbidity including cognitive deficits, learning disabilities, motor problems, sensory problems including visual and hearing disorders, epilepsy, and behavioral and psychological problems. Family members are also affected because of the potential anxiety and guilt feelings that having a child with a stroke presents, along with the care that may be needed over the child&#...
Source: PediatricEducation.org - May 1, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

What Are Some Risk Factors for Cerebral Palsy?
Discussion The term, cerebral palsy, or CP has gone through many iterations with the first description in 1861 by W.J. Little who described it as “The condition of spastic rigidity of the limbs of newborn children.” The most recent definition is from Rosenbaun et al. in 2007 which states it is “a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cog...
Source: PediatricEducation.org - March 9, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Transcranial Doppler Ultrasound During Critical Illness in Children: Survey of Practices in Pediatric Neurocritical Care Centers*
Conclusions: At least 27 pediatric neurocritical care centers use transcranial Doppler during clinical care. In the majority of centers, studies are performed and interpreted by credentialed personnel, and findings are used to guide clinical management. Further studies are needed to standardize these practices.
Source: Pediatric Critical Care Medicine - January 1, 2020 Category: Pediatrics Tags: Neurocritical Care Source Type: research

Transcranial Doppler Screening Adherence among Children with Sickle Cell Anemia Seen in the Emergency Department
To evaluate adherence to annual transcranial Doppler ultrasound (TCD) screening to prevent stroke among patients with sickle cell anemia (SCA) seen in the emergency department (ED).
Source: The Journal of Pediatrics - November 20, 2019 Category: Pediatrics Authors: Julie K. Weisman, Carrie E. Diamond, Sarah Kappa, Robert Sheppard Nickel Tags: Original Articles Source Type: research

Basic Hemodynamic Monitoring Using Ultrasound or Electrical Cardiometry During Transportation of Neonates and Infants*
Objectives: Electrical cardiometry and heart ultrasound might allow hemodynamic evaluation during transportation of critically ill patients. Our aims were 1) to test feasibility of stroke volume monitoring using electrical cardiometry or ultrasound during transportation and 2) to investigate if transportation impacts on electrical cardiometry and ultrasound reliability. Design: Prospective, pragmatic, feasibility cohort study. Setting: Mobile ICUs specialized for neonatal and pediatric transportation. Patients: Thirty hemodynamically stable neonates and infants. Interventions: Patients enrolled underwent pair...
Source: Pediatric Critical Care Medicine - November 1, 2017 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Neonatal Arterial Ischemic Stroke – A Hospital Based Active Surveillance Study in Germany
Conclusions NAIS is a rare but not negligible morbidity in newborns. Asymptomatic children account for 56% of NAIS in all neonates. In these, not only seizures but also other unexplained symptoms should trigger diagnostic work-up with cUS and cMRI. Negative initial ultrasound results do not exclude NAIS. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Klinische Padiatrie - May 30, 2017 Category: Pediatrics Authors: Klemme, Mathias Gerstl, Lucia Weinberger, Raphael Olivieri, Martin Flemmer, Andreas von Kries, R üdiger Felderhoff-M üser, Ursula Dzietko, Mark Tags: Original Article Source Type: research

Haemoglobin oxygen saturation, leucocyte count and lactate dehydrogenase are predictors of elevated cerebral blood flow velocity in Nigerian children with sickle cell anaemia.
CONCLUSIONS: These clinical and laboratory indices are characteristic of chronic hypoxia and severe anaemia and are predictors of abnormal cerebral blood flow velocity. They can be used to predict stroke risk in children with SCA when access to TCD screening is limited. PMID: 28388354 [PubMed - as supplied by publisher]
Source: Paediatrics and international child health - April 9, 2017 Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research

Fifty years of brain imaging in neonatal encephalopathy following perinatal asphyxia.
Abstract In the past brain imaging of term infants with hypoxic-ischemic encephalopathy (HIE) was performed with cranial ultrasound (cUS) and computed tomography (CT). Both techniques have several disadvantages sensitivity and specificity is limited compared with magnetic resonance imaging (MRI) and CT makes use of radiation. At present MRI including diffusion weighted MRI during the first week of life, has become the method of choice for imaging infants with HIE. In addition to imaging, blood vessels and blood flow can be visualized using MR angiography, MR venography, and arterial spin labeling. Since the use of...
Source: Pediatric Research - November 1, 2016 Category: Pediatrics Authors: Groenendaal F, de Vries LS Tags: Pediatr Res Source Type: research

Annelizabeth ’s story: Care that feels like home, close to home
When you’re 5, it’s nice to have a place that feels like a second home. Where there are lots of hugs. And songs. And games. And you can curl up and watch “Frozen,” your favorite movie. For Annelizabeth Jean-Baptiste, a spunky Waltham kindergartener, that place is Boston Children’s Hospital at Waltham. Annelizabeth, or Annie (but never Anna, she says), first came to Boston Children’s at Waltham two weeks after she was born. Her mother Elcie wasn’t expecting that her fourth child would need special care. “It was a difficult pregnancy. I was very excited and relieved when she was born.” But that sense of rel...
Source: Thrive, Children's Hospital Boston - August 29, 2016 Category: Pediatrics Authors: Lisa Fratt Tags: Our Patients’ Stories Boston Children's at Waltham Dr. Rachael Grace sickle cell disease Source Type: news

Monitoring of newborns at high risk for brain injury
Abstract Due to the increasing number of surviving preterm newborns and to the recognition of therapeutic hypothermia as the current gold standard in newborns with hypoxic-ischaemic encephalopathy, there has been a growing interest in the implementation of brain monitoring tools in newborns at high risk for neurological disorders. Among the most frequent neurological conditions and presentations in the neonatal period, neonatal seizures and neonatal status epilepticus, paroxysmal non-epileptic motor phenomena, hypoxic-ischaemic encephalopathy, white matter injury of prematurity and stroke require specif...
Source: Italian Journal of Pediatrics - May 13, 2016 Category: Pediatrics Source Type: research

The effects of malnutrition on cardiac function in African children
Conclusions In this largest study to date, we found no significant difference in cardiac function between hospitalised children with and without severe acute malnutrition. Further study is needed to determine if cardiac function is diminished in unstable malnourished children.
Source: Archives of Disease in Childhood - January 20, 2016 Category: Pediatrics Authors: Silverman, J. A., Chimalizeni, Y., Hawes, S. E., Wolf, E. R., Batra, M., Khofi, H., Molyneux, E. M. Tags: Epidemiologic studies, Stroke, Hypertension, Radiology, Clinical diagnostic tests, Radiology (diagnostics) Original article Source Type: research

Transcranial Doppler ultrasound in children with stroke and cerebrovascular disorders
This article summarizes the basic physics and variables used during TCD, recent pediatric data published on the use of TCD in stroke and cerebrovascular disorders and how it may impact diagnosis and management, and some issues to be resolved so that TCD can be put into clinical practice. Recent findings: In sickle cell disease in children, TCD is the gold standard stroke prediction tool. Recent data suggest that TCD may provide important information in ischemic stroke because of other childhood arteriopathies such as moyamoya syndrome, transient or focal cerebral arteriopathy, and genetic/syndromic causes. TCD may also det...
Source: Current Opinion in Pediatrics - November 10, 2015 Category: Pediatrics Tags: NEUROLOGY: Edited by Robert C. Tasker Source Type: research

Use of Oxygen Pulse in Predicting Doppler-Derived Maximal Stroke Volume in Adolescents.
This study examined both of these issues in a cohort of 44 healthy adolescent males and females (ages 14-16 years) who performed routine progressive cycle exercise to exhaustion. Gas exchange variables were measured by standard open circuit techniques. Stroke volume at rest and during exercise was assessed by the Doppler ultrasound method. At peak exercise O2 pulse correlated closely with stroke volume (r=0.73) with a SEE of 12.6 mL·beat-1. Values of maximal O2 pulse in non-athletic boys and girls were 13.3 ± 2.5 and 11.0 ± 1.7 mL·beat-1, respectively. After the initial workload, a steady rise was observed in O2 pulse,...
Source: Pediatric Exercise Science - July 17, 2015 Category: Pediatrics Authors: Unnithan V, Rowland TW Tags: Pediatr Exerc Sci Source Type: research

Ella’s story: Two rare diseases and the NICU roller coaster ride
“Everyone tells you that the NICU is a roller coaster ride. What they don’t tell you is that it’s a customized roller coaster ride just for you. You never know what’s coming at you next,” says Carrie Shea, whose daughter Ella spent her first three months of life in Boston Children’s Hospital NICU. Today, Ella is a “remarkably normal little girl,” says Carrie. It’s quite a feat for the three-year-old who was born with GACI (generalized arterial calcification of infancy), an extremely rare condition with an 85 percent mortality rate, and diagnosed with PKU (phenylketonuria), a second rare genetic disorder, ...
Source: Thrive, Children's Hospital Boston - March 5, 2015 Category: Pediatrics Authors: Lisa Fratt Tags: Our patients’ stories Source Type: news

What is the Remission Rate for Antithyroid Drug Treatment for Hyperthyroidism in Children?
Discussion The thyroid gland secrets two hormones – T4 which is a prohormone and T3 which is the biologically active hormone. Receptors for T3 are found in nearly all body tissues. T3 regulates metabolism and energy production. Organs most affected are the heart, liver and central nervous system as well as growth of the fetus and child. Hyperthyroidism is common with a prevalence rate of about 1-2% for women and 0.2% for men. The most common cause of thyrotoxicosis is Grave’s disease where autoantibodies to thyroid stimulating hormone (TSH) exist. These autoantibodies attach to thyroid tissue TSH receptors and...
Source: PediatricEducation.org - January 26, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news